hemihypertrophy

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/07/04 19:30:49」(JST)

wiki en

[Wiki en表示]

Hemihypertrophy is a disease in which one side of the body or a part of one side is larger than the other. Isolated hemihypertrophy, now called isolated hemihyperplasia, is a congenital overgrowth disorder associated with an increased risk for embryonal tumors, mainly Wilms tumor and hepatoblastoma. Children with hemihypertrophy may also develop scoliosis, a curvature of the spine. There are two main surgical options for the treatment of hemihypertrophy, shortening and lengthening. Epiphysiodesis, which involves removing part of the growth plate of the longer leg, allowing the shorter leg to "catch up", is performed on patients still able to grow. Bone resection is performed on patients who have no growth left and involves removing part of the bone. Leg lengthening procedures are more painful, involving the insertion of pins to be turned, moving parts of the bone apart. This process is reserved mainly for patients with a discrepancy greater than 4 cm, although some leg lengthening procedures are now done cosmetically. Non-surgical options include attachment of a lift to the shoe, allowing the patient to walk normally. Hemifacial hyperplasia is believed to be a minor form of hemihypertrophy.

References

External links

• Hemihypertrophy entry in the public domain NCI Dictionary of Cancer Terms
• [1] entry in the Children's Hospital of Boston website

 This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. ベックウィズ・ヴィーデマン症候群 beckwith wiedemann syndrome
• 2. ウィルムス腫瘍の症状、診断、および病期分類 presentation diagnosis and staging of wilms tumor
• 3. 限局性結節性過形成 focal nodular hyperplasia
• 4. 低身長の原因 causes of short stature
• 5. 跛行を呈する小児に対するアプローチ approach to the child with a limp

English Journal

• Jumping translocation of 15q24-qter resulting in partial trisomy: A case report.

• Czakó M, Hadzsiev K, Melegh B, Kosztolányi G.AbstractWe report on a jumping translocation with five different cell lines detected in four tissues in a 2-year-old patient. This rare type of chromosomal abnormality (not more than 30 cases published so far) proved to be a series of non-reciprocal translocations of the 15q24-qter donor chromosome segment to the telomeric region of chromosomes 5q, 10q, 16q and 19p, respectively. The process, in addition to a few cells without translocation, resulted in partial trisomy of 15q24-qter which was associated with somatic overdevelopment in the patient, with hemihypertrophy and minor anomalies. The phenotype of our patient was different from that of the other two patients found in the literature having the same donor chromosome segment involved in a similar rearrangement. Possibly, the difference in the phenotype lies in the various ratios of somatic mosaicism with five cell lines, in particular the presence of normal one which is extremely rare in patients with jumping translocation. Here we discuss the various ways on how the rearrangement could arise.
• Gene.Gene.2012 Apr 21. [Epub ahead of print]
• We report on a jumping translocation with five different cell lines detected in four tissues in a 2-year-old patient. This rare type of chromosomal abnormality (not more than 30 cases published so far) proved to be a series of non-reciprocal translocations of the 15q24-qter donor chromosome segment
• PMID 22546223

• Incidence of abdominal tumors in syndromic and idiopathic hemihypertrophy/isolated hemihyperplasia.

• Dempsey-Robertson M, Wilkes D, Stall A, Bush P.SourceDepartment of Radiology, Texas Scottish Rite Hospital for Children, Dallas, TX 75219, USA. molly.dempsey-robertson@tsrh.org
• Journal of pediatric orthopedics.J Pediatr Orthop.2012 Apr-May;32(3):322-6.
• BACKGROUND: There is a reported increased risk of intra-abdominal tumors in children with both syndromic (SH) and isolated idiopathic hemihyperplasia (IH). Recommendations for tumor surveillance have been made, although there is no consensus for frequency and duration of screening. Our objective was
• PMID 22411341

Japanese Journal

• 片側肥大症に発生した手根管症候群の1例

• 下江 隆司,谷口 泰徳,北野 岳史,山中 学,辻本 修平,吉田 宗人
• 中部日本整形外科災害外科学会雑誌. 中部日本整形外科災害外科学会抄録 54(2), 317-318, 2011-03-01
• NAID 10029071839

• 片側過成長による脚長不等-抑制か延長か-ステープルによる骨端線成長抑制効果の検討

• 服部 義,北小路 隆彦,伊藤 弘紀
• 日本創外固定・骨延長学会雑誌 = The journal of the Japanese Association of External Fixation and Limb Lengthening 21, 179, 2010-01-13
• NAID 10027253093

Related Links

• Hemihypertrophy - Wikipedia, the free encyclopedia

Hemihypertrophy is a condition in which one side of the body or a part of one side is larger than the other. Children with hemihypertrophy have an increased risk of developing certain types of cancer, including Wilms tumor (a childhood kidney ...

• Hemihypertrophy (Hemihyperplasia) | Definition and Patient ...

Hemihypertrophy, more correctly termed hemihyperplasia, is defined as the enlargement of one side of the body or part of the body.

Related Pictures

---

★リンクテーブル★

リンク元

「片側肥大症」

「片側肥大症」

　　[★]

英

hemihypertrophy

同

半側肥大症 unilateral hypertrophy、片側巨大症 hemimacrosomia、半側巨人症 hemigigantism