WordNet
- lying between two extremes in time or space or state; "going from sitting to standing without intermediate pushes with the hands"; "intermediate stages in a process"; "intermediate stops on the route"; "an intermediate range plane"
- a substance formed during a chemical process before the desired product is obtained
- any substance involved in metabolism (either as a product of metabolism or as necessary for metabolism)
PrepTutorEJDIC
- (程度・距離・時間などにおいて)中間の,中間にある(起こる)
- 代謝物質(新陳代謝によって生じる物質)
UpToDate Contents
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- 1. 中等度リスクの子宮体癌に対する補助化学療法 adjuvant treatment of intermediate risk endometrial cancer
- 2. 黒色腫の一次予防 primary prevention of melanoma
- 3. 肥満の病因 pathogenesis of obesity
- 4. バンコマイシン中等度耐性およびバンコマイシン耐性黄色ブドウ球菌感染症 vancomycin intermediate and vancomycin resistant staphylococcus aureus infections
- 5. シャルコーマリートゥース病などの一次性の遺伝性運動感覚性ニューロパチー hereditary primary motor sensory neuropathies including charcot marie tooth disease
English Journal
- Degradation of sulfonamide antibiotics by Microbacterium sp. strain BR1 - elucidating the downstream pathway.
- Ricken B1, Fellmann O1, Kohler HP2, Schäffer A3, Corvini PF4, Kolvenbach BA1.
- New biotechnology.N Biotechnol.2015 Dec 25;32(6):710-5. doi: 10.1016/j.nbt.2015.03.005. Epub 2015 Mar 18.
- Microbacterium sp. strain BR1 is among the first bacterial isolates which were proven to degrade sulfonamide antibiotics. The degradation is initiated by an ipso-substitution, initiating the decay of the molecule into sulfur dioxide, the substrate specific heterocyclic moiety as a stable metabolite
- PMID 25796473
- Cerebrospinal fluid monoamine metabolite concentrations as intermediate phenotypes between glutamate-related genes and psychosis.
- Andreou D1, Söderman E2, Axelsson T3, Sedvall GC2, Terenius L2, Agartz I4, Jönsson EG5.
- Psychiatry research.Psychiatry Res.2015 Sep 30;229(1-2):497-504. doi: 10.1016/j.psychres.2015.06.023. Epub 2015 Jun 27.
- Glutamate-related genes have been associated with schizophrenia, but the results have been ambiguous and difficult to replicate. Homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) are the major degradation products of the monoamines dopamine, sero
- PMID 26142836
- A new cyanogenic metabolite in Arabidopsis required for inducible pathogen defence.
- Rajniak J1, Barco B2, Clay NK2, Sattely ES1.
- Nature.Nature.2015 Sep 17;525(7569):376-9. doi: 10.1038/nature14907. Epub 2015 Sep 9.
- Thousands of putative biosynthetic genes in Arabidopsis thaliana have no known function, which suggests that there are numerous molecules contributing to plant fitness that have not yet been discovered. Prime among these uncharacterized genes are cytochromes P450 upregulated in response to pathogens
- PMID 26352477
Japanese Journal
- A Randomized Study of the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of Clopidogrel in Three Different CYP2C19 Genotype Groups of Healthy Japanese Subjects
- Kobayashi Masahiko,Kajiwara Miyuki,Hasegawa Setsuo
- Journal of Atherosclerosis and Thrombosis advpub(0), 2015
- … Eligible subjects were stratified by dose regimen (300 mg loading dose of clopidogrel on day 1 followed by a 75 mg maintenance dose from days 2 to 7 or a 600 mg loading dose of clopidogrel on day 1 followed by a 150 mg maintenance dose from days 2 to 7) and CYP2C19 metabolizer group [extensive metabolizers (EMs), intermediate metabolizers (IMs), and poor metabolizers (PMs)]. …
- NAID 130005075773
- Carboxylesterase 1-Mediated Drug–Drug Interactions between Clopidogrel and Simvastatin
- Wang Xinwen,Zhu Hao-Jie,Markowitz John Seth
- Biological and Pharmaceutical Bulletin 38(2), 292-297, 2015
- … Our in vitro human liver s9 fraction incubation study demonstrated that simvastatin significantly enhanced the formation of the intermediate metabolite 2-oxo-clopidogrel, and inhibited the CES1-mediated hydrolysis of clopidogrel, 2-oxo-clopidogrel, and the active metabolite. … However, the production of the active metabolite remained unchanged. …
- NAID 130004872259
- Tissue distributions of 4-(hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronide, a stable form of reactive intermediate produced from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, in the rat
- Nishiyama Takahito,Ogura Kenichiro,Ohnuma Tomokazu [他]
- The Journal of toxicological sciences : an official journal of the Japanese Society of Toxicology 39(2), 263-267, 2014-04
- NAID 40020063592
Related Links
- 必应词典为您提供intermediatemetabolite的释义，un. 中间代谢物； 网络释义： 中间代谢产物； ... intermediate metabolite
- Although this intermediate metabolite shares the same molecular weight of 395 with prostamides D 2 and E 2, the product ion spectra of prostamides D 2 and E 2 indicated that there were three consecutive losses of waterm/z ...
Related Pictures
![intermediate metabolite] (GLU: glucuronic](https://1mg.info/0/h/z/2580.jpg)
★リンクテーブル★
| リンク元 | 「中間代謝物」「intermediary metabolite」「intermediate product」 |
| 関連記事 | 「intermediate」「intermedia」 |
「中間代謝物」
「intermediary metabolite」
「intermediate product」
「intermediate」
- n.
- adj.
- 中間の、中間部の、中等の、間性の
- 関
- halfway、intermediary、intermediary body、intermedius、intersex、interstitial、interzonal、middle、moderate
「intermedia」