infernal

WordNet

of or pertaining to or characteristic of a very uncontrolled and intense fire; "infernal heat"
an inhabitant of Hell; "his roar made the infernals quake"
being of the underworld; "infernal regions"
characteristic of or resembling Hell; "infernal noise"; "infernal punishment"
extremely; "infernally clever"; "hellishly dangerous" (同)hellishly

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地獄の / 悪魔のような,極悪非道な / 《名詞の前にのみ用いて》《古話》ひどい,たまらない

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/04/27 06:12:20」(JST)

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English Journal

LocARNAscan: Incorporating thermodynamic stability in sequence and structure-based RNA homology search.

Will S, Siebauer MF, Heyne S, Engelhardt J, Stadler PF, Reiche K, Backofen R.AbstractBACKGROUND: The search for distant homologs has become an import issue in genome annotation. A particular difficulty is posed by divergent homologs that have lost recognizable sequence similarity. This same problem also arises in the recognition of novel members of large classes of RNAs such as snoRNAsor microRNAs that consist of families unrelated by common descent. Current homology search tools for structured RNAs are either based entirely on sequence similarity (such as blast or hmmer) or combine sequence and secondary structure. The most prominent example of the latter class of tools is Infernal. Alternatives are descriptor-based methods. In most practical applications published to-date, however, the information contained in covariance models or manually prescribed search patterns is dominated by sequence information. Here we ask two related questions: (1) Is secondary structure alone informative for homology search and the detection of novel members of RNA classes? (2) To what extent is the thermodynamic propensity of the target sequence to fold into the correct secondary structure helpful for this task?
Algorithms for molecular biology : AMB.Algorithms Mol Biol.2013 Apr 20;8(1):14. [Epub ahead of print]
BACKGROUND: The search for distant homologs has become an import issue in genome annotation. A particular difficulty is posed by divergent homologs that have lost recognizable sequence similarity. This same problem also arises in the recognition of novel members of large classes of RNAs such as snoR
PMID 23601347

RNA structures regulating ribosomal protein biosynthesis in bacilli.

Deiorio-Haggar K, Anthony J, Meyer MM.SourceBoston College Department of Biology; Chestnut Hill, MA USA.
RNA biology.RNA Biol.2013 Apr 11;10(7). [Epub ahead of print]
In Bacilli, there are three experimentally validated ribosomal-protein autogenous regulatory RNAs that are not shared with E. coli. Each of these RNAs forms a unique secondary structure that interacts with a ribosomal protein encoded by a downstream gene, namely S4, S15 and L20. Only one of these RN
PMID 23611891

An Infernal Trio: The chemokine CXCL12 and its receptors CXCR4 and CXCR7 in tumor biology.

Hattermann K, Mentlein R.SourceDepartment of Anatomy, University of Kiel, Olshausenstr. 40, 24098 Kiel, Germany. Electronic address: k.hattermann@anat.uni-kiel.de.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft.Ann Anat.2013 Mar;195(2):103-10. doi: 10.1016/j.aanat.2012.10.013. Epub 2012 Dec 8.
Chemokines are small peptide mediators that play a role in many physiological and pathological processes. Apart from their initially discovered function in trafficking of leukocytes, they also influence migration, proliferation, survival and gene expression of a variety of cell types in their respec
PMID 23279723

Efficient known ncRNA search including pseudoknots.

Yuan C, Sun Y.SourceDepartment of Computer Science and Engineering, Michigan State University, East Lansing, MI 48824, USA. yannisun@msu.edu
BMC bioinformatics.BMC Bioinformatics.2013;14 Suppl 2:S25. doi: 10.1186/1471-2105-14-S2-S25. Epub 2013 Jan 21.
BACKGROUND: Searching for members of characterized ncRNA families containing pseudoknots is an important component of genome-scale ncRNA annotation. However, the state-of-the-art known ncRNA search is based on context-free grammar (CFG), which cannot effectively model pseudoknots. Thus, existing CFG
PMID 23369049

Japanese Journal

Asymmetry of the Variability of Heart Rate and Conduction Time Between Atria and Ventricles

Circulation journal : official journal of the Japanese Circulation Society 77(12), 2904-2911, 2013-11-25
NAID 10031203574

Mantle cell lymphoma に対する連続的自家末梢血幹細胞移植併用大量化学療法の臨床的検討

臨床血液 51(1), 57-62, 2010-01-30
NAID 10026332098

国境線上のカウボーイ--コーマック・マッカーシー『すべての美しい馬』試論

言語情報科学 (8), 183-199, 2010
NAID 40017096017

『地獄の季節』「錯乱1」考察--「狂気の処女」による性の越境

言語と文化 (21), 140-156, 2008
NAID 40016650422

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