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Immunogenic inhibition of prominent ruminal bacteria as a means to reduce lipolysis and biohydrogenation activity in vitro.

Edwards HD1, Shelver WL2, Choi S3, Nisbet DJ4, Krueger NA4, Anderson RC4, Smith SB5.
Food chemistry.Food Chem.2017 Mar 1;218:372-377. doi: 10.1016/j.foodchem.2016.09.052. Epub 2016 Sep 8.
Lipolysis and biohydrogenation in ruminal animals promote the accumulation of saturated fatty acids in their meat and milk. Antibodies were generated against key ruminal lipase contributors Anaerovibrio lipolyticus, Butyrivibrio fibrisolvens, Propionibacterium avidum and acnes. An anti-Pseudomonas l
PMID 27719923

Particulate beta-glucan induces early and late phagosomal maturation in murine macrophages.

Fatima N1, Upadhyay T1, Sharma D2, Sharma R3.
Frontiers in bioscience (Elite edition).Front Biosci (Elite Ed).2017 Jan 1;9:129-140.
Beta-glucans are carbohydrates (glucose polymers) found in the cell walls of fungi, yeast, algae, lichens, and plants such as oats and barley. Beta-glucans bind to glucan receptor on phagocytic cells and modify these cells to become "immunologically active" by generating a variety of innate immune r
PMID 27814595

E3 ubiquitin ligase NKLAM ubiquitinates STAT1 and positively regulates STAT1-mediated transcriptional activity.

Lawrence DW1, Kornbluth J2.
Cellular signalling.Cell Signal.2016 Dec;28(12):1833-1841. doi: 10.1016/j.cellsig.2016.08.014. Epub 2016 Aug 26.
Signal transducer and activator of transcription 1 (STAT1) is critically important for the transcription of a large number of immunologically relevant genes. In macrophages, interferon gamma (IFNγ) signal transduction occurs via the JAK/STAT pathway and ends with the transcription of a number of ge
PMID 27570112