English Journal

The neonicotinoid imidacloprid, and the pyrethroid deltamethrin, are antagonists of the insect Rdl GABA receptor.

Taylor-Wells J1, Brooke BD2,3, Bermudez I1, Jones AK1.
Journal of neurochemistry.J Neurochem.2015 Aug 22. doi: 10.1111/jnc.13290. [Epub ahead of print]
A mutation in the second transmembrane domain of the GABA receptor subunit, Rdl, is associated with resistance to insecticides such as dieldrin and fipronil. Molecular cloning of Rdl cDNA from a strain of the malaria mosquito, Anopheles gambiae, which is highly resistant to dieldrin revealed this mu
PMID 26296809

Heteromultimerization of prokaryotic bacterial cyclic nucleotide-gated (bCNG) ion channels, members of the mechanosensitive channel of small conductance (MscS) superfamily.

Malcolm HR1, Heo YY, Elmore DE, Maurer JA.
Biochemistry.Biochemistry.2014 Dec 30;53(51):8005-7. doi: 10.1021/bi501118c. Epub 2014 Dec 16.
Traditionally, prokaryotic channels are thought to exist as homomultimeric assemblies, while many eukaryotic ion channels form complex heteromultimers. Here we demonstrate that bacterial cyclic nucleotide-gated channels likely form heteromultimers in vivo. Heteromultimer formation is indicated throu
PMID 25493556

Structural similarity of secretins from type II and type III secretion systems.

Tosi T1, Estrozi LF1, Job V1, Guilvout I2, Pugsley AP2, Schoehn G3, Dessen A4.
Structure (London, England : 1993).Structure.2014 Sep 2;22(9):1348-55. doi: 10.1016/j.str.2014.07.005. Epub 2014 Aug 21.
Secretins, the outer membrane components of several secretion systems in Gram-negative bacteria, assemble into channels that allow exoproteins to traverse the membrane. The membrane-inserted, multimeric regions of PscC, the Pseudomonas aeruginosa type III secretion system secretin, and PulD, the Kle
PMID 25156426

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homomultimeric - Wiktionary

homomultimeric Definition from Wiktionary, the free dictionary Jump to: navigation, search English [edit] Adjective [edit] homomultimeric (not comparable) (biochemistry) Describing a protein containing two or more identical polypeptide chains

HOMOMULTIMERIC STRUCTURE BY ASSEMBLY OF ...

The present invention relates to a homomultimeric protein structure constituted by assembled monomers of the P98 protein of Sulfolobus islandicus rod-shaped virus 2 (SIRV2) or assembled monomer variants of said P98 protein. In a ...