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Genetic polymorphisms of the renin-angiotensin system and obesity-related metabolic changes in response to low-energy diets in obese women.

Hamada T1, Kotani K, Nagai N, Tsuzaki K, Sano Y, Matsuoka Y, Fujibayashi M, Kiyohara N, Tanaka S, Yoshimura M, Egawa K, Kitagawa Y, Kiso Y, Moritani T, Sakane N.
Nutrition (Burbank, Los Angeles County, Calif.).Nutrition.2011 Jan;27(1):34-9. doi: 10.1016/j.nut.2009.10.012. Epub 2010 Apr 3.
OBJECTIVE: Genetic polymorphisms of the renin-angiotensin system have been implicated in cardiovascular and metabolic diseases. The purpose of this study was to investigate whether the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene and 3123C/A polymorphism of t
PMID 20371166

Yahagi N1, Kosaki R, Ito T, Mitsuhashi T, Shimada H, Tomita M, Takahashi T, Kosaki K.
Congenital anomalies.Congenit Anom (Kyoto).2004 Mar;44(1):18-26.
Hox genes play a critical role in morphogenesis of the early embryo along the anteroposterior axis. In mammals, 39 Hox genes with extensive homology are organized into 13 paralogous groups, forming four clusters on four separate chromosomes. The genes within each cluster are arranged in a 3' to 5' d
PMID 15008896

Duplex and triplex formation of oligodeoxyribonucleotides containing nucleobase-intercalater conjugates.

Kubota M1, Ono A.
Nucleic acids research. Supplement (2001).Nucleic Acids Res Suppl.2002;(2):33-4.
Novel nucleoside analogues constituting of 2'-deoxyinosine and aromatic rings, which are connected by short linker groups, were synthesized and incorporated into oligodeoxyribonucleotides (ODNs). ODNs containing the nucleoside analogues formed stable duplexes and triplexes with target nucleic acids.
PMID 12903091

加賀谷昌美,佐藤安弘,赤上陽一
精密工学会学術講演会講演論文集 2009S(0), 53-54, 2009
本研究では、交流高圧電界印加による微少量液滴の非接触撹拌技術を提案する。振とう器ではμLオーダー液滴の撹拌が進行しにくく、DNAの相補性を発現するハイブリダイゼーションの短時間化が困難である。本報では、この液滴に交流高圧電界を印加することで、活発な溶液挙動を確認し、これを48℃の上記工程に用い、従来方法の1/3の攪拌時間で、インターカレータの発色輝度を高め、これを数値化することで良好な結果を得た。
NAID 130005029719

Homogeneous quantitative assay of hepatitis C virus RNA by polymerase chain reaction in the presence of a fluorescent intercalater

嶋澤るみ子,白井隆一,高橋正人,七田瑞枝,橋本祐一,岩崎成夫
天然有機化合物討論会講演要旨集 (36), 314-321, 1994-09-20
Dynemicin A is a potent antibacterial and antitumor antibiotic having a striking hybrid structure combining the characteristics of both the anthraquinone as a DNA intercalator and diynene as a DNA str …
NAID 110006679306