関: iotalamic acid、iothalamic acid

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/08/09 16:49:13」(JST)

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Iotalamic acid (also iothalamic acid in USAN) and its salts (INN Iothalamates) is an iodine-containing organic anion used as a radiocontrast agent. It is available as sodium iothalamate (Iothalamate sodium) and meglumine iothalamate (Iothalmate meglumine). It can be administered intravenously or intravesically (into the urinary bladder).^[1]

Radioactive formulation is also available as sodium iothalamate I-125 Injection (GLOFIL-125). It is indicated for evaluation of glomerular filtration in the diagnosis or monitoring of patients with renal disease.^[1]

References

^ ^a ^b "Iothalamate Meglumine and Iothalamate Sodium Drug Information, Professional". www.drugs.com. Retrieved 2016-07-16.

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English Journal

Tubular maximum phosphate reabsorption capacity in living kidney donors is independently associated with one year recipient GFR.

van Londen M1, Aarts BM2, Sanders JF2, Hillebrands JL3, Bakker SJL2, Navis G2, de Borst MH4.
American journal of physiology. Renal physiology.Am J Physiol Renal Physiol.2017 Oct 4:ajprenal.00287.2017. doi: 10.1152/ajprenal.00287.2017. [Epub ahead of print]
PMID 28978532

Acid Load and Phosphorus Homeostasis in CKD.

Khairallah P1, Isakova T2, Asplin J3, Hamm L4, Dobre M5, Rahman M5, Sharma K6, Leonard M7, Miller E 3rd8, Jaar B9, Brecklin C10, Yang W11, Wang X11, Feldman H12, Wolf M1, Scialla JJ13; Chronic Renal Insufficiency Cohort (CRIC) Study Investigators.
American journal of kidney diseases : the official journal of the National Kidney Foundation.Am J Kidney Dis.2017 Oct;70(4):541-550. doi: 10.1053/j.ajkd.2017.04.022. Epub 2017 Jun 21.
PMID 28645705

Autologous Mesenchymal Stem Cells Increase Cortical Perfusion in Renovascular Disease.

Saad A1, Dietz AB2, Herrmann SMS1, Hickson LJ1, Glockner JF3, McKusick MA4, Misra S4, Bjarnason H4, Armstrong AS2, Gastineau DA2, Lerman LO1, Textor SC5.
Journal of the American Society of Nephrology : JASN.J Am Soc Nephrol.2017 Sep;28(9):2777-2785. doi: 10.1681/ASN.2017020151. Epub 2017 May 1.
PMID 28461553

Japanese Journal

High performance liquid chromatographic measurement of iothalamate in human serum and urine for evaluation of glomerular filtration rate

BI Daoqin,LEARY Kevin J.,WEITZ Julie A.,CHERSTNIAKOVA Svetlana A.,REIL Michael A.,ROY Michael J.,CANTILENA Louis R.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 856(1), 95-99, 2007-09-01
NAID 10025807288

Simple HPLC-UV method for determination of iohexol, iothalamate p-aminohippuric acid and n-acetyl-p-aminohippuric acid in human plasma and urine with ERPF, GFR and ERPF/GFR ratio determination using colorimetric analysis

FARTHING Don,SICA Domenic A.,FAKHRY Itaf,LARUS Terri,GHOSH Sid,FARTHING Christine,VRANIAN Michael,GEHR Todd
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 826(1), 267-272, 2005-11-05
NAID 10017290522

「イオタラム酸」

Iotalamic acid
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	V08AA04 (WHO);
Identifiers
	IUPAC name 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid;
PubChem CID	3737;
ChemSpider	3606;
UNII	16CHD79MIX;
KEGG	D01258;
ECHA InfoCard	100.017.181
Chemical and physical data
Formula	C11H9I3N2O4
Molar mass	613.91357
3D model (JSmol)	Interactive image;
	SMILES CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NC)I ;
	InChI InChI=1S/C11H9I3N2O4/c1-3(17)16-9-7(13)4(10(18)15-2)6(12)5(8(9)14)11(19)20/h1-2H3,(H,15,18)(H,16,17)(H,19,20) ; Key:UXIGWFXRQKWHHA-UHFFFAOYSA-N ;