- 関
- syngeneic transplantation
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/06/17 23:25:14」(JST)
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An Isograft is a graft of tissue between two individuals who are genetically identical (i.e. monozygotic twins). Transplant rejection between two such individuals virtually never occurs.
As monozygotic twins have the same major histocompatibility complex, there is very rarely any rejection of transplanted tissue by the adaptive immune system. Furthermore, there is virtually no incidence of graft-versus-host disease. This forms the basis for why the preferred choice of a physician considering an organ donor will be a monozygotic twin.
In 1993 a research article demonstrated that islet isografts were being transplanted into young diabetic mice [STZ induced diabetic NOD mice] and the mice survived atleast about 22 days post transplantation.
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References
- ^ http://diabetes.diabetesjournals.org/content/42/2/324.full.pdf+html
UpToDate Contents
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English Journal
- Comparative study of the efficacy of decellularization treatment of allogenic and xenogeneic nerves as nerve conduits.
- Wang W1, Itoh S1,2, Takakuda K1.
- Journal of biomedical materials research. Part A.J Biomed Mater Res A.2015 Oct 16. doi: 10.1002/jbm.a.35589. [Epub ahead of print]
- The objective of this study was to compare the results of allogenic and xenogeneic nerve grafts that were treated using decellularization. The sciatic nerves of Sprague-Dawley rats and the median nerves of Japanese white rabbits were decellularized with sodium dodecyl sulfate and Triton X-100 and ex
- PMID 26474327
- A glial cell line-derived neurotrophic factor delivery system enhances nerve regeneration across acellular nerve allografts.
- Tajdaran K1, Gordon T2, Wood MD3, Shoichet MS4, Borschel GH5.
- Acta biomaterialia.Acta Biomater.2015 Oct 9. pii: S1742-7061(15)30133-1. doi: 10.1016/j.actbio.2015.10.001. [Epub ahead of print]
- Acellular nerve allografts (ANAs) are used clinically to bridge nerve gaps but these grafts, lacking Schwann cells and therapeutic levels of neurotrophic factors, do not support regeneration to the same extent as autografts. Here we investigated a local drug delivery system (DDS) for glial cell line
- PMID 26441127
- Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer.
- Stewart MK1, Bechberger JF2, Welch I3, Naus CC2, Laird DW1,4.
- Oncotarget.Oncotarget.2015 Oct 2. [Epub ahead of print]
- Down-regulation of the gap junction protein connexin26 (Cx26) is an early event following breast cancer onset and has led to Cx26 being classically described as a tumor suppressor. Interestingly, mutations in theCx26 gene (GJB2) reduce or ablate Cx26 gap junction channel function and are the most co
- PMID 26439696
Japanese Journal
- Laser-Perforated Porous Nonwoven Chitosan Nerve Conduit
- RODOTHEOU Petros,WANG Wei,ITOH Soichiro,OKAZAKI Mutsumi,TAKAKUDA Kazuo
- Journal of Biomechanical Science and Engineering 8(2), 139-151, 2013
- … Twelve mm long grafts of following 4 groups (N=5, respectively) were implanted to rat sciatic nerve defects: non-pore, 2 lines of pores, 4 lines of pores and isograft. …
- NAID 130003366819
- Dental pulp can be a good candidate for nerve grafting in a xeno-graft model
- Matsushita Kazuhiro,Wang Wei,Itoh Soichiro,Domon Takanori,Funahashi Makoto,Totsuka Yasunori
- Journal of Neuroscience Methods 205(2), 246-251, 2012-04-15
- … As controls, chitosan tubes with and without sciatic nerve harvested from another SD rats were implanted (isograft group and tube group, respectively). … Thirty-two weeks after implantation, aggregation of axons was observed in this group and matched that in isograft group. … The average diameter of axons in dental pulp group was comparable to that in isograft group, whereas number of minifascicles and axon proportion were smaller. …
- NAID 120004027243
- Protective effect of FUT-175 on pulmonary function of xenografts in a guinea pig-to-rat lung perfusion model
- Ryu Chusei,Tagawa Tsutomu,Nagayasu Takeshi
- Acta Medica Nagasakiensia 56(2), 43-48, 2011-08
- … Methods: Animals were divided into three groups (n = 6 each), Isograft (Group I), Xenograft (Group X), and Xenograft with FUT-175 (Group XF). …
- NAID 110008767591
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- isograft / ˈaɪ səˌgræft, -ˌgrɑft / Show Spelled [ahy-s uh-graft, -grahft] Show IPA noun Surgery. syngraft. Origin: 1905–10; iso-+ graft 1 Dictionary.com Unabridged Based on the Random House Dictionary, © Random House, Inc. 2013.
Related Pictures
★リンクテーブル★
[★]
- 英
- isograft, isotransplantation, syngeneic transplantation, isotransplantation
- 同
- 同系移植片
- 関
- 移植、腫瘍移植
[★]
- 英
- isograft
- 関
- 同系移植
[★]
同系移植
- 関
- isograft