PrepTutorEJDIC
- =longways
English Journal
- [The pericytes, endothelium monolayer, collagen and elastin chains as the elements of areolar tissue and the substrates of chemical reaction of glyserization].
- Titov VN, Shiriaeva IuK.AbstractThe microangiopathy under hyperglycemia and diabetes develops only in the microcirculation component of circulatory system. In this area considerable amount of pericytes is concentrated. These cells contain myofibrils and in circulatory mode envelop capillaries being situated on the outside of basilemma. It is possible that in a phylogenetic sense this is the earliest functional unity of endothelium monolayer as a pacemaker and pericytes as contractile elements which are the earliest "propeller" because of implementing the function of advancement of lymph, hemolymph and blood in capillaries. Probably, endothelium and pericytes formed the first variation of peristaltic "pump" for the purpose of blood advancement longwise of capillaries. Most probably, the state of distal part of arterial race (muscular type arterioles) impact the parameters of proximal part of arterial race (elastic type arterioles) and myocardium itself in the same extent as the state of "pump" in capillaries, endothelium and pericytes function impact the function of local peristaltic pumps (muscular type arterioles) in paracrine cenosis. It is supposed that the pericytes are the regulators of physical, hydraulic factor of activation of biologic reaction of transcitosis--excretion of nutrients and humoral mediators from capillaries to the pool of intercellular medium to perform the biologic function of homeostasis. Hyperglycemia, glycotoxins formation, bivalent substances (glyoxal, methilglyoxal, malonic dialdehyde) reacting simultaneously by both ends of molecule result in formation within collagen of areolar tissue of short transversal cross-links (glycosylation end product) which significantly increase rigidity (hardness) of capillary wall. In these conditions, myofibrils of pericytes no longer form directed deformation of capillary wall to effect peristalsis and advancement of hemolymph (blood later on) along capillaries according the synthesis of monolayer endothelium NO as a dilatation factor. This is the cause of blood circulation disturbance on the level of exchange capillaries and formation of chronic hypoxemia resulting in the only increase of rate of glycosylation chemical reaction. The microangiopathy is formed in the cells and tissues in an integrated pool of intercellular medium and never occurs in the cerebrospinal fluid pool where no hyperglycemia develops.
- Klinicheskaia laboratornaia diagnostika.Klin Lab Diagn.2011 Jul;(7):3-14.
- The microangiopathy under hyperglycemia and diabetes develops only in the microcirculation component of circulatory system. In this area considerable amount of pericytes is concentrated. These cells contain myofibrils and in circulatory mode envelop capillaries being situated on the outside of basil
- PMID 21901889
- [The dual role of OCT4].
- Stefanovic S, Pucéat M.SourceInserm UMR 633, Université Paris Descartes, programme Avenir, Equipe Cellules souches et cardogenése, Evry, France. sonia.stefanovic@inserm.fr
- Médecine sciences : M/S.Med Sci (Paris).2010 Apr;26(4):411-6. doi: 10.1051/medsci/2010264411.
- OCT4 encoded by pou5f1 is one of the most ancient and early transcription factors identified in the embryo. It has been longwise recognized as a gatekeeper for pluripotency of embryonic stem (ES) cell. Uncovered twenty years ago, its fame was built up from its key role in maintaining embryonic stem
- PMID 20412747
- Oct-3/4: not just a gatekeeper of pluripotency for embryonic stem cell, a cell fate instructor through a gene dosage effect.
- Stefanovic S, Pucéat M.SourceINSERM U421/I-Stem, Evry, France.
- Cell cycle (Georgetown, Tex.).Cell Cycle.2007 Jan 1;6(1):8-10. Epub 2007 Jan 29.
- Oct-3/4 encoded by Pou5f1 has been longwise recognised as a gatekeeper for embryonic stem (ES) cell pluripotency. Recently, it was suggested that Oct-3/4 one of the earliest transcription factor of the embryo might feature some functions in differentiation of cell lineages. We recently uncovered a k
- PMID 17245123
Japanese Journal
- 有限要素法による通電加熱における温度分布の解析
- 日本食品科学工学会誌 : Nippon shokuhin kagaku kogaku kaishi = Journal of the Japanese Society for Food Science and Technology 43(5), 510-519, 1996-05-15
- NAID 10007582055
- レタス個葉における非等方的生長の画像解析 葉の形状に対する温度効果について
- 生物環境調節 29(3), 141-145, 1991
- NAID 130003879509
- 鱗翅類の染色体について
- 蝶と蛾 32(1,2), 13-28, 1981-09-20
- NAID 110007707809
Related Links
- 2011年8月3日 ... “LONGWISE （ロングワイズ？）” こんな記事は、書きたくないのですが・・・、最低の下っ てあるんですね！ タグ・サイクリングサービスでは、通販や他店でお買い求めの自転車 の再組立て再調整も受付けていますが、この、LONGWISEという ...
Related Pictures
