WordNet

a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response (同)Ig, immune serum globulin, immune gamma globulin, immune_globulin

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Leung Y1, Panaccione R2.
Gastroenterology clinics of North America.Gastroenterol Clin North Am.2014 Sep;43(3):619-630. doi: 10.1016/j.gtc.2014.05.013.
Despite the success of antitumor necrosis factor (TNF) therapy in Crohn's disease, there remains a need for biologic therapy that targets other immune pathways of disease. Ustekinumab is a fully human monoclonal immunoglobulin antibody that targets the interleukin (IL)-12 and IL-23 shared P40 subuni
PMID 25110262

Prevalence of anti-N-methyl-d-aspartate (NMDA) receptor antibodies in patients with schizophrenia and related psychoses: a systematic review and meta-analysis.

Pollak TA1, McCormack R1, Peakman M2, Nicholson TR3, David AS3.
Psychological medicine.Psychol Med.2014 Sep;44(12):2475-87. doi: 10.1017/S003329171300295X. Epub 2013 Dec 13.
BACKGROUND: Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is an autoimmune condition caused by immunoglobulin (Ig)G antibodies directed against the NR1 subunit of the NMDA glutamate receptor. Approximately 65% of cases present with psychiatric symptoms, particularly psychosis. It remains to
PMID 24330811

A novel antigen-carrier system: The Mycobacterium tuberculosis Acr protein carried by raw starch microparticles.

Moreno-Mendieta SA1, Guillén D2, Espitia C3, Hernández-Pando R4, Sanchez S3, Rodríguez-Sanoja R5.
International journal of pharmaceutics.Int J Pharm.2014 Aug 2. pii: S0378-5173(14)00540-7. doi: 10.1016/j.ijpharm.2014.07.041. [Epub ahead of print]
Microparticles have been used as promising carriers for in vivo vaccine delivery. However, the processes for immobilizing peptides or proteins on microparticles usually require the use of undesirable compounds and complex protocols. In this work, we propose a new immobilization and delivery system w
PMID 25093695

Expression of N-Methyl-D-Aspartate Receptor Subunits in the Bovine Ovum: Ova as a Potential Source of Autoantigens Causing Anti-NMDAR Encephalitis

Tachibana Naoko,Kinoshita Michiaki,Kametani Fuyuki,Tanaka Keiko,Une Yumi,Komatsu Yotaro,Kobayashi Yukihiro,Ikeda Shu-ichi
The Tohoku Journal of Experimental Medicine 235(3), 223-231, 2015
… It is associated with antibodies against the extracellular region of the NR1 subunit of postsynaptic NMDAR. … Immunocytochemical analysis revealed that the bovine ovum was stained with the immunoglobulin G purified from the serum of a patient with anti-NMDAR encephalitis. …
NAID 130004822446

Stable Expression and Characterization of Monomeric and Dimeric Recombinant Hybrid-IgG/IgA Immunoglobulins Specific for Shiga Toxin

Iwata Koki,Kurohane Kohta,Nakanishi Katsuhiro,Miyake Masaki,Imai Yasuyuki
Biological and Pharmaceutical Bulletin 37(9), 1510-1515, 2014
… Antigen-specific immunoglobulin A (IgA) may be useful for preventing infectious diseases through passive immunization on the mucosal surface. … We previously established mouse IgA and IgG monoclonal antibodies (mAbs) specific for the binding subunit of Shiga toxin 1 (Stx1B). …
NAID 130004147362

Grúz Petr,Nohmi Takehiko
Genes and Environment 35(1), 10-20, 2013
… However, hPolη is also a very low fidelity enzyme when copying undamaged DNA or DNA with other adducts and is actively recruited during the somatic hypermutation of the immunoglobulin genes. … The catalytic core lacking the C-terminal part of hPolη was even more biologically active than the full size protein and its activity was further enhanced by attaching the prokaryotic β-subunit binding motif to it. …
NAID 130004481201