グリムタンパク質
WordNet
- not to be placated or appeased or moved by entreaty; "grim determination"; "grim necessity"; "Russias final hour, it seemed, approached with inexorable certainty"; "relentless persecution"; "the stern demands of parenthood" (同)inexorable, relentless, stern, unappeasable, unforgiving, unrelenting
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
PrepTutorEJDIC
- (顔つき・態度などが)『険しい』,こわい / 『断固とした』,妥協を許さない / 《話》ぞっとする,不快な / 容赦のない,すさまじい
- 蛋白(たんばく)質
UpToDate Contents
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English Journal
- Apoptosis signal-regulating kinase 1 exhibits oncogenic activity in pancreatic cancer.
- Luo Y1,2, Gao S2, Hao Z2, Yang Y2, Xie S1, Li D2, Liu M1, Zhou J1,2.
- Oncotarget.Oncotarget.2016 Sep 17. doi: 10.18632/oncotarget.12090. [Epub ahead of print]
- Pancreatic cancer has an extremely grim prognosis, with an overall 5-year survival rate less than 5%, as a result of its rapid metastasis and late diagnosis. To combat this disease, it is crucial to better understand the molecular mechanisms that contribute to its pathogenesis. Herein, we report tha
- PMID 27655673
- GhMCS1, the Cotton Orthologue of Human GRIM-19, Is a Subunit of Mitochondrial Complex I and Associated with Cotton Fibre Growth.
- Dong CJ1, Wu AM1, Du SJ1, Tang K1, Wang Y1, Liu JY1.
- PloS one.PLoS One.2016 Sep 15;11(9):e0162928. doi: 10.1371/journal.pone.0162928. eCollection 2016.
- GRIM-19 (Gene associated with Retinoid-Interferon-induced Mortality 19) is a subunit of mitochondrial respiratory complex I in mammalian systems, and it has been demonstrated to be a multifunctional protein involved in the cell cycle, cell motility and innate immunity. However, little is known about
- PMID 27632161
- Inducing a humoral immune response to pancreatic cancer antigen.
- Seifert M1, Seifert G2, Wolff-Vorbeck G2, Langenmair E2, Hopt UT2, Wittel UA2.
- Cellular immunology.Cell Immunol.2016 Sep 6. pii: S0008-8749(16)30091-0. doi: 10.1016/j.cellimm.2016.09.002. [Epub ahead of print]
- BACKGROUND: Patients with pancreatic carcinoma have a grim prognosis. Here, we examine the induction of an in vitro antibody response of human B cells to pancreatic carcinoma antigens.MATERIAL AND METHODS: Cells of five cultured pancreatic ductal adenocarcinoma lines were lysed and their plasma memb
- PMID 27663207
Japanese Journal
- GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I
- Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis
Related Links
- 1. EMBO J. 2015 Jan 2;34(1):55-66. doi: 10.15252/embj.201488582. Epub 2014 Nov 14. GRIM REAPER peptide binds to receptor kinase PRK5 to trigger cell death in Arabidopsis. Wrzaczek M(1), Vainonen JP(2), Stael S ...
- 1. Genes Dev. 1996 Jul 15;10(14):1773-82. grim, a novel cell death gene in Drosophila. Chen P(1), Nordstrom W, Gish B, Abrams JM. Author information: (1)Department of Cell Biology and Neuroscience, University of Texas ...
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