キネチン、カイネチン
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/11/10 22:09:50」(JST)
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"Carlos Miller" redirects here. For the American comedian, see Karlous Miller.
Kinetin
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Names |
IUPAC name
N6-furfuryladenine
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Identifiers |
CAS Number
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525-79-1 Y |
ChEBI |
CHEBI:27407 N |
ChemSpider |
3698= N |
ECHA InfoCard |
100.007.622 |
EC Number |
208-382-2 |
Jmol 3D model |
Interactive image |
KEGG |
C08272 N |
PubChem |
3830 |
RTECS number |
AU6270000 |
UNII |
P39Y9652YJ Y |
InChI
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InChI=1S/C10H9N5O/c1-2-7(16-3-1)4-11-9-8-10(13-5-12-8)15-6-14-9/h1-3,5-6H,4H2,(H2,11,12,13,14,15) N
Key: QANMHLXAZMSUEX-UHFFFAOYSA-N N
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SMILES
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C(Nc1ncnc2nc[nH]c12)c1ccco1
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Properties |
Chemical formula
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C10H9N5O |
Molar mass |
215.22 g·mol−1 |
Appearance |
Off-white amorphous powder |
Melting point |
269–271 °C (516–520 °F; 542–544 K) (decomposes) |
Structure |
Crystal structure
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cubic |
Hazards |
S-phrases |
S22 S24/25 |
Related compounds |
Related
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cytokinin |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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N verify (what is YN ?) |
Infobox references |
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Kinetin[pronunciation?] is a type of cytokinin, a class of plant hormone that promotes cell division. Kinetin was originally isolated by Miller[1] and Skoog et al.[2] as a compound from autoclaved herring sperm DNA that had cell division-promoting activity. It was given the name kinetin because of its ability to induce cell division, provided that auxin was present in the medium. Kinetin is often used in plant tissue culture for inducing formation of callus (in conjunction with auxin) and to regenerate shoot tissues from callus (with lower auxin concentration).
For a long time, it was believed that kinetin was an artifact produced from the deoxyadenosine residues in DNA, which degrade on standing for long periods or when heated during the isolation procedure. Therefore, it was thought that kinetin does not occur naturally, but, since 1996, it has been shown by several researchers that kinetin exists naturally in the DNA of cells of almost all organisms tested so far, including human and various plants. The mechanism of production of kinetin in DNA is thought to be via the production of furfural — an oxidative damage product of deoxyribose sugar in DNA — and its quenching by the adenine base's converting it into N6-furfuryladenine, kinetin.
Kinetin is also widely used in producing new plants from tissue cultures.
History
In 1939 P. A. C. Nobécourt (Paris) began the first permanent callus culture from root explants of carrot (Daucus carota). Such a culture can be kept forever by successive transplantations onto fresh nutrient agar.[citation needed] The transplantations occur every three to eight weeks. Callus cultures are not cell cultures, since whole tissue associations are cultivated. Though many cells keep their ability to divide, this is not true for all. One reason for this is the aneuploidy of the nuclei and the resultant unfavourable chromosome constellations.[citation needed]
In 1941 J. van Overbeek (Rijksuniversiteit Utrecht) introduced coconut milk as a new component of nutrient media for callus cultures.[3] Coconut milk is liquid endosperm. It stimulates the embryo to grow when it is supplied with food at the same time. Results yielded from callus cultures showed that its active components stimulate the growth of foreign cells too.
In 1954 F. Skoog (University of Wisconsin, Madison) developed a technique for the generation and culture of wound tumor tissue from isolated shoot parts of tobacco (Nicotiana tabacum).[citation needed] The developing callus grows when supplied with yeast extract, coconut milk, or old DNA preparations. Freshly prepared DNA has no effect but becomes effective after autoclaving. This led to the conclusion that one of its breakdown products is required for cell growth and division. The substance was characterized, was given the name kinetin, and classified as a phytohormone.
See also
References
- ^ Schwartz, Dale. "Carlos O. Miller" (pdf). Retrieved 15 November 2011.
- ^ Amasino, R. (2005). "1955: Kinetin Arrives. The 50th Anniversary of a New Plant Hormone". Plant Physiology. 138 (3): 1177–1184. doi:10.1104/pp.104.900160. PMC 1176392. PMID 16009993.
- ^ Van Overbeek, J.; Conklin, M. E.; Blakeslee, A. F. (1941). "Factors in Coconut Milk Essential for Growth and Development of Very Young Datura Embryos". Science. 94 (2441): 350–1. doi:10.1126/science.94.2441.350. PMID 17729950.
- Mok, David W.S.; Mok, Machteld C., eds. (1994). Cytokinins: chemistry, activity and function. Boca Raton, FL: CRC Press. ISBN 978-0-8493-6252-1.
- Barciszewski, J.; Siboska, G. E.; Pedersen, B. O.; Clark, B. F.; Rattan, S. I. (1996). "Evidence for the presence of kinetin in DNA and cell extracts". FEBS Letters. 393 (2–3): 197–200. doi:10.1016/0014-5793(96)00884-8. PMID 8814289.
- Barciszewski, J.; Rattan, S. I. S.; Siboska, G.; Clark, B. F. C. (1999). "Kinetin — 45 years on". Plant Science. 148: 37. doi:10.1016/S0168-9452(99)00116-8.
