hydroxyethylpromethazine

ヒドロキシエチルプロメタジン

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/16 20:16:06」(JST)

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Hydroxyethylpromethazine

Systematic (IUPAC) name
N-(2-hydroxyethyl)-N,N-dimethyl-1-(10H- phenothiazin-10-yl)propan-2-aminium
Clinical data
Identifiers
CAS Registry Number	7647-63-4
ATC code	R06AD05
PubChem	CID 16406
ChemSpider	15559 Y
UNII	571559SLAJ Y
Chemical data
Formula	C19H25N2OS+
Molecular mass	329.48 g/mol
SMILES OCC[N+](C)(C)C(C)CN1c3c(Sc2c1cccc2)cccc3
InChI InChI=1S/C19H25N2OS/c1-15(21(2,3)12-13-22)14-20-16-8-4-6-10-18(16)23-19-11-7-5-9-17(19)20/h4-11,15,22H,12-14H2,1-3H3/q+1  Y Key:PDSVTRQOBUIQBQ-UHFFFAOYSA-N  Y
Y (what is this?)  (verify)

Hydroxyethylpromethazine is an antihistamine with anticholinergic properties. It is structurally analogous to promethazine.

See also

• Promethazine

References

English Journal

• Comparison of the antihistaminic effects in skin of a tertiary (promethazine) and a quarternary phenothiazine (N-hydroxyethylpromethazine).

• Hägermark O, Strandberg K.
• Acta allergologica.Acta Allergol.1974 Dec;29(6):462-8.
• PMID 4155913

• Effect of N-hydroxyethylpromethazine (Aprobit) on the tissue distribution and excretion of 35S-chlorpromazine in cats.

• Neuvonen PJ, Idanpään-Heikkilä JE, Vapaatalo HI.
• European journal of pharmacology.Eur J Pharmacol.1968 Feb;2(4):320-2.
• PMID 4384451

• Effect on N-hydroxyethylpromethazine (Aprobit) on the distribution of 35S-chlorpromazine studied by autoradiography in cats and mice.

• Idänpään-Heikkilä JE, Vapaatalo HI, Neuvonen PJ.
• Psychopharmacologia.Psychopharmacologia.1968;13(1):1-13.
• PMID 4386346

Related Links

• Hydroxyethylpromethazineとは - goo Wikipedia (ウィキペディア)

Hydroxyethylpromethazineとは？goo Wikipedia (ウィキペディア) 。出典：Wikipedia（ウィキペディア）フリー百科事典。 Hydroxyethylpromethazineとは - goo Wikipedia (ウィキペディア) gooトップ サイトマップ スタートページに設定 RSS ...

• hydroxyethylpromethazine - Wiktionary

hydroxyethylpromethazine (uncountable) Wikipedia has an article on: hydroxyethylpromethazine Wikipedia (pharmacology) A promethazine derivative used as an antihistamine. Translations [] medicine Finnish: Retrieved from " " : ...

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hydroxyethylpromethazine