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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/09/18 16:23:53」(JST)
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In biology, "polyphagia" is a type of phagy, referring to an animal that feeds on many kinds of food.
Polyphagia
ICD-10 |
R63.2 |
ICD-9 |
783.6 |
Polyphagia or hyperphagia refers to excessive hunger or increased appetite.[1] It derives from the Greek words πολύς (polys) which means "very much", and φαγῶ (phago) meaning "eat".
Contents
- 1 In medicine
- 2 Causes
- 2.1 Diabetic ketoacidosis
- 3 See also
- 4 References
- 5 External links
In medicine[edit source | edit]
In medicine, polyphagia (sometimes known as hyperphagia) is a medical sign meaning excessive hunger and abnormally large intake of solids by mouth. Disorders such as diabetes, Kleine-Levin Syndrome (a malfunction in the hypothalamus), the genetic disorders Prader-Willi Syndrome and Bardet Biedl Syndrome can cause hyperphagia (compulsive hunger).[2]
Causes[edit source | edit]
Causes of increased appetite include:[3]
- Anxiety
- Certain drugs
- Diabetes mellitus
- Hyperthyroidism
- Hypoglycemia
- Premenstrual syndrome
- Prader-Willi syndrome
- Bulimia
- Graves' disease
Diabetic ketoacidosis[edit source | edit]
Polyphagia usually occurs early in the course of diabetic ketoacidosis.[4] However, once insulin deficiency becomes more severe and ketoacidosis develops, appetite is suppressed.[5]
See also[edit source | edit]
- Hunger
- Overeating
- Compulsive overeating
- Binge eating
- Binge eating disorder
- Eating disorder
- Polydipsia
- Anorexia
- Diabetes mellitus
- Charles Domery
- Tarrare
- Effects of cannabis
- Erysichthon of Thessaly
References[edit source | edit]
- ^ Berthoud HR, Lenard NR, Shin AC (2011). "Food reward, hyperphagia, and obesity.". Am J Physiol Regul Integr Comp Physiol 300 (6): R1266–77. doi:10.1152/ajpregu.00028.2011. PMC 3119156. PMID 21411768.
- ^ OMIM::Prader-WilliOMIM::Bardet-Biedl
- ^ NIH Medline plus
- ^ Elliott RE, Jane JA, Wisoff JH (2011). "Surgical management of craniopharyngiomas in children: meta-analysis and comparison of transcranial and transsphenoidal approaches.". Neurosurgery 69 (3): 630–43; discussion 643. doi:10.1227/NEU.0b013e31821a872d. PMID 21499159.
- ^ Masuzaki H, Tanaka T, Ebihara K, Hosoda K, Nakao K (2009). "Hypothalamic melanocortin signaling and leptin resistance--perspective of therapeutic application for obesity-diabetes syndrome.". Peptides 30 (7): 1383–6. doi:10.1016/j.peptides.2009.04.008. PMID 19394382.
External links[edit source | edit]
- Diseases and conditions associated with Polyphagia
Symptoms and signs: Symptoms concerning nutrition, metabolism and development (R62–R64, 783)
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Ingestion/Weight |
decrease: Anorexia • Weight loss/Cachexia/Underweight
increase: Polyphagia • Polydipsia • Orexigenia • Weight gain
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Growth |
Delayed milestone • Failure to thrive • Short stature (e.g., Idiopathic)
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noco (d)/cong/tumr, sysi/epon
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proc, drug (A10/H1/H2/H3/H5)
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noco, nuvi, sysi/epon, met
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UpToDate Contents
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English Journal
- Alpha(1) receptor antagonist in the median raphe nucleus evoked hyperphagia in free-feeding rats.
- Mansur SS, Terenzi MG, Neto JM, Faria MS, Paschoalini MA.SourceDepartment of Physiological Sciences, Centre of Biological Sciences - CCB, Federal University of Santa Catarina (UFSC), 88040-970, Florianopolis, SC, Brazil.
- Appetite.Appetite.2011 Oct;57(2):498-503. Epub 2011 Jul 2.
- Serotonergic neurons in the median raphe nucleus (MnR) are stimulated by α(1)-adrenergic agonists and inhibited by α(2)-agonists. This study investigated the effect of the blockade of the MnR α(1)-adrenergic receptors of free feeding rats as an attempt to elucidate the functional role of these re
- PMID 21745511
- Seasonal Regulation of the Growth Hormone/Insulin-like Growth Factor-I Axis in the American Black Bear (Ursus americanus).
- Blumenthal S, Morgan-Boyd R, Nelson R, Garshelis DL, Turyk ME, Unterman T.Source1UIC College of Medicine and Jesse Brown VAMC.
- American journal of physiology. Endocrinology and metabolism.Am J Physiol Endocrinol Metab.2011 Jul 5. [Epub ahead of print]
- The American black bear maintains lean body mass for months without food during winter denning. We asked whether changes in the growth hormone/insulin-like growth factor-I (GH/IGF-I) axis may contribute to this remarkable adaptation to starvation. Serum IGF-I levels were measured by radioimmunoassay
- PMID 21730258
Japanese Journal
- Rapamycin Protects Against High Fat Diet-Induced Obesity in C57BL/6J Mice
- CHANG Geng-Ruei,CHIU Yi-Shin,WU Ying-Ying,CHEN Wen-Ying,LIAO Jiunn-Wang,CHAO Te-Hsin,MAO Frank Chiahung
- Journal of pharmacological sciences 109(4), 496-503, 2009-04-20
- … However, RAPA-treated mice were hyperphagic, demonstrating an increase in food intake. …
- NAID 10025735571
- Fluvoxamine Inhibits Weight Gain and Food Intake in Food Restricted Hyperphagic Wistar Rats(Pharmacology)
- SHINOZAKI Tomokazu,KIMURA Masaki,HOSOYAMADA Makoto,SHIBASAKI Toshiaki
- Biological & pharmaceutical bulletin 31(12), 2250-2254, 2008-12-01
- … The effects of fluvoxamine, a selective serotonin reuptake inhibitor (SSRI), were studied in normophagic and food-restriction-induced hyperphagic middle-aged Wistar rats. … Hyperphagic middle-aged Wistar rats were subjected to 10d of food restriction; …
- NAID 110007005024
Related Links
- hyperphagia /hy・per・pha・gia/ (-fa´jah) polyphagia.hyperpha´gic. hy・per・pha・gia (h p r-f j ). n. Abnormally increased appetite for and consumption of food, thought to be associated with a lesion or injury in the hypothalamus. Hyperphagia ...
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★リンクテーブル★
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- 英
- hyperorexia, hyperphagia、hyperphagic
- 関
- 過食、過食症、食欲亢進、摂食亢進、多食症