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1. 高炭酸ガス血症患者における酸素の使用 use of oxygen in patients with hypercapnia
2. 高二酸化炭素血症の許容（Permissive hypercapnia） permissive hypercapnia
3. 換気調節障害 disorders of ventilatory control
4. 成人における閉塞性睡眠時無呼吸に対する陽圧気道療法の導入 initiation of positive airway pressure therapy for obstructive sleep apnea in adults
5. 成人の急性呼吸不全における非侵襲的陽圧換気 noninvasive positive pressure ventilation in acute respiratory failure in adults

English Journal

Investigating the field-dependence of the Davis model: Calibrated fMRI at 1.5, 3 and 7T.

Hare HV1, Blockley NP2, Gardener AG2, Clare S2, Bulte DP2.
NeuroImage.Neuroimage.2015 May 15;112:189-96. doi: 10.1016/j.neuroimage.2015.02.068. Epub 2015 Mar 14.
Gas calibrated fMRI in its most common form uses hypercapnia in conjunction with the Davis model to quantify relative changes in the cerebral rate of oxygen consumption (CMRO2) in response to a functional stimulus. It is most commonly carried out at 3T but, as 7T research scanners are becoming more
PMID 25783207

Correlation of carotid artery disease severity and vasomotor response of cerebral blood vessels.

Krdžić I1, Čovičković-Šternić N2, Katsiki N3, Isenović ER4, Radak Đ5.
Angiology.Angiology.2015 May;66(5):481-7. doi: 10.1177/0003319714538312. Epub 2014 Jun 5.
We assessed reactivity of cerebral vessels on hypercapnia in patients with carotid occlusive disease. The effects of vascular risk factors on carotid atherosclerosis and vasomotor reactivity (VMR) of cerebral arterioles were also examined. Patients (n = 50) with carotid stenosis (≥30% in 1 or both
PMID 24904181

Regional cerebral hemodynamic response to incremental exercise is blunted in poorly controlled patients with uncomplicated type 1 diabetes.

Tagougui S1, Fontaine P2, Leclair E3, Aucouturier J1, Matran R4, Oussaidene K1, Descatoire A5, Prieur F6, Mucci P1, Vambergue A2, Baquet G1, Heyman E7.
Diabetes care.Diabetes Care.2015 May;38(5):858-67. doi: 10.2337/dc14-1792. Epub 2015 Feb 9.
OBJECTIVE: Cerebral vasoreactivity to pharmacologically induced hypercapnia is impaired in poorly controlled patients with type 1 diabetes but otherwise free from microangiopathy. However, whether this response is also compromised during exercise, a daily-life physiological condition challenging reg
PMID 25665816

加藤貴英
豊田工業高等専門学校研究紀要 46, 87-90, 2014-01-31
… The aim of this study was to investigate the effect of intermittent hypoxic and hypercapnic gas inhalation on the breath hold time (BHT). … The subject breathed hypoxic and hypercapnic gas (O2: 12%, CO2: 6%, N2: balance) 1 hour per day for 1 week. … Although one subject's data, this study's result suggested that intermittent hypoxic and hypercapnic gas inhalation 1 hour per day for 1 week may promote the BHT of a novice breath hold diver. …
NAID 110009660883

Early Onset of Ventilatory and Airway Response to Hypercapnia is Mediated by Medullary 5-HT1A Receptors in Infant Rats

MATSUDAIRA Shingo,KANAMARU Mitsuko,IIZUKA Makito,HOMMA Ikuo,IZUMIZAKI Masahiko
The Showa University Journal of Medical Sciences 26(3), 211-217, 2014
… 5-HT release in the DMM and hypercapnic ventilatory and airway responses increased dose dependently with CO2 concentration during both aCSF and WAY-100635 perfusion, with no difference between groups. … Blunted early onset of hypercapnic ventilatory and airway responses may be one cause of SIDS. …
NAID 130004841525

石原唯史,神薗淳司,松島卓也,市川光太郎
日本救急医学会雑誌 25(4), 135-140, 2014
【緒言】救急搬送の要因として頻度が高い小児痙攣には，安全な気道確保と呼吸状態の正確な把握のもと酸素投与と換気補助が不可欠である。高CO2血症が意識障害の遷延の原因につながる報告もあり，痙攣時にも同様のことが考えられうるため，高CO2血症のリスク因子を検討することを目的とした。【対象と方法】2008年1月から2010年12月までの3年間に痙攣を主訴に救急搬送された患児の静脈血液ガス検査を後方視的に検 …
NAID 130004841008