- 関
- IGFBP-6
WordNet
- want to have; "Id like a beer now!"
- a kind of person; "Well not see his like again"; "I cant tolerate people of his ilk" (同)ilk
- a similar kind; "dogs, foxes, and the like", "we dont want the likes of you around here" (同)the like, the likes of
- equal in amount or value; "like amounts"; "equivalent amounts"; "the same amount"; "gave one six blows and the other a like number"; "the same number" (同)same
- resembling or similar; having the same or some of the same characteristics; often used in combination; "suits of like design"; "a limited circle of like minds"; "members of the cat family have like dispositions"; "as like as two peas in a pod"; "doglike devotion"; "a dreamlike quality" (同)similar
- be fond of; "I like my nephews"
- feel about or towards; consider, evaluate, or regard; "How did you like the Presidents speech last night?"
- find enjoyable or agreeable; "I like jogging"; "She likes to read Russian novels"
- cultivate by growing, often involving improvements by means of agricultural techniques; "The Bordeaux region produces great red wines"; "They produce good ham in Parma"; "We grow wheat here"; "We raise hogs here" (同)raise, farm, produce
- come to have or undergo a change of (physical features and attributes); "He grew a beard"; "The patient developed abdominal pains"; "I got funny spots all over my body"; "Well-developed breasts" (同)develop, produce, get, acquire
- become attached by or as if by the process of growth; "The tree trunks had grown together"
- become larger, greater, or bigger; expand or gain; "The problem grew too large for me"; "Her business grew fast"
- cause to grow or develop; "He grows vegetables in his backyard"
- increase in size by natural process; "Corn doesnt grow here"; "In these forests, mushrooms grow under the trees"; "her hair doesnt grow much anymore"
- (biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level; "he proposed an indicator of osseous development in children" (同)growing, maturation, development, ontogeny, ontogenesis
- (pathology) an abnormal proliferation of tissue (as in a tumor)
- a progression from simpler to more complex forms; "the growth of culture"
- something grown or growing; "a growth of hair"
- vegetation that has grown; "a growth of trees"; "the only growth was some salt grass"
- be a contributing factor; "make things factor into a companys profitability"
- any of the numbers (or symbols) that form a product when multiplied together
- an independent variable in statistics
- anything that contributes causally to a result; "a number of factors determined the outcome"
- consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
- resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
- executed with proper legal authority; "a binding contract"
- the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
- strip sewn over or along an edge for reinforcement or decoration
- the capacity to attract and hold something
PrepTutorEJDIC
- …‘を'『好む』,‘が'好きである / 《しばしば否定文で,またwould,《英》shouldと共に用いて》…‘を'望む,…したい / 『好む』;望む / 《複数形で》好み,好きな事
- (外観・性質などが)…『に似た』,のような / (やり方,程度などが)…『と同じように』 / …『らしい』,にふさわいし / 《おもに話》たとえば…のような / 《名詞の前にのみ用いて》(性質・外観などが)同じの,(数量が)等しい / 《補語にのみ用いて》似ている,そっくりで / たぶん,おそらく(probably) / (…に)似た人(物),(…と)同等の人(物),匹敵する人(物)《+『of』+『名』》 / …のように / あたかも…のように
- 『成長する』,育つ,〈植物が〉生える,茂る / (類・量・程などにおいて)『増大する』,大きくなる / 『しだいになる』 / …‘を'成長させる,大きくする,育てる / …から生じる(起こる)
- 〈U〉(…の)『成長』,発育;『発達』,発展《+『of』+『名』》 / 〈U〉(数・量,重要性・力などの)『増加』,増大,拡張《+『of』+『名』》 / 〈U〉《修飾語[句]を伴って》栽培,生産,…産 / 〈C〉成育した物,(草,木,髪,ひげなどの)生えたもの / 〈C〉腫瘍(しゅよう)
- (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
- 義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
UpToDate Contents
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English Journal
- Insulin-like growth factor-binding protein-6 and cancer.
- Bach LA, Fu P, Yang Z.SourceDepartment of Medicine, Monash University, Melbourne, Australia. leon.bach@monash.edu
- Clinical science (London, England : 1979).Clin Sci (Lond).2013 Feb;124(4):215-29. doi: 10.1042/CS20120343.
- The IGF (insulin-like growth factor) system is essential for physiological growth and it is also implicated in a number of diseases including cancer. IGF activity is modulated by a family of high-affinity IGF-binding proteins, and IGFBP-6 is distinctive because of its marked binding preference for I
- PMID 23126425
- Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations.
- Galimberti F, Busch AM, Chinyengetere F, Ma T, Sekula D, Memoli VA, Dragnev KH, Liu F, Johnson KC, Guo Y, Freemantle SJ, Andrew AS, Greninger P, Robbins DJ, Settleman J, Benes C, Dmitrovsky E.SourceDepartment of Pharmacology and Toxicology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
- International journal of oncology.Int J Oncol.2012 Nov;41(5):1751-61. doi: 10.3892/ijo.2012.1599. Epub 2012 Aug 22.
- Hedgehog (HH) pathway Smoothened (Smo) inhibitors are active against Gorlin syndrome-associated basal cell carcinoma (BCC) and medulloblastoma where Patched (Ptch) mutations occur. We interrogated 705 epithelial cancer cell lines for growth response to the Smo inh
- PMID 22923130
- Evolution of the urinary proteome during human renal development and maturation: variations with gestational and postnatal age.
- Charlton JR, Norwood VF, Kiley SC, Gurka MJ, Chevalier RL.SourceDepartment of Pediatrics, University of Virginia, Charlottesville, USA. jrc6n@virginia.edu
- Pediatric research.Pediatr Res.2012 Aug;72(2):179-85.
- BACKGROUND: Low birth weight is associated with deficits in nephron number in the infant kidney and increased risk of adulthood hypertension and renal dysfunction. Urinary biomarkers may be potential indicators of renal reserve, but little is known about the influence of gestational and postnatal ag
- PMID 22580717
Japanese Journal
- Responses of insulin-like growth factor (IGF)-I and two IGF-binding protein-1 subtypes to fasting and re-feeding, and their relationships with individual growth rates in yearling masu salmon (Oncorhynchus masou)
- Kawaguchi Kohei,Kaneko Nobuto,Fukuda Miki,Nakano Yusuke,Kimura Shizuo,Hara Akihiko,Shimizu Munetaka
- Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 165(2), 191-198, 2013-06-00
- … Two subtypes of insulin-like growth factor binding protein (IGFBP)-1 are present in salmon blood and they are both up-regulated under catabolic conditions such as stress. … The present study examined effects of fasting and re-feeding on IGFBP-1a (28-kDa form) and IGFBP-1b (22-kDa form) both at mRNA and protein levels along with IGF-I and RNA/DNA ratio in yearling masu salmon. …
- NAID 120005228716
- 乳がん細胞株におけるビタミンB_6の遺伝子発現調節作用
- 叶内 宏明,岡 達三
- ビタミン 86(8), 425-431, 2012-08-25
- … Five mM pyridoxine or 0.5 mM pyridoxal (PL) completely inhibited MCF-7 cell growth. … cAMP response element binding protein (CREB) regulates annexin A1 gene expression. … B_6 inhibited the action of CREB as a transcription factor. …
- NAID 110009489785
- Influence of catch-up growth on IGFBP-2 levels and association between IGFBP-2 and cardiovascular risk factors in Korean children born SGA
- KO Jung Min,PARK Hong Kyu,YANG Seung,HWANG Il Tae
- Endocrine journal 59(8), 725-733, 2012-08-01
- NAID 10031064793
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Related Pictures
★リンクテーブル★
[★]
- 関
- insulin-like growth factor binding protein 6
[★]
- 英
- insulin-like growth factor binding protein 6、IGFBP-6
- 関
- インスリン様成長因子結合タンパク質6
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- 英
- insulin-like growth factor binding protein 6、IGFBP-6
- 関
- インスリン様増殖因子結合タンパク質6
[★]
- 関
- affinity、associate、bind、bond、bonding、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、connective、connectivity、couple、dock、engage、engagement、join、ligate、linkage、symphysial、symphysic、union
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- 関
- alike、as well as、care for、correspond、correspondingly、equally、favor、identically、likewise、prefer、resemble、same、similar、similarly、such
[★]
- (過去: grew-過去分詞: grown)
- 関
- extend、growth、outgrow、outgrowth、stretch
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- 関
- actual、actually、in fact、in practice、indeed、practically
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- 関
- element、elementary、factorial、parameter