高ガストリン血症
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English Journal
- Weight Gain in Zollinger-Ellison Syndrome After Acid Suppression.
- Riff BP1, Leiman DA, Bennett B, Fraker DL, Metz DC.
- Pancreas.Pancreas.2016 Feb;45(2):193-7. doi: 10.1097/MPA.0000000000000376.
- OBJECTIVES: Zollinger-Ellison syndrome (ZES) is characterized by hypergastrinemia and gastric acid hypersecretion resulting in peptic ulcer disease, diarrhea, and weight loss. Acid secretion can be controlled with medication, and biochemical cure is possible with surgery. Data on how these intervent
- PMID 26164604
- Assessment of Gastric Emptying in Patients with Autoimmune Gastritis.
- Kalkan Ç1, Soykan I2, Soydal Ç3, Özkan E3, Kalkan E1.
- Digestive diseases and sciences.Dig Dis Sci.2016 Jan 2. [Epub ahead of print]
- BACKGROUND AND AIM: Symptoms of patients with autoimmune gastritis are not specific, and some patients may present symptoms suggestive of delayed gastric emptying. This study aims to investigate whether any delay in gastric emptying of solid food exists in patients with autoimmune gastritis and, if
- PMID 26725066
- Safety of proton pump inhibitors and risk of gastric cancers: review of literature and pathophysiological mechanisms.
- Ko Y1, Tang J2, Sanagapalli S1, Kim BS1, Leong RW1.
- Expert opinion on drug safety.Expert Opin Drug Saf.2016 Jan;15(1):53-63. doi: 10.1517/14740338.2016.1118050. Epub 2015 Dec 14.
- INTRODUCTION: Despite being an overall safe drug, several long-term adverse effects are associated with proton pump inhibitors (PPIs). The link between PPI use and gastric neuroendocrine tumors (NETs), gastric adenocarcinomas and Barrett's esophagus progression gastric cancers has been investigated
- PMID 26560097
Japanese Journal
- 高ガストリン血症をともなうB型胃炎を背景とした胃NETの1例
- Hypergastrinemia and a duodenal ulcer caused by gastric duplication
Related Links
- Hypergastrinemia PPI therapy leads to diminished acid secretion, diminished antral D-cell release of somatostatin, consequent increased G-cell release of gastrin and hypergastrinemia. This causes oxyntic ...
- CAUSES There are two major categories of hypergastrinemia: those that are associated with acid hypersecretion and those that are not. Appropriate gastrin secretion occurs with neutral pH, while unopposed gastrin ...
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- 英
- hypergastrinemia
高ガストリン血症をきたす疾患
YN.A-11
- usefull for diagnosis: ゾリンジャー・エリソン症候群、悪性貧血(壁細胞減少)
- often↑: 副甲状腺機能亢進症(Ca↑によりG細胞が刺激される)、尿毒症(ガストリンは腎代謝らしいので、腎機能低下と関連?)、閉塞性黄疸
- sometimes↑: 萎縮性胃炎(固有胃腺の萎縮)、胃・十二指腸潰瘍活動期
QB.A-293
- 慢性腎不全ではガストリンの代謝が障害され高ガストリン血症を来す。
膵・消化管神経内分泌腫瘍診療ガイドライン
- ヘリコバクター・ピロリ感染症、慢性腎不全、萎縮性胃炎などによるG細胞過形成、PPI長期内服