- 関
- immune surveillance、immunologic surveillance、immunological surveillance
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/27 22:41:36」(JST)
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Cancer immunosurveillance is a process by which an organism's immune system recognizes transformed cells in order to inhibit the growth of neoplastic tissue.[1] It comprises the first phase of immunoediting and is also known as the elimination phase.[2]
See also
References
- ^ Slaney, C. Y.; Rautela, J.; Parker, B. S. (23 September 2013). "The Emerging Role of Immunosurveillance in Dictating Metastatic Spread in Breast Cancer". Cancer Research 73 (19): 5852–5857. doi:10.1158/0008-5472.CAN-13-1642.
- ^ Dunn, Gavin P.; Old, Lloyd J.; Schreiber, Robert D. (August 2004). "The Immunobiology of Cancer Immunosurveillance and Immunoediting". Immunity 21 (2): 137–148. doi:10.1016/j.immuni.2004.07.017. PMID 15308095.
UpToDate Contents
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- 1. IgE単独欠損の臨床的意義clinical significance of isolated ige deficiency [show details]
…properties in vitro and in experimental mice . IgE has been shown to play an active role in tumor immunosurveillance in mice and to induce human colon cancer cell apoptosis in vitro by enhancing cyp27b1 expression…
- 2. びまん性大細胞型B細胞性リンパ腫および原発性縦隔大細胞型B細胞リンパ腫の病理学pathobiology of diffuse large b cell lymphoma and primary mediastinal large b cell lymphoma [show details]
…Approximately 60 percent of DLBCL cases fail to express class I MHC complexes that are needed for immunosurveillance by cytotoxic T cells. Mechanisms include loss-of-function mutations in beta-2 microglobulin …
- 3. ウィスコット・オルドリック症候群wiskott aldrich syndrome [show details]
…cells are thought to play an important role in protection against autoimmunity and in cancer immunosurveillance. These iNKT cells are completely absent in patients with WAS and reduced in patients with X-linked…
English Journal
- Endogenous antibody responses to mucin 1 in a large multiethnic cohort of patients with breast cancer and healthy controls: Role of immunoglobulin and Fcγ receptor genes.
- Pandey JP1, Namboodiri AM2, Wolf B3, Iwasaki M4, Kasuga Y5, Hamada GS6, Tsugane S7.
- Immunobiology.Immunobiology.2018 Feb;223(2):178-182. doi: 10.1016/j.imbio.2017.10.028. Epub 2017 Oct 18.
- PMID 29074302
- Cancer-derived extracellular vesicles: friend and foe of tumour immunosurveillance.
- Dörsam B1, Reiners KS2, von Strandmann EP3.
- Philosophical transactions of the Royal Society of London. Series B, Biological sciences.Philos Trans R Soc Lond B Biol Sci.2018 Jan 5;373(1737). pii: 20160481. doi: 10.1098/rstb.2016.0481.
- PMID 29158311
- Survival of the fittest: Cancer challenges T cell metabolism.
- Franchina DG1, He F2, Brenner D3.
- Cancer letters.Cancer Lett.2018 Jan 1;412:216-223. doi: 10.1016/j.canlet.2017.10.014. Epub 2017 Oct 24.
- PMID 29074426
Japanese Journal
- がんの免疫監視,免疫編集,そして治療へ (第1土曜特集 がん免疫療法の躍進) -- (がん免疫療法の基礎から臨床へ)
- アレルギー,IgE発見50周年,IgEの生物学的意義について
- 臨床免疫・アレルギー科 = Clinical immunology & allergology 67(2), 181-187, 2017-02
- NAID 40021094190
- Intravital Förster resonance energy transfer imaging reveals osteopontin-mediated polymorphonuclear leukocyte activation by tumor cell emboli
Related Links
- がん細胞は、「免疫監視機構から逃れる能力」という特性を獲得すると考えられています。がん細胞が免疫監視機構による認識・排除から逃れることが、腫瘍の増殖・進行につながります。
- 1950年代、異物(非自己)を排除する免疫系は、自己の変異細胞であるがん細胞も排除して生体を防御するという「がん免疫監視説(cancer immunosurveillance)」の概念が提唱されました 1)。 しかし、がん免疫監視機構が存在するにも ...
- Cancer immunosurveillance in humans If indeed cancer immunosurveillance exists in mice, does it exist in humans? The logical prediction from the immunosurveillance hypothesis is that immunodeficient or ...
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- 英
- immune surveillance、immunosurveillance、immunological surveillance、immunologic surveillance
- 関
- 免疫監視機構
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- 関
- immune surveillance、immunological surveillance、immunosurveillance