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1. GISTを含む消化管間葉系腫瘍の疫学、分類、臨床像、予後の特徴、および診断方法 epidemiology classification clinical presentation prognostic features and diagnostic work up of gastrointestinal mesenchymal neoplasms including gist

English Journal

N-terminally truncated forms of human cathepsin F accumulate in aggresome-like inclusions.

Jerič B, Dolenc I, Mihelič M, Klarić M, Zavašnik-Bergant T, Gunčar G, Turk B, Turk V, Stoka V.SourceDepartment of Biochemistry and Molecular and Structural Biology, J. Stefan Institute, Jamova 39, SI-1000 Ljubljana, Slovenia; Jožef Stefan International Postgraduate School, Jamova 39, SI-1000 Ljubljana, Slovenia.
Biochimica et biophysica acta.Biochim Biophys Acta.2013 Oct;1833(10):2254-66. doi: 10.1016/j.bbamcr.2013.05.007. Epub 2013 May 14.
The contribution of individual cysteine cathepsins as positive mediators of programmed cell death is dependent on several factors, such as the type of stimuli, intensity and duration of the stimulus, and cell type involved. Of the eleven human cysteine cathepsins, cathepsin F is the only cathepsin t
PMID 23684953

Endosomal trafficking of open Major Histocompatibility Class I conformers--implications for presentation of endocytosed antigens.

Mahmutefendić H, Zagorac GB, Tomaš MI, Groettrup M, Momburg F, Lučin P.SourceUniversity of Rijeka, Faculty of Medicine, Department of Physiology and Immunology, Rijeka, Croatia.
Molecular immunology.Mol Immunol.2013 Sep;55(2):149-52. doi: 10.1016/j.molimm.2012.10.008. Epub 2012 Nov 27.
Major Histocompatibility Class I (MHC-I) molecules are present at the cell surface either as fully conformed trimolecular complexes composed of heavy chain, beta-2-microglobulin (β2m) and antigenic peptide or as various open forms, devoid of the peptide and/or β2m. While the role of fully conforme
PMID 23200229

The endosomal pathway and the Golgi complex are involved in the infectious bursal disease virus life cycle.

Delgui LR, Rodríguez JF, Colombo MI.SourceLaboratorio de Biología Celular y Molecular, Instituto de Histología y Embriología de Mendoza, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo-CONICET, Mendoza, Argentina.
Journal of virology.J Virol.2013 Aug;87(16):8993-9007. doi: 10.1128/JVI.03152-12. Epub 2013 Jun 5.
Infectious bursal disease virus (IBDV), a double-stranded RNA virus belonging to the Birnaviridae family, causes immunosuppression in chickens. In this study, we defined the localization of IBDV replication complexes based on colocalization analysis of VP3, the major protein component of IBDV ribonu
PMID 23741000

Spontaneous Subcutaneous Sarcoma in a 50-week-old Male Wistar Hannover GALAS Rat

Onozato Tomoya,Tamura Toru,Nagasawa Tatsuya,Hayashi Morimichi,Okuhara Yuji,Kuroda Junji
Journal of Toxicologic Pathology 24(4), 239-244, 2011
… Argentophilic thin fibers were observed to wrap up the individual cells, and some of the tumor cells showed coexpression of vimentin and cytokeratin that formed juxtanuclear globes in the cytoplasm by double immunohistostaining. …
NAID 130001884728

Seven Kinds of Intermediate Filament Networks in the Cytoplasm of Polarized Cells: Structure and Function

Iwatsuki Hirohiko,Suda Masumi
ACTA HISTOCHEMICA ET CYTOCHEMICA 43(2), 19-31, 2010
… We have clarified the existence of seven kinds of IF networks in the cytoplasm of diverse polarized cells: an apex network just under the terminal web, a peripheral network lying just beneath the cell membrane, a granule-associated network surrounding a mass of secretory granules, a Golgi-associated network surrounding the Golgi apparatus, a radial network locating from the perinuclear region to the specific area of the cell membrane, a juxtanuclear network surrounding the nucleus, and an entire cytoplasmic network. …
NAID 130000248639

Iwatsuki Hirohiko,Suda Masumi
Acta histochemica et cytochemica = Official Journal of the Japan Society of Histochemistry and Cytochemistry 40(1-6), 123-130, 2007
… In the enteroendocrine cells, keratin 20-containing filaments formed a juxtanuclear network from which they extended to the apical cell membrane. …
NAID 110006633422