UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Hyperexpansion of Functional Viral-Specific CD8+ T Cells in Lymphopenia-Associated MCMV Pneumonitis.
- Shah PD1, Zhong Q1, Lendermon EA2, Pipeling MR2, McDyer JF2.
- Viral immunology.Viral Immunol.2015 Jun;28(5):255-64. doi: 10.1089/vim.2015.0005. Epub 2015 May 18.
- Cytomegalovirus (CMV) is a significant cause of morbidity and mortality in immunocompromised hosts, many of whom undergo significant periods of lymphopenia. However, the impact of lymphopenia and subsequent immune reconstitution on T cell responses and pulmonary pathology are poorly understood. Usin
- PMID 26046830
- Simplified strategy for rapid first-line screening of fragile X syndrome: closed-tube triplet-primed PCR and amplicon melt peak analysis.
- Rajan-Babu IS1, Law HY2, Yoon CS2, Lee CG3, Chong SS1.
- Expert reviews in molecular medicine.Expert Rev Mol Med.2015 May 4;17:e7. doi: 10.1017/erm.2015.5.
- Premutation and full-mutation hyperexpansion of CGG-triplets in the X-linked Fragile X Mental Retardation 1 (FMR1) gene have been implicated in fragile X-associated tremor/ataxia syndrome, fragile X-associated primary ovarian insufficiency, and fragile X syndrome (FXS), respectively. The currently a
- PMID 25936533
- Mechanism of Action of 2-Aminobenzamide HDAC Inhibitors in Reversing Gene Silencing in Friedreich's Ataxia.
- Soragni E1, Chou CJ1, Rusche JR2, Gottesfeld JM1.
- Frontiers in neurology.Front Neurol.2015 Mar 5;6:44. doi: 10.3389/fneur.2015.00044. eCollection 2015.
- The genetic defect in Friedreich's ataxia (FRDA) is the hyperexpansion of a GAA•TTC triplet in the first intron of the FXN gene, encoding the essential mitochondrial protein frataxin. Histone post-translational modifications near the expanded repeats are consistent with heterochromatin formation a
- PMID 25798128
Related Pictures