| Keratosis pilaris |
| Classification and external resources |
Keratosis pilaris rubra on a right upper arm. |
| ICD-9 |
757.39 |
| OMIM |
604093 |
| DiseasesDB |
32387 |
| MedlinePlus |
001462 |
| eMedicine |
ped/1246 derm/211 |
Keratosis pilaris (KP, also follicular keratosis or chicken skin) is a common, autosomal dominant, genetic follicular condition that is manifested by the appearance of rough, slightly red, bumps on the skin. It most often appears on the back and outer sides of the arm (though the forearm can also be affected), and can also occur on the thighs, hands, and tops of legs, sides, buttocks, or any body part except glabrous skin (like the palms or soles of feet).[1] Less commonly, lesions appear on the face, which may be mistaken for acne.[2]
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Contents
- 1 Classification
- 2 Symptoms and signs
- 3 Treatments
- 4 See also
- 5 References
- 6 External links
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Classification
Worldwide, KP affects an estimated 40% of the adult population and approximately 50%-80% of all adolescents. It is more common in women than in men.[3]
There are several different types of keratosis pilaris, including keratosis pilaris rubra (red, inflamed bumps which can be on arms, head, legs), keratosis pilaris alba (rough, bumpy skin with no irritation), keratosis pilaris rubra faceii (reddish rash on the cheeks), and related disorders.
While KP resembles goose bumps, it is characterized by the appearance of small rough reddish bumps on the skin. As a result, many people with keratosis pilaris do not know they have it, and it is often confused with acne.[4]
Symptoms and signs
Keratosis pilaris occurs when the human body produces excess keratin, a natural protein in the skin. The excess keratin, which is cream colored, surrounds and entraps the hair follicles in the pore. This causes the formation of hard plugs (process known as hyperkeratinization). Bearing only cosmetic consequence, the condition most often appears as a proliferation of tiny hard bumps that are seldom sore or itchy. Though people with keratosis pilaris experience this condition year-round, it is during the colder months, when moisture levels in the air are lower, that the problem can become exacerbated and the goose bumps are apt to look and feel more pronounced in color and texture.[citation needed]
Many KP bumps contain an ingrown hair that has coiled. This is a result of the keratinized skin's "capping off" the hair follicle, preventing the hair from exiting. The hair grows encapsulated inside the follicle.
Treatments
Treatments for Keratosis pilaris may consist of moisturizing or keratolytic treatments including: urea, lactic acid, salicylic acid, or topical retinoids. However, the effectiveness of these treatments is limited and research to discover more efficacious treatments is needed.[5]
See also
- Ichthyosis linearis circumflexa
- List of cutaneous conditions
References
- ^ Alai, Nili. "Keratosis Pilaris (KP)". MedicineNet. http://www.medicinenet.com/keratosis_pilaris/article.htm. Retrieved 2008-10-06.
- ^ Berman, Kevin. "Keratosis pilaris". MedlinePlus. http://www.nlm.nih.gov/medlineplus/ency/article/001462.htm. Retrieved 2008-06-19.
- ^ Alai, Nili; Arash Michael Saemi,Raul Del Rosario. "Keratosis Pilaris". eMedicine. http://www.emedicine.com/derm/topic211.htm. Retrieved 2008-19-20.
- ^ Smith, Karen (Nov. 2008). "Keratosis Pilaris, KP, Chicken Skin". Keratosis Pilaris Help. http://www.helpforkp.com/. Retrieved 2008-11-10.
- ^ Park, Juhee; Kim, Beom J; Kim, Myeung N; Lee, Chang K (2011). "A Pilot Study of Q-switched 1064-nm Nd:YAG Laser Treatment in the Keratosis Pilaris". Annals of Dermatology 23 (3): 293-298. doi:10.5021/ad.2011.23.3.293.
