WordNet

a substances that colors metals
stain or tint with a color; "The leaves were tinctured with a bright red"
(pharmacology) a medicine consisting of an extract in an alcohol solution
a nonmetallic element belonging to the halogens; used especially in medicine and photography and in dyes; occurs naturally only in combination in small quantities (as in sea water or rocks) (同)iodin, I, atomic number 53

PrepTutorEJDIC

チンキ(薬をアルコールに溶いたもの) / {U}《しばしばa~》(…)気味,(…な)ところ《+of+名》(trace) / 色;色合い / …‘を'着色する,染める / …‘に'味をつける,風味を与える
ヨード,ヨウ素(非金属元素;化学記号は『I』)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/04/27 00:50:36」(JST)

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Tincture of iodine used to disinfect the area around an epidural catheter.

Tincture of iodine is a disinfectant, it is also called weak iodine solution. Usually 2–7% elemental iodine, along with potassium iodide or sodium iodide, dissolved in a mixture of ethanol and water. As in the case of Lugol's iodine, the role of iodide and water in the solution is to increase the solubility of the elemental iodine, by turning it to the soluble triiodide anion I₃⁻. However, since iodine has moderate solubility in ethanol, it is also assisted by this solvent directly.

Thus, iodine tincture solutions are characterized by the presence of alcohol, and about the same amount (weight % content) of elemental iodine as iodide. Lugol's iodine, by contrast, has no alcohol, and has twice the amount of iodide as elemental iodine.

USP formulas

USP Tincture of Iodine is defined in the U.S. National Formulary (NF) as containing in each 100 mL, 1.8 to 2.2 grams of elemental iodine, and 2.1 to 2.6 grams of sodium iodide. Alcohol is 50 ml and the balance is purified water. This "2% free iodine" solution provides about one mg of free iodine per drop.

USP Strong Iodine Tincture is defined in the NF as containing in each 100 mL, 6.8 to 7.5 gram of iodine, and 4.7 to 5.5 gram of potassium iodide. Purified water is 50 mL and the balance is alcohol. This 7% tincture solution is about 3.5 times more concentrated than USP 2% tincture.

Iodine as disinfectant and nutritional supplement

As both USP solutions contain elemental iodine, which is moderately toxic when ingested in amounts larger than those required to disinfect water, tincture of iodine is sold labeled "for external use only," and used primarily as a disinfectant.

Small amounts may be added to suspect drinking water as a disinfectant (typically 5 mg free iodine per liter, or 5 drops of 2% tincture).

Iodine tincture is not a recommended source of solely-nutritional iodine. Nutritional iodine is better supplied in the form of the less toxic iodide (see SSKI) or iodate salts, which the body can easily convert to thyroid hormone.

Nevertheless, the iodide in tincture of iodine used as a water disinfectant does supply more than adequate nutritional iodine, perhaps 30 or more times the recommended dietary allowance per liter or quart. Application of tincture or Lugol's to the skin also results in absorption and bioavailability of some moderate fraction of the iodine.

Overview

Tincture of iodine is often found in emergency survival kits, used both to disinfect wounds and to sanitize surface water for drinking. When an alcohol solution is not desirable for this purpose, the alcohol-free Lugol's iodine, an aqueous solution of iodine in potassium iodide solution, or else povidone iodine (Betadine), a PVPI solution, can be used.

References

External links

Health Canada Drinking water quality See the section on: water away from home

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English Journal

[Case of iodism complicated with severe airway stenosis due to pharyngolaryngeal edema].

Sorimachi K, Ikegami Y, Suzuki T, Sugeno N, Abe Y, Tsukada Y, Tase C.
Chūdoku kenkyū : Chūdoku Kenkyūkai jun kikanshi = The Japanese journal of toxicology.Chudoku Kenkyu.2013 Dec;26(4):305-9.
A 22-year-old man was admitted to our hospital with dilute iodine tincture poisoning. He had ingested 150 mL in a suicide attempt. On arrival, he was in need of urgent airway management as he was repeatedly vomiting. Although we had difficulty with endotracheal intubation because of remarkable phary
PMID 24483010

Comparative study of disinfectants for use in low-cost gravity driven household water purifiers.

Patil RA1, Kausley SB, Balkunde PL, Malhotra CP.
Journal of water and health.J Water Health.2013 Sep;11(3):443-56. doi: 10.2166/wh.2013.206.
Point-of-use (POU) gravity-driven household water purifiers have been proven to be a simple, low-cost and effective intervention for reducing the impact of waterborne diseases in developing countries. The goal of this study was to compare commonly used water disinfectants for their feasibility of ad
PMID 23981873

Preliminary evaluation of antimicrobial activity of cream formulated with essential oil of Trachyuspermum ammi.

Gilani GR1, Mahmood Z, Hussain M.
Pakistan journal of pharmaceutical sciences.Pak J Pharm Sci.2013 Sep;26(5):893-6.
In our present research we studied physiochemical properties and antimicrobial activity of T. ammi (Trachyuspermum ammi) seeds. The seeds yielded 2.86% essential oil. Refractive index, specific gravity, acid value, and easter values were 1.496, 0.9212, 1.12 and 2.80 respectively. GLC was used to det
PMID 24035943

Japanese Journal

症例報告喉頭浮腫による重篤な上気道狭窄症状を呈したヨウ素中毒の1例

反町光太朗,池上之浩,鈴木剛 [他]
The Japanese journal of clinical toxicology 26(4), 305-309, 2013
NAID 40019903792

和歌山県白浜町で72年ぶりに採取された稀少種アカダマクラゲ(有櫛動物門,カブトクラゲ目,アカダマクラゲ科)

久保田信
日本生物地理学会会報 67, 219-222, 2012-12-20
… No"ink injection"was observed except discharge of solution of iodine tincture after cut of oral lobes in which numerous"ink droplets"were found. …
NAID 120005323866

難治性根尖性歯周炎から分離される微生物に対する各種根管消毒剤の抗菌効果の検討

加藤大輔,小山隆夫,中野雅子,新井高,前田伸子
日本歯科保存学雑誌 53(1), 58-65, 2010-02-28
根管治療は根管の複雑性や治療の困難さから,しばしば失敗することがある.治療成績向上のためには,根管消毒剤の使用が不可欠とされている.しかしながら,根管内に残存する微生物に対するこれらの消毒剤の抗菌性の有効性は確認されていない.そこで,本研究ではin vitro根管モデルを使用して,難治性根尖性歯周炎の歯に残存することが知られている微生物に対する根管消毒剤の抗菌性の有効性を調べた.被験微生物は,En …
NAID 110007880711