WordNet
- any of the small tubules that are the excretory units of the vertebrate kidney (同)uriniferous_tubule
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/11/07 21:08:42」(JST)
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Juxtamedullary nephron |
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Nephron of the kidney without juxtaglomerular apparatus |
Precursor |
Metanephric blastema |
A juxtamedullary nephron is a type of nephron, found only in birds and mammals and not in other vertebrates. The "medullary" is referring to the renal medulla, while the "juxta", (Latin: near), refers to the relative position of the renal corpuscle, which in these nephrons is near the medulla. In other words, a "juxtamedullary nephron" is one where the renal corpuscle is close to the medulla, and the proximal convoluted tubule and its associated loop of Henle occur at a deep position compared to most other nephrons.
This type of nephron is relatively rare, and only comprise 20-30% of the nephrons in the human kidney. However, in most depictions of the nephron, it is a juxtamedullary nephron which is depicted. The greater gradient in the deep medulla make this type of nephron do more "work" than more shallow nephrons, and their vertical nature makes them easier to illustrate. It is these nephrons which are responsible for the development of the osmotic gradients in the renal medulla, which are used to concentrate urine.
External links
- Physiology at MCG 7/7ch03/7ch03p16
- Diagram at mcgill.ca
- Diagram at clinic-clinic.com (Juxtamedullary at left)
UpToDate Contents
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English Journal
- Immunosuppression preserves renal autoregulatory function and microvascular P2X1 receptor reactivity in ANG II-hypertensive rats.
- Guan Z, Giddens MI, Osmond DA, Cook AK, Hobbs JL, Zhang S, Yamamoto T, Pollock JS, Pollock DM, Inscho EW.SourceDept. of Physiology, Georgia Health Sciences Univ., 1120, 15th St., Augusta, GA 30912. einscho@gru.edu.
- American journal of physiology. Renal physiology.Am J Physiol Renal Physiol.2013 Mar;304(6):F801-7. doi: 10.1152/ajprenal.00286.2012. Epub 2012 Dec 26.
- Autoregulation is critical for protecting the kidney against arterial pressure elevation and is compromised in some forms of hypertension. Evidence indicates that activated lymphocytes contribute importantly to cardiovascular injury in hypertension. We hypothesized that activated lymphocytes contrib
- PMID 23269644
- Albuminuria indicates the pressure-associated injury of juxtamedullary nephrons and cerebral strain vessels in spontaneously hypertensive stroke-prone rats.
- Nagasawa T, Mori T, Ohsaki Y, Yoneki Y, Guo Q, Sato E, Oba I, Ito S.SourceDivision of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
- Hypertension research : official journal of the Japanese Society of Hypertension.Hypertens Res.2012 Oct;35(10):1024-31. doi: 10.1038/hr.2012.112. Epub 2012 Aug 23.
- Albuminuria is an indicator of renal injury and is closely linked with cardiovascular disease (CVD). However, the mechanism by which albumin is excreted in the urine remains unclear. As the juxtamedullary region of the kidney is highly susceptible to pressure increase, juxtamedullary injury is obser
- PMID 22914555
Japanese Journal
- Role of Interstitial ATP and Adenosine in the Regulation of Renal Hemodynamics and Microvascular Function
- Hypertension research : clinical and experimental : official journal of the Japanese Society of Hypertension 27(11), 791-804, 2004-11-01
- NAID 10014387419
- 薬物腎排泄に関わる有機カチオントランスポータ(OCT)の分子的多様性
- 藥學雜誌 = Journal of the Pharmaceutical Society of Japan 122(11), 957-965, 2002-11-01
- NAID 10010204285
- ラットネフロンにおける旁糸球体顆粒消長の生理的意義について
Related Links
- juxtamedullary nephron, one whose proximal convoluted tubule is close to the corticomedullary border and whose loop of Henle extends deep into the renal medulla. ... Disclaimer All content on this website, including dictionary ...
- juxtamedullary nephron, one whose proximal convoluted tubule is close to the corticomedullary border and whose loop of Henle extends deep into the renal medulla. ... Disclaimer All content on this website, including dictionary ...
Related Pictures
★リンクテーブル★
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- 英
- juxta-medullary nephron(SP), juxtamedullary nephron (Z)
- 同
- 髄傍ネフロン、深在ネフロン、長ループネフロン
- 関
- 皮質ネフロン
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- 英
- juxtamedullary nephron
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