English Journal

Regulation of the hyperosmotic induction of aquaporin 5 and VEGF in retinal pigment epithelial cells: involvement of NFAT5.

Hollborn M1, Vogler S2, Reichenbach A2, Wiedemann P1, Bringmann A1, Kohen L3.
Molecular vision.Mol Vis.2015 Apr 9;21:360-77. eCollection 2015.
PURPOSE: High intake of dietary salt increases extracellular osmolarity, which results in hypertension, a risk factor of neovascular age-related macular degeneration. Neovascular retinal diseases are associated with edema. Various factors and channels, including vascular endothelial growth factor (V
PMID 25878490

Shen B1, Wong CO2, Lau OC2, Woo T2, Bai S3, Huang Y2, Yao X2.
PloS one.PLoS One.2015 Apr 7;10(4):e0122227. doi: 10.1371/journal.pone.0122227. eCollection 2015.
Mechanical forces exerted on cells impose stress on the plasma membrane. Cells sense this stress and elicit a mechanoelectric transduction cascade that initiates compensatory mechanisms. Mechanosensitive ion channels in the plasma membrane are responsible for transducing the mechanical signals to el
PMID 25849346

TRPV4 channels activity in bovine articular chondrocytes: regulation by obesity-associated mediators.

Sánchez JC1, López-Zapata DF2, Wilkins RJ3.
Cell calcium.Cell Calcium.2014 Dec;56(6):493-503. doi: 10.1016/j.ceca.2014.10.006. Epub 2014 Oct 25.
Turnover of the cartilage extracellular matrix depends exclusively on chondrocytes and varies in response to load and osmolarity fluctuations. Obesity can affect chondrocyte physiology; adipokines, insulin and proinflammatory cytokines levels are all altered in the obese and are related to matrix tu
PMID 25459300

Japanese Journal

A Novel Subgroup of bZIP Proteins Functions as Transcriptional Activators in Hypoosmolarity-Responsive Expression of the ProDH Gene in Arabidopsis

ACTCAT, a novel cis-acting element for proline- and hypoosmolarity-responsive expression of the ProDH gene encoding proline dehydrogenase in Arabidopsis