External links
- The American Osteopathic College of Dermatology - Article on keratosis pilaris
- Keratosis Pilaris :Help for KP - Information on keratosis pilaris
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Congenital malformations and deformations of integument / skin disease (Q80–Q82, 757.0–757.3)
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| Genodermatosis |
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Congenital ichthyosis/
erythrokeratodermia
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AD
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Ichthyosis vulgaris
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AR
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Congenital ichthyosiform erythroderma: Epidermolytic hyperkeratosis · Lamellar ichthyosis (Harlequin type ichthyosis)
Netherton syndrome · Zunich–Kaye syndrome · Sjögren–Larsson syndrome
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XR
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X-linked ichthyosis
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Ungrouped
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Ichthyosis bullosa of Siemens · Ichthyosis follicularis · Ichthyosis prematurity syndrome · Ichthyosis–sclerosing cholangitis syndrome · Nonbullous congenital ichthyosiform erythroderma · Ichthyosis linearis circumflexa · Ichthyosis hystrix
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EB
and related
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EBS (EBS-K, EBS-WC, EBS-DM, EBS-OG, EBS-MD, EBS-MP)
JEB (JEB-H, Mitis, Generalized atrophic, JEB-PA)
DEB (DDEB, RDEB)
related: Costello syndrome · Kindler syndrome · Laryngoonychocutaneous syndrome · Skin fragility syndrome ·
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Ectodermal dysplasia
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Naegeli syndrome/Dermatopathia pigmentosa reticularis · Hay–Wells syndrome · Hypohidrotic ectodermal dysplasia · Focal dermal hypoplasia · Ellis–van Creveld syndrome · Rapp–Hodgkin syndrome/Hay–Wells syndrome
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Elastic/Connective
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Ehlers–Danlos syndrome · Cutis laxa (Gerodermia osteodysplastica) · Popliteal pterygium syndrome · Pseudoxanthoma elasticum · Van Der Woude syndrome
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Hyperkeratosis/
keratinopathy
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PPK
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diffuse: Diffuse epidermolytic palmoplantar keratoderma • Diffuse nonepidermolytic palmoplantar keratoderma • Palmoplantar keratoderma of Sybert • Mal de Meleda •
syndromic (connexin (Bart–Pumphrey syndrome • Clouston's hidrotic ectodermal dysplasia • Vohwinkel syndrome) • Corneodermatoosseous syndrome • plakoglobin (Naxos syndrome) • Scleroatrophic syndrome of Huriez • Olmsted syndrome • Cathepsin C (Papillon–Lefèvre syndrome • Haim–Munk syndrome) • Camisa disease
focal: Focal palmoplantar keratoderma with oral mucosal hyperkeratosis • Focal palmoplantar and gingival keratosis • Howel–Evans syndrome • Pachyonychia congenita (Pachyonychia congenita type I • Pachyonychia congenita type II) • Striate palmoplantar keratoderma • Tyrosinemia type II)
punctate: Acrokeratoelastoidosis of Costa • Focal acral hyperkeratosis • Keratosis punctata palmaris et plantaris • Keratosis punctata of the palmar creases • Schöpf–Schulz–Passarge syndrome • Porokeratosis plantaris discreta • Spiny keratoderma
ungrouped: Palmoplantar keratoderma and spastic paraplegia • desmoplakin (Carvajal syndrome) • connexin (Erythrokeratodermia variabilis • HID/KID)
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Other
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Meleda disease · Keratosis pilaris · ATP2A2 (Darier's disease) · Dyskeratosis congenita · Lelis syndrome
Dyskeratosis congenita · Keratolytic winter erythema · Keratosis follicularis spinulosa decalvans · Keratosis linearis with ichthyosis congenital and sclerosing keratoderma syndrome · Keratosis pilaris atrophicans faciei · Keratosis pilaris
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Other
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cadherin (EEM syndrome) · immune system (Hereditary lymphedema, Mastocytosis/Urticaria pigmentosa) · Hailey–Hailey
see also Template:Congenital malformations and deformations of skin appendages, Template:Phakomatoses, Template:Pigmentation disorders, Template:DNA replication and repair-deficiency disorder
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Developmental
anomalies |
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Midline
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Dermoid cyst · Encephalocele · Nasal glioma · PHACE association · Sinus pericranii
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Nevus
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Capillary hemangioma · Port-wine stain (Nevus flammeus nuchae)
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Other/ungrouped
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Aplasia cutis congenita · Amniotic band syndrome · Branchial cyst · Cavernous venous malformation
Accessory nail of the fifth toe · Bronchogenic cyst · Congenital cartilaginous rest of the neck · Congenital hypertrophy of the lateral fold of the hallux · Congenital lip pit · Congenital malformations of the dermatoglyphs · Congenital preauricular fistula · Congenital smooth muscle hamartoma · Cystic lymphatic malformation · Median raphe cyst · Melanotic neuroectodermal tumor of infancy · Mongolian spot · Nasolacrimal duct cyst · Omphalomesenteric duct cyst · Poland anomaly · Rapidly involuting congenital hemangioma · Rosenthal–Kloepfer syndrome · Skin dimple · Superficial lymphatic malformation · Thyroglossal duct cyst · Verrucous vascular malformation · Birthmark
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noco(i/b/d/q/u/r/p/m/k/v/f)/cong/tumr(n/e/d), sysi/epon
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proc, drug (D2/3/4/5/8/11)
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