関: hyperoxic

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/07/22 23:06:23」(JST)

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Hyperoxia is excess oxygen or higher than normal partial pressure of oxygen.

In medicine, it refers to excess oxygen in the lungs or other body tissues, which can be caused by breathing air or oxygen at pressures greater than normal atmospheric pressure. This kind of hyperoxia can lead to oxygen toxicity.

In the environment, it refers to excess oxygen in a body of water or other habitat.

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1. 酸素毒性 oxygen toxicity
2. 新生児におけるチアノーゼの概要 overview of cyanosis in the newborn
3. 気管支肺異形成症の病因および臨床的特徴 pathogenesis and clinical features of bronchopulmonary dysplasia
4. 高圧酸素療法 hyperbaric oxygen therapy
5. 急性呼吸窮迫症候群：成人における支持療法および酸素供給 acute respiratory distress syndrome supportive care and oxygenation in adults

English Journal

Current trends in paediatric and neonatal ventilatory care - a nationwide survey.

Alander M, Peltoniemi O, Saarela T, Anttila E, Pokka T, Kontiokari T.Source.Department of Pediatrics, Oulu University Hospital, Oulu, Finland .University of Oulu, Oulu, Finland.
Acta paediatrica (Oslo, Norway : 1992).Acta Paediatr.2013 Feb;102(2):123-8. doi: 10.1111/j.1651-2227.2012.02830.x. Epub 2012 Sep 24.
Aim: To assess daily practices in paediatric and neonatal ventilatory care in Finland. Methods: All neonatal and paediatric intensive care units in Finland were sent a questionnaire on ventilatory strategies and were offered a 3-month prospective survey. Results: A total of 96% of units ret
PMID 22957736

Exercise and diet-induced weight loss attenuates oxidative stress related-coronary vasoconstriction in obese adolescents.

Gao Z, Novick M, Muller MD, Williams RJ, Spilk S, Leuenberger UA, Sinoway LI.SourcePenn State Hershey Heart and Vascular Institute, The Milton S. Hershey Medical Center, The Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
European journal of applied physiology.Eur J Appl Physiol.2013 Feb;113(2):519-28. doi: 10.1007/s00421-012-2459-9. Epub 2012 Jul 20.
Obesity is a disease of oxidative stress (OS). Acute hyperoxia (breathing 100 % O(2)) can evoke coronary vasoconstriction by the oxidative quenching of nitric oxide (NO). To examine if weight loss would alter the hyperoxia-related coronary constriction seen in obese adolescents, we measured the cor
PMID 22814577

Normobaric hyperoxia combined with minocycline provides greater neuroprotection than either alone in transient focal cerebral ischemia.

Jin X, Liu J, Liu KJ, Rosenberg GA, Yang Y, Liu W.SourceCollege of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
Experimental neurology.Exp Neurol.2013 Feb;240:9-16. doi: 10.1016/j.expneurol.2012.11.018. Epub 2012 Nov 26.
Normobaric hyperoxia (NBO), which maintains penumbral oxygenation, reduces brain injury during cerebral ischemia, and minocycline, a tetracycline derivative, reduces reperfusion injury, including inflammation, apoptosis and matrix metalloproteinases (MMPs) activation. Since they have different mecha
PMID 23195595

Japanese Journal

高強度運動後の高圧高酸素環境滞在が疲労回復とパフォーマンスに及ぼす影響

竹村英和/内丸仁/高橋弘彦/鈴木省三/
仙台大学紀要 43(1), 9-18, 2011-09-30
NAID 110008658043

TRPA1 underlies a sensing mechanism for O(2).

Takahashi Nobuaki,Kuwaki Tomoyuki,Kiyonaka Shigeki,Numata Tomohiro,Kozai Daisuke,Mizuno Yusuke,Yamamoto Shinichiro,Naito Shinji,Knevels Ellen,Carmeliet Peter,Oga Toru,Kaneko Shuji,Suga Seiji,Nokami Toshiki,Yoshida Jun-Ichi,Mori Yasuo
Nature chemical biology, 2011-08-28
… O(2) sensing is based upon disparate processes: whereas prolyl hydroxylases (PHDs) exert O(2)-dependent inhibition on TRPA1 activity in normoxia, direct O(2) action overrides the inhibition via the prominent sensitivity of TRPA1 to cysteine-mediated oxidation in hyperoxia. … In mice, disruption of the Trpa1 gene abolishes hyperoxia- and hypoxia-induced cationic currents in vagal and sensory neurons and thereby impedes enhancement of in vivo vagal discharges induced by hyperoxia and hypoxia. …
NAID 120003307930