WordNet
- inflammation of the brain usually caused by a virus; symptoms include headache and neck pain and drowsiness and nausea and fever (`phrenitis is no longer in scientific use) (同)cephalitis, phrenitis
- relating to or characterized by granulomas
PrepTutorEJDIC
- 脳炎
UpToDate Contents
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- 1. 自由生活アメーバ free living amebas
English Journal
- Assessment of blood-brain barrier penetration of miltefosine used to treat a fatal case of granulomatous amebic encephalitis possibly caused by an unusual Balamuthia mandrillaris strain.
- Roy SL1, Atkins JT, Gennuso R, Kofos D, Sriram RR, Dorlo TP, Hayes T, Qvarnstrom Y, Kucerova Z, Guglielmo BJ, Visvesvara GS.
- Parasitology research.Parasitol Res.2015 Sep 2. [Epub ahead of print]
- Balamuthia mandrillaris, a free-living ameba, causes rare but frequently fatal granulomatous amebic encephalitis (GAE). Few patients have survived after receiving experimental drug combinations, with or without brain lesion excisions. Some GAE survivors have been treated with a multi-drug regimen in
- PMID 26329128
- Acanthamoeba castellanii Proteases are Capable of Degrading Iron-Binding Proteins as a Possible Mechanism of Pathogenicity.
- Ramírez-Rico G1, Martínez-Castillo M2, de la Garza M1, Shibayama M2, Serrano-Luna J1.
- The Journal of eukaryotic microbiology.J Eukaryot Microbiol.2015 Sep;62(5):614-22. doi: 10.1111/jeu.12215. Epub 2015 Mar 23.
- Acanthamoeba castellanii, a free-living amoeba, is an amphizoic organism that can behave as an opportunistic pathogen, causing granulomatous amoebic encephalitis in immunocompromised patients or infecting immunocompetent individuals via cutaneous lesions, sinusoidal infections, or amoebic keratitis.
- PMID 25737266
- Pathogenesis of amoebic encephalitis: Are the amoebae being credited to an 'inside job' done by the host immune response?
- Baig AM1.
- Acta tropica.Acta Trop.2015 Aug;148:72-6. doi: 10.1016/j.actatropica.2015.04.022. Epub 2015 Apr 27.
- Pathogenic free living amoeba like Naegleria fowleri, Acanthamoeba spp., and Balamuthia mandrillaris are known to cause fatal "amoebic meningoencephalitis" by acquiring different route of entries to the brain. The host immune response to these protist pathogens differs from each another, as evidence
- PMID 25930186
Japanese Journal
- The clinicopathological study of granulomatous amebic encephalitis
- Neuropathology : official journal the Japanese Society of Neuropathology 23, 46, 2003-05-01
- NAID 10010738268
Related Links
- Unfortunately, at this point in time it is unclear what steps one can take to prevent Granulomatous Amebic Encephalitis (GAE) and disseminated infection, both of which are very rare. Since persons with weakened ...
- Symptoms of Granulomatous amebic encephalitis The list of signs and symptoms mentioned in various sources for Granulomatous amebic encephalitis includes the 11 symptoms listed below: Headaches Stiff neck Nausea Vomiting
Related Pictures
★リンクテーブル★
| リンク元 | 「肉芽腫性アメーバ性脳炎」「GAE」 |
| 関連記事 | 「granulomatous」「amebic」 |
「肉芽腫性アメーバ性脳炎」
- 病原体：Acanthamoeba属、Balamuthia mandrillaris
- 侵入門戸：経口的、外傷部位。近年臓器移植での感染例が報告されている。
- 経過：数ヶ月程度(慢性/亜急性)
- 予後：致死的
- リスク因子：免疫低下。ただしBalamuthia感染は健常人にも起こりうる
- 免疫学：健康人はAcanthamoebaとBalamuthiaにある程度の抗体価を有す。日常的な暴露が想定される。
参考
- 1.
「GAE」
[★] 肉芽腫性アメーバ性脳炎, granulomatous amebic encephalitis