WordNet

incompatibility in which one persons tissue cannot be transplanted to another person

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Targeted Disruption of the β2-Microglobulin Gene Minimizes the Immunogenicity of Human Embryonic Stem Cells.

Wang D1, Quan Y2, Yan Q2, Morales JE2, Wetsel RA1.
Stem cells translational medicine.Stem Cells Transl Med.2015 Oct;4(10):1234-45. doi: 10.5966/sctm.2015-0049. Epub 2015 Aug 18.
: Human embryonic stem cells (hESCs) are a promising source of cells for tissue regeneration, yet histoincompatibility remains a major challenge to their clinical application. Because the human leukocyte antigen class I (HLA-I) molecules are the primary mediators of immune rejection, we hypothesized
PMID 26285657

Induced pluripotent stem cells and their use in cardiac and neural regenerative medicine.

Skalova S1, Svadlakova T2, Shaikh Qureshi WM3, Dev K4, Mokry J5.
International journal of molecular sciences.Int J Mol Sci.2015 Feb 13;16(2):4043-67. doi: 10.3390/ijms16024043.
Stem cells are unique pools of cells that are crucial for embryonic development and maintenance of adult tissue homeostasis. The landmark Nobel Prize winning research by Yamanaka and colleagues to induce pluripotency in somatic cells has reshaped the field of stem cell research. The complications re
PMID 25689424

Achieving incompatible transplantation through desensitization: current perspectives and future directions.

Jordan SC1, Choi J, Vo A.
Immunotherapy.Immunotherapy.2015;7(4):377-98. doi: 10.2217/imt.15.10.
The application of life-saving transplantation is severely limited by the shortage of organs, and histoincompatibility. To increase transplant rates in sensitized patients, new protocols for HLA and blood type incompatible (ABOi) desensitization have emerged. These approaches require significant des
PMID 25917629

Development of an Ideal and Potent Cancer Immunotherapy Designed by Consideration of HLA Polymorphism

冨田雄介,千住覚,入江厚,西村泰治
Major Histocompatibility Complex 20(1), 45-56, 2013
… To further improve the effectiveness of the TAA-targeted cancer immunotherapy, we identified TAA-derived peptides that can stimulate both TAA-specific CTL and helper T (Th) cells, and developed genetically modified allogeneic iPS cell-derived dendritic cell-mediated immunotherapy that can overcome the potential problems of histoincompatibility between iPS cell donors and cancer patients. …
NAID 130004647538

Colonial Allorecognition, Hemolytic Rejection, and Viviparity in Botryllid Ascidians

Hirose Euichi
Zoological science 20(4), 387-394, 2003-04-25
… The limited distribution of allorecognition sites would be a solution to the embryo-parent histoincompatibility in viviparity. …
NAID 110006162714