- Rattan, S. I. S.; Clark, B. F. C. (1994). "Kinetin Delays the Onset of Aging Characteristics in Human Fibroblasts". Biochemical and Biophysical Research Communications. 201 (2): 665–672. doi:10.1006/bbrc.1994.1752. PMID 8003000.
- Rattan, S. I. S. (2002). "N6-Furfuryladenine (Kinetin) as a Potential Anti-Aging Molecule". Journal of Anti-Aging Medicine. 5: 113–111. doi:10.1089/109454502317629336.
- Hertz, Nicholas T.; Berthet, Amandine; Sos, Martin L.; Thorn, Kurt S.; Burlingame, Al L.; Nakamura, Ken; Shokat, Kevan M. "A Neo-Substrate that Amplifies Catalytic Activity of Parkinson's-Disease-Related Kinase PINK1". Cell. 154 (4): 737–747. doi:10.1016/j.cell.2013.07.030.
English Journal
- Hormonal and metabolic regulation of tomato fruit sink activity and yield under salinity.
- Albacete A1, Cantero-Navarro E2, Balibrea ME2, Großkinsky DK3, de la Cruz González M4, Martínez-Andújar C2, Smigocki AC5, Roitsch T6, Pérez-Alfocea F7.
- Journal of experimental botany.J Exp Bot.2014 Nov;65(20):6081-95. doi: 10.1093/jxb/eru347. Epub 2014 Aug 28.
- Salinization of water and soil has a negative impact on tomato (Solanum lycopersicum L.) productivity by reducing growth of sink organs and by inducing senescence in source leaves. It has been hypothesized that yield stability implies the maintenance or increase of sink activity in the reproductive
- PMID 25170099
- Genetic and epigenetic uniformity of polyembryony derived multiple seedlings of Hevea brasiliensis.
- Karumamkandathil R1, Uthup TK, Sankaran S, Unnikrishnan D, Saha T, Nair SS.
- Protoplasma.Protoplasma.2014 Oct 31. [Epub ahead of print]
- Hevea brasiliensis Muell. Arg (Para rubber tree) is a tropical tree species of Amazonian origin widely cultivated in several parts of the world for natural rubber, a highly priced commodity inevitable for the world rubber industry. Large, tree to tree variation in growth and latex yield among indivi
- PMID 25359186
- [Effect of kinetin on immunity and splenic lymphocyte proliferation in vitro in D-galactose-induced aging rats].
- Li MY1, Ouyang WQ, Wu XL, Zheng Y, Gao R, Tang JX.
- Sheng li xue bao : [Acta physiologica Sinica].Sheng Li Xue Bao.2014 Oct 25;66(5):605-11.
- The purpose of this paper is to study the effect of kinetin (Kn) on immunity and splenic lymphocyte proliferation in vitro of aging rats induced by D-galactose (D-gal). Fifty SD rats were randomly divided into five groups: control group, aging model group, Kn low dose group, Kn middle dose group and
- PMID 25332007
Japanese Journal
- Efficient plant regeneration system from seed-derived callus of ravenna grass [Erianthus ravennae (L.) Beauv.]
- Shimomae Kazuki,Chin Dong Poh,Khan Raham Sher [他],Mii Masahiro
- Plant Biotechnology 30(5), 473-478, 2013
- … By using these 3 types of calli, effects of different concentrations of BA or 6-furfurylaminopurine (kinetin) (0, 0.1, 0.5, 1, 2 and 4 mg l−1) and naphthaleneacetic acid (NAA) (0, 0.25, 0.5 and 1 mg l−1) as plant growth regulators on shoot regeneration were evaluated using MS medium with 1 g l−1 casamino acids as a basal medium. …
- NAID 130003382497
- Effects of Medium Components and Shear Conditions on the Formation and Growth of Adventitious Bud Derived from Hairy Roots of Atropa belladonna L.
- MERA Nobuaki,TAKAYAMA Shinsaku
- Environment control in biology 50(4), 393-406, 2012-12-30
- … Various concentrations of kinetin (KN) alone were prepared in combination with Murashige and Skoog (MS) and Gamborg's B5 (B5) media. …
- NAID 10031136576
- Evaluation of some therapies and meristem culture to eliminate Potato Y potyvirus from infected potato plants
- AlMaarri K.,Massa R.,AlBiski F.
- Plant biotechnology 29(3), 237-243, 2012-06-25
- … Meristems (length 100, 200, 300 µm) were excised from infected Potato plants of Binella and Burren cultivars and cultured on solidified MS medium containing 30 g l-1 sucrose, 5 mg l-1 Ascorbic acid, 5 mg l-1 Pyridoxine, 5 mg l-1 Nicotinic acid, 5 mg l-1 Thiamine, 200 mg l-1 Inositole, 2 mg l-1 GA3, and 0.2 mg l-1 kinetin. …
- NAID 10030804590
Related Links
- [Kinetin] [525-79-1] | 価格や在庫、物性値などの詳細情報ページです。 ... ・川口の在庫は即日,つくばの在庫は2〜3日以内の出荷となります。・詳細につきましては,お手数ですが営業部までお問い合わせください。
- カイネチン【kinetin】とは。意味や解説。植物の細胞分裂を促進する物質。サイトカイニンの一種。キネチン。 - goo辞書は国語、英和、和英、中国語、百科事典等からまとめて探せる辞書検索サービスです。
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