English Journal

Factors affecting intrasubject variability of PK exposure: absolute oral bioavailability and acidic nature of drugs.

Sato M, Narukawa M.
International journal of clinical pharmacology and therapeutics.Int J Clin Pharmacol Ther.2015 Nov;53(11):955-62. doi: 10.5414/CP202399.
OBJECTIVES: The aim of the present study is to investigate factors affecting intrasubject variability of pharmacokinetic (PK) exposure, which affect the results of bioequivalence (BE) studies. We focused on two factors: absolute oral bioavailability (BA) and acidic nature of drugs.METHODS: Intrasubj
PMID 26365336

Sex-Based Dissociation of White Matter Microstructure in Children With Attention-Deficit/Hyperactivity Disorder.

Jacobson LA1, Peterson DJ2, Rosch KS3, Crocetti D2, Mori S3, Mostofsky SH3.
Journal of the American Academy of Child and Adolescent Psychiatry.J Am Acad Child Adolesc Psychiatry.2015 Nov;54(11):938-46. doi: 10.1016/j.jaac.2015.08.014. Epub 2015 Sep 5.
OBJECTIVE: Sexual dimorphism is evident in attention-deficit/hyperactivity disorder (ADHD), including subtype prevalence, adverse outcomes, and neural phenotype. Neurobiological studies of ADHD suggest that boys show more abnormalities in motor and premotor structure and function, whereas girls diff
PMID 26506584

Fully automatized renal parenchyma volumetry using a support vector machine based recognition system for subject-specific probability map generation in native MR volume data.

Gloger O1, Tönnies K, Mensel B, Völzke H.
Physics in medicine and biology.Phys Med Biol.2015 Oct 28;60(22):8675-8693. [Epub ahead of print]
In epidemiological studies as well as in clinical practice the amount of produced medical image data strongly increased in the last decade. In this context organ segmentation in MR volume data gained increasing attention for medical applications. Especially in large-scale population-based studies or
PMID 26509325

Japanese Journal

Effects of Nutrient Composition of Dinner on Sleep Architecture and Energy Metabolism during Sleep

Intrasubject reproducibility of prefrontal cortex activities during a verbal fluency task over two repeated sessions using multi-channel near-infrared spectroscopy