English Journal

How Protective Mechanisms Interact to Prevent Overnight Calcium Phosphate Precipitation - An Observational Study to Determine Factors Against Calcium Phosphate Lithogenesis in a Healthy Cohort.

Shafiee MA1, Logan AG, Halperin ML.
Nephron.Nephron.2016 Feb 19. [Epub ahead of print]
BACKGROUND/AIMS: As restful, non-interrupted sleep is essential for normal mental and physical functioning, the urine flow rate (UFR) overnight remains low. Due to this reduced UFR, the kidneys produce a lower urine volume, which may lead to supersaturation of lithogens in the renal collecting syste
PMID 26890695

Clifford-Mobley O1, Sjögren A2, Lindner E2, Rumsby G3.
Urolithiasis.Urolithiasis.2016 Feb 8. [Epub ahead of print]
Hyperoxaluria is a well-recognised risk factor for urolithiasis and patients with primary hyperoxaluria (PH) gradually build up calcium oxalate deposits leading to chronic kidney disease. Efforts to improve treatment for PH have focused on reducing urine oxalate excretion and thus decreasing lithoge
PMID 26857252

Development of Endoplasmic Reticulum Stress during Experimental Oxalate Nephrolithiasis.

Motin YG1, Lepilov AV2, Bgatova NP3, Zharikov AY2, Motina NV2, Lapii GA4, Lushnikova EL4, Nepomnyashchikh LM4.
Bulletin of experimental biology and medicine.Bull Exp Biol Med.2016 Jan;160(3):381-5. doi: 10.1007/s10517-016-3176-x. Epub 2016 Jan 11.
Morphological and ultrastructural study of the kidney was performed in rats with oxalate nephrolithiasis. Specific features of endoplasmic reticulum stress were evaluated during nephrolithiasis and treatment with α-tocopherol. We observed the signs of endoplasmic reticulum stress with activation of
PMID 26750932

Japanese Journal

村田暁彦,小山基,木村寛,西村顕正,久保寛仁,佐々木睦男
日本臨床外科学会雑誌 = The journal of the Japan Surgical Association 69(7), 1578-1584, 2008-07-25
骨盤内悪性腫瘍が隣接臓器に浸潤することはしばしば経験させられ，根治目的に合併切除を余儀なくされることも多い．特に，広範囲膀胱浸潤症例においては，膀胱全摘あるいは骨盤内臓全摘術が施行され，排尿機能の廃絶により，術後のQOLは著しく損なわれる．これまでに膀胱合併切除を施行されたのは51例である．そのうち，膀胱を広範囲に切除した膀胱浸潤大腸癌8例，卵巣癌・子宮肉腫各1例の計10例に対し，膀胱拡大術を施行 …
NAID 10021944348

Expression Profiles of MUC Mucin Core Protein in the Intrahepatic Biliary System : Physiological Distribution and Pathological Significance

Sasaki Motoko,Ikeda Hiroko,Nakanuma Yasuni
Acta histochemica et cytochemica = Official Journal of the Japan Society of Histochemistry and Cytochemistry 38(5), 295-303, 2005
… In hepatolithiasis, MUC5AC (gastric foveolar epithelial type) and MUC6 (pyloric gland type) mucins are newly expressed in surface epithelial cells and proliferated peribiliary glands, respectively, and the expression of gel-forming mucin may play a role in lithogenesis. …
NAID 110003502638

Expression of deleted in malignant brain tumor-1 (DMBT1) molecule in biliary epithelium is augmented in hepatolithiasis : possible participation in lithogenesis