関: iothalamate、iothalamic acid

WordNet

street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
having the characteristics of an acid; "an acid reaction"

PrepTutorEJDIC

酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/11/27 18:37:44」(JST)

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Iotalamic acid (also iothalamic acid in USAN) and its salts (INN Iothalamates) is an iodine-containing organic anion used as a radiocontrast agent. It is available as sodium iothalamate (Iothalamate sodium) and meglumine iothalamate (Iothalmate meglumine). It can be administered intravenously or intravesically (into the urinary bladder).^[1]

Radioactive formulation is also available as sodium iothalamate I-125 Injection (GLOFIL-125). It is indicated for evaluation of glomerular filtration in the diagnosis or monitoring of patients with renal disease.^[1]

References

^ ^a ^b "Iothalamate Meglumine and Iothalamate Sodium Drug Information, Professional". www.drugs.com. Retrieved 2016-07-16.

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English Journal

HPLC estimation of iothalamate to measure glomerular filtration rate in humans.

Shah I1, Barker J2, Naughton DP2, Barton SJ2, Ashraf SS1.
Chemistry Central journal.Chem Cent J.2016 Dec 12;10:80. doi: 10.1186/s13065-016-0227-3. eCollection 2016.
Glomerular filtration rate (GFR) is usually determined by estimation of iothalamate (IOT) clearance. We have developed and validated an accurate and robust method for the analysis of IOT in human plasma and urine. The mobile phase consisted of methanol and 50 mM sodium phosphate (10:90; v/v). Flow
PMID 28028385

Whole-body diffusion-weighted magnetic resonance imaging in the diagnosis of recurrent ovarian cancer: a clinical feasibility study.

Michielsen KL1, Vergote I2, Dresen R1, Op de Beeck K1, Vanslembrouck R1, Amant F2,3, Leunen K2, Moerman P1, Fieuws S4, De Keyzer F1, Vandecaveye V1.
The British journal of radiology.Br J Radiol.2016 Nov;89(1067):20160468. Epub 2016 Sep 21.
OBJECTIVE: To assess the clinical feasibility of whole-body diffusion-weighted MRI (WB-DWI/MRI) for diagnosis and prediction of complete tumour resection in patients with suspected recurrent ovarian cancer.METHODS: 51 females clinically suspected for ovarian cancer recurrence underwent 3-T WB-DWI/MR
PMID 27585490

Photodecomposition of iodinated contrast media and subsequent formation of toxic iodinated moieties during final disinfection with chlorinated oxidants.

Allard S1, Criquet J2, Prunier A3, Falantin C4, Le Person A2, Yat-Man Tang J5, Croué JP3.
Water research.Water Res.2016 Oct 15;103:453-61. doi: 10.1016/j.watres.2016.07.050. Epub 2016 Jul 22.
Large amount of iodinated contrast media (ICM) are found in natural waters (up to μg.L(-)(1) levels) due to their worldwide use in medical imaging and their poor removal by conventional wastewater treatment. Synthetic water samples containing different ICM and natural organic matter (NOM) extracts
PMID 27498253

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リンク元	「イオタラム酸」「iothalamate」「iothalamic acid」

「イオタラム酸」

Iotalamic acid
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	V08AA04 (WHO);
Identifiers
	IUPAC name 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid;
PubChem CID	3737;
ChemSpider	3606;
UNII	16CHD79MIX;
KEGG	D01258;
ECHA InfoCard	100.017.181
Chemical and physical data
Formula	C11H9I3N2O4
Molar mass	613.91357
3D model (JSmol)	Interactive image;
	SMILES CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NC)I ;
	InChI InChI=1S/C11H9I3N2O4/c1-3(17)16-9-7(13)4(10(18)15-2)6(12)5(8(9)14)11(19)20/h1-2H3,(H,15,18)(H,16,17)(H,19,20) ; Key:UXIGWFXRQKWHHA-UHFFFAOYSA-N ;