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1. 重症筋無力症に対する長期免疫療法 chronic immunomodulating therapies for myasthenia gravis
2. 重症筋無力症の治療 treatment of myasthenia gravis
3. 筋無力症クリーゼ myasthenic crisis
4. ヒトヘルペスウイルス8感染のウイルス学、疫学、および伝播 virology epidemiology and transmission of human herpesvirus 8 infection
5. 腎移植後に起こる感染症の鑑別診断 differential diagnosis of infection following renal transplantation

English Journal

Sulfated modification of the polysaccharides from Ganoderma atrum and their antioxidant and immunomodulating activities.

Chen Y1, Zhang H1, Wang Y1, Nie S1, Li C1, Xie M2.
Food chemistry.Food Chem.2015 Nov 1;186:231-8. doi: 10.1016/j.foodchem.2014.10.032. Epub 2014 Nov 7.
In this study, three chemically sulfated polysaccharides (S-PSG) with different degree of sulfate substitution (DS) were derived from Ganoderma atrum. FT-IR and (13)C NMR spectra indicated that the substitution was predominantly on C-6 position compared with the C-2 position. The antioxidant and imm
PMID 25976815

Integrated analysis of toxicity data of two pharmaceutical immunosuppressants and two environmental pollutants with immunomodulating properties to improve the understanding of side effects-A toxicopathologist׳s view.

Kuper CF1, Vogels J2, Kemmerling J3, Fehlert E4, Rühl-Fehlert C5, Vohr HW3, Krul C2.
European journal of pharmacology.Eur J Pharmacol.2015 Jul 15;759:343-55. doi: 10.1016/j.ejphar.2015.03.045. Epub 2015 Mar 28.
Data in a toxicity test are evaluated generally per parameter. Information on the response per animal in addition to per parameter can improve the evaluation of the results. The results from the six studies in rats, described in the paper by Kemmerling, J., Fehlert, E., Rühl-Fehlert, C., Kuper, C.F
PMID 25824899

The transferability from rat subacute 4-week oral toxicity study to translational research exemplified by two pharmaceutical immunosuppressants and two environmental pollutants with immunomodulating properties.

Kemmerling J1, Fehlert E2, Kuper CF3, Rühl-Fehlert C4, Stropp G5, Vogels J3, Krul C3, Vohr HW6.
European journal of pharmacology.Eur J Pharmacol.2015 Jul 15;759:326-42. doi: 10.1016/j.ejphar.2015.03.032. Epub 2015 Mar 28.
Exposure to chemicals may have an influence on the immune system. Often, this is an unwanted effect but in some pharmaceuticals, it is the intended mechanism of action. Immune function tests and in depth histopathological investigations of immune organs were integrated in rodent toxicity studies per
PMID 25823813

Reactivation of hepatitis viruses following immunomodulating systemic chemotherapy

WATANABE Tsunamasa,TANAKA Yasuhito
Hepatology research : the official journal of the Japan Society of Hepatology 43(2), 113-121, 2013-02-01
NAID 10031194530