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1. 機械的人工換気の肺障害の炎症メカニズム inflammatory mechanisms of lung injury during mechanical ventilation
2. MERSコロナウイルス middle east respiratory syndrome coronavirus

English Journal

Phosphatidylinositol 3-kinases pathway mediates lung caspase-1 activation and high mobility group box 1 production in a toluene-diisocyanate induced murine asthma model.

Liang J1, Zhao H1, Yao L1, Tang H1, Dong H1, Wu Y1, Liu L1, Zou F2, Cai S3.
Toxicology letters.Toxicol Lett.2015 Jul 2;236(1):25-33. doi: 10.1016/j.toxlet.2015.04.011. Epub 2015 Apr 27.
We have previously demonstrated that downregulating HMGB1 decreases airway neutrophil inflammation in a toluene-diisocyanate (TDI)-induced murine asthma model, yet how HMGB1 is regulated in the lung remains uncertain. In this study, we intended to explore whether PI3K signaling pathway mediates pulm
PMID 25929181

Vagotomy reverses established allergen-induced airway hyperreactivity to methacholine in the mouse.

McAlexander MA1, Gavett SH2, Kollarik M3, Undem BJ4.
Respiratory physiology & neurobiology.Respir Physiol Neurobiol.2015 Jul;212-214:20-4. doi: 10.1016/j.resp.2015.03.007. Epub 2015 Apr 1.
We evaluated the role of vagal reflexes in a mouse model of allergen-induced airway hyperreactivity. Mice were actively sensitized to ovalbumin then exposed to the allergen via inhalation. Prior to ovalbumin inhalation, mice also received intratracheally-instilled particulate matter in order to boos
PMID 25842220
PMID 25776760

Tissue distribution of indium after repeated intratracheal instillations of indium-tin oxide into the lungs of hamsters

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Journal of Occupational Health 57(2), 189-192, 2015
… Objectives: The aim of this study was to analyze the tissue distribution of indium after intratracheally instilling indium-tin oxide (ITO) into the lungs of hamsters. …
NAID 130005066083

Tissue distribution of indium after repeated intratracheal instillations of indium-tin oxide into the lungs of hamsters

, , ,
Journal of Occupational Health advpub(0), 2015
… Objectives: The aim of this study was to analyze the tissue distribution of indium after intratracheally instilling indium-tin oxide (ITO) into the lungs of hamsters. …
NAID 130004848079

Efficacy of aerosolized liposomal amphotericin B against murine invasive pulmonary mucormycosis

Mihara Tomo,Kakeya Hiroshi,Izumikawa Koichi,Obata Yoko,Nishino Tomoya,Takazono Takahiro,Kosai Kosuke,Morinaga Yoshitomo,Kurihara Shintaro,Nakamura Shigeki,Imamura Yoshifumi,Miyazaki Taiga,Tsukamoto Misuzu,Yamamoto Yoshihiro,Yanagihara Katsunori,Tashiro Takayoshi,Kohno Shigeru
Journal of Infection and Chemotherapy 20(2), 104-108, 2014-02
… ICR female mice were immunosuppressed with cortisone acetate and cyclophosphamide and challenged on day 0 with 1 × 106 conidia of Rhizopus oryzae (TIMM 1327) intratracheally. …
NAID 120005477014