WordNet

a drug that neutralizes or counteracts the effects of another drug
a muscle that relaxes while another contracts; "when bending the elbow the triceps are the antagonist"
a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

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Chronic nasal dysfunction in children: Allergic rhinitis? Infectious? What to do if neither?

Wei JL1.
Current opinion in otolaryngology & head and neck surgery.Curr Opin Otolaryngol Head Neck Surg.2015 Oct 20. [Epub ahead of print]
PURPOSE OF REVIEW: To review challenges in the diagnosis, work-up, and management of healthy children who present to the otolaryngologist with nasal dysfunction. Common symptoms include chronic nasal congestion, with or without rhinorrhea, with or without previous empirically treated 'allergic rhini
PMID 26488532

Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children.

Brodlie M1, Gupta A, Rodriguez-Martinez CE, Castro-Rodriguez JA, Ducharme FM, McKean MC.
The Cochrane database of systematic reviews.Cochrane Database Syst Rev.2015 Oct 19;10:CD008202. [Epub ahead of print]
BACKGROUND: Episodic viral wheeze (EVW) associated with viral respiratory tract infections is a common reason for pre-school children to utilise health care resources and for carers to take time away from employment. About a third of children experience a wheezing episode before the age of five year
PMID 26482324

Effects of ONO-6950, a novel dual cysteinyl leukotriene 1 and 2 receptors antagonist, in a guinea pig model of asthma.

Yonetomi Y1, Sekioka T2, Kadode M2, Kitamine T2, Kamiya A2, Inoue A2, Nakao T2, Nomura H2, Murata M2, Nakao S2, Nambu F2, Fujita M2, Nakade S2, Kawabata K2.
European journal of pharmacology.Eur J Pharmacol.2015 Oct 15;765:242-8. doi: 10.1016/j.ejphar.2015.08.041. Epub 2015 Aug 28.
We assessed in this study the anti-asthmatic effects of ONO-6950, a novel cysteinyl leukotriene 1 (CysLT1) and 2 (CysLT2) receptors dual antagonist, in normal and S-hexyl glutathione (S-hexyl GSH)-treated guinea pigs, and compared these effects to those of montelukast, a CysLT1 selective receptor an
PMID 26318198

Kuraishi Yasushi
Biological and Pharmaceutical Bulletin 36(8), 1228-1234, 2013
… include receptors (histamine H4 receptor, leukotriene B4 receptors, interleukin-31 receptor A, bombesin BB2 receptor, toll-like receptor 3, α-adrenoceptor, and opioid μ- and κ-receptors), channels (transient receptor potential (TRP) V3 and TRPA1 channels), and enzymes (histidine decarboxylase, sphingomyelin glucosylceramide deacylase, 5-lipoxygenase, leukotriene A4 hydrolase, and …
NAID 130003361502

E1-1 Relation of allergic rhinitis and exercise-induced bronchoconstriction reffering to use of inhaled corticosteroids and leukotriene receptor antagonists : a cross-sectional study(English Session 1)