Determination of inositol hexanicotinate in rat plasma by high performance liquid chromatography with UV detection.
Liang D, Ma J, Wei B, Poon IO, Bell EC, Bates TR.SourceDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004, USA. liang_dx@tsu.edu
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.J Chromatogr B Analyt Technol Biomed Life Sci.2008 Feb 15;863(1):172-6. Epub 2008 Jan 4.
A HPLC method with UV detection at 262nm was developed to analyze inositol hexanicotinate in rat plasma. Plasma samples were extracted with an equal volume of acetonitrile, followed by dilution with mobile phase buffer (5mM phosphate buffer, pH 6.0) to eliminate any solvent effects. Inositol hexanic
Similarity of the effects of erythritol and xylitol on some risk factors of dental caries.
Makinen KK, Saag M, Isotupa KP, Olak J, Nommela R, Soderling E, Makinen PL.SourceInstitute of Dentistry, University of Turku, Lemminkaisenkatu 2, FI-20520 Turku, Finland.
Several sugar alcohols (polyols) have been promoted as potential sugar substitutes in caries limitation. However, differences in the effects of simple alditol-type sugar alcohol homologues on dental plaque have not been compared in clinical tests. The effects of 6-month use of erythritol (a sugar al
… The anesthetized rats were immersed into the water bath at 15℃ to the depth of xiphoid process for 10 min. Under these conditions, the changes of DBF by the application of the reference drugs (norepinephrine, dl-α-tocopheryl nicotinate, inositol hexanicotinate, isoxsuprine hydrochloride) were measured accurately. …
Solvolyses of Polyhydric Alcohol Esters. I. Stability of meso-Inositol Hexanicotinate in Acidic Medium
鈴木 徳治,谷村 勇一
Chemical & pharmaceutical bulletin 17(7), 1422-1431, 1969-07-25
… The quantitative procedure of nicotinic acid liberated from meso-inositol hexanicotinate (IHN) and several nicotinic acid esters of polyhydric alcohols and the stability in acidic solution were investigated to predict the gastric stability for a possible explanation of their absorption from the gastrointestinal tract. …
One form of dietary supplement is inositol hexanicotinate (IHN), which is inositol that has been esterified with niacin on all six of inositol's alcohol groups. IHN is usually sold as "flush-free" or "no-flush" ...