関: angioblast、angioblastic、angioblastic cell、hemangioblast

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/04/15 12:16:46」(JST)

wiki en

For the location in the video game The Curse of Monkey Island, see Blood Island (The Curse of Monkey Island).

Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system.

They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium.

The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide.

Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta.

References

This article incorporates text from a public domain edition of Gray's Anatomy.

External links

Embryology at Temple Heart98/heart97a/sld008
"Development of the vascular system" at brown.edu
http://embryology.med.unsw.edu.au/Notes/heart20.htm

This developmental biology article is a stub. You can help Wikipedia by expanding it.

English Journal

Fgf differentially controls cross-antagonism between cardiac and haemangioblast regulators.

Simoes FC, Peterkin T, Patient R.SourceMRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Oxford University, John Radcliffe Hospital, Headington OX3 9DS, UK.
Development (Cambridge, England).Development.2011 Aug;138(15):3235-45.
Fibroblast growth factor (Fgf) has been implicated in the control of heart size during development, although whether this is by controlling cell fate, survival or proliferation has not been clear. Here, we show that Fgf, without affecting survival or proliferation, acts during gastrulation to drive
PMID 21750034

Haemogenic endothelium in infantile haemangioma.

Itinteang T, Tan ST, Brasch H, Day DJ.SourceSchool of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand.
Journal of clinical pathology.J Clin Pathol.2010 Nov;63(11):982-6. Epub 2010 Oct 5.
BACKGROUND: Proliferating infantile haemangioma (IH) is a tumour of the microvasculature composed predominantly of immature endothelial cells. The origin of IH is unclear, but it has been shown to express markers of both endothelial and haematopoietic lineages, and a role for endothelial progenitor
PMID 20924092