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English Journal
- Crystal Structure of the Human tRNA m1A58 Methyltransferase-tRNA3Lys Complex: Refolding of Substrate tRNA allows Access to the Methylation Target.
- Finer-Moore J1, Czudnochowski N2, O'Connell JD 3rd2, Wang AL2, Stroud RM2.
- Journal of molecular biology.J Mol Biol.2015 Oct 12. pii: S0022-2836(15)00565-3. doi: 10.1016/j.jmb.2015.10.005. [Epub ahead of print]
- Human tRNA3Lys is the primer for reverse transcription of HIV; the 3' end is complementary to the primer-binding site on HIV RNA. The complementarity ends at the 18th base, A58, which in tRNA3Lys is modified to remove Watson-Crick pairing. Motivated to test the role of the modification in terminatin
- PMID 26470919
- Structure of mammalian eIF3 in the context of the 43S preinitiation complex.
- des Georges A1, Dhote V2, Kuhn L3, Hellen CU2, Pestova TV2, Frank J1,4, Hashem Y5.
- Nature.Nature.2015 Sep 24;525(7570):491-5. doi: 10.1038/nature14891. Epub 2015 Sep 7.
- During eukaryotic translation initiation, 43S complexes, comprising a 40S ribosomal subunit, initiator transfer RNA and initiation factors (eIF) 2, 3, 1 and 1A, attach to the 5'-terminal region of messenger RNA and scan along it to the initiation codon. Scanning on structured mRNAs also requires the
- PMID 26344199
- Roles of helix H69 of 23S rRNA in translation initiation.
- Liu Q1, Fredrick K2.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2015 Sep 15;112(37):11559-64. doi: 10.1073/pnas.1507703112. Epub 2015 Aug 31.
- Initiation of translation involves the assembly of a ribosome complex with initiator tRNA bound to the peptidyl site and paired to the start codon of the mRNA. In bacteria, this process is kinetically controlled by three initiation factors-IF1, IF2, and IF3. Here, we show that deletion of helix H69
- PMID 26324939
Japanese Journal
- 三好 祐一,渡邉 和則
- 日本ハイパーサーミア学会誌 34(3), 23-34, 2018
- … はnSBsに注目する.<br>nSBsは1989年に発見され,その後多くのnSBs構成タンパク質及びRNAが同定されている.nSBsの主な構成因子はHeat shock transcription factorファミリーやスプライシング因子,Satellite III RNAや開始tRNAなどの非コードRNAである.近年,多くの研究者がnSBs形成機構を報告している一方で,nSBsの細胞内機構は未だ明らかになっていない.本総説では,nSBsの形成機構やnSBs構成因子の細胞内機能などの基礎研究につ …
- NAID 130007520470
- Granule formation of elongator-specific methionine transfer RNA caused by X-ray irradiation in a non-small lung carcinoma cell line (NCI-H1299)
- Katano Atsuto,Nakagawa Keiichi,Miyagawa Ryu,Kobayashi Reiko,Yamashita Hideomi,Morikawa Teppei,Sakumi Akira,Tamari Yuki,Fukayama Masashi,Ohtomo Kuni
- bioimages 25(0), 1-6, 2017
- … We herein report the subcellular distribution of methionine transfer RNA (tRNA<SUP>Met</SUP>), which has two forms of initiator tRNA<SUP>Met</SUP> … (Meti) and elongator tRNA<SUP>Met</SUP> … A recent report showed that the formation of tRNA<SUP>Met</SUP> … We analyzed the subcellular distribution change in tRNA<SUP>Met</SUP> …
- NAID 130006073223
- Incorporation of Fluorescent-Labeled Non-.ALPHA.-Amino Carboxylic Acids into the N-Terminus of Proteins in Response to Amber Initiation Codon
- Miura Masanori,Muranaka Norihito,Abe Ryoji,Hohsaka Takahiro
- Bulletin of the Chemical Society of Japan 83(5), 546-553, 2010
- … A series of TAMRA-labeled amino carboxylic acids were synthesized and attached to an amber suppressor initiator tRNA derived from <i>Escherichia coli</i> … initiator tRNA. … Fluorescent-labeled amino carboxylic acids were successfully incorporated into the N-terminus of streptavidin by adding TAMRA-acylated initiator tRNAs to an <i>E. …
- NAID 130004152733
Related Links
- The initiator tRNA must serve functions distinct from those of other tRNAs, evading binding to elongation factors and instead binding directly to the ribosomal P site with the aid of initiation factors. It also plays a key role ...
- one of two tRNA binding sites on a ribosome that holds the incoming tRNA molecule charged with an amino acid. Called also A site. ... one of two tRNA binding sites on a ribosome that holds the tRNA that is normally linked to the ...
- Initiator-tRNA w, Starter-tRNA, die N-Formyl-Methionyl-tRNA bei der bakteriellen bzw. die Methionyl-tRNA bei der eukaryotischen Translation. ... Falls Sie schon Kunde bei uns sind, melden Sie sich bitte hier mit Ihrer E-Mail-Adresse ...
Related Pictures
★リンクテーブル★
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- 関
- initiator tRNA、tRNAMet
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- 英
- initiator tRNA
- 関
- メチオニン転移RNA
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トランスファーRNA, transfer RNA, 転位RNA
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トランスファーRNA transfer RNAs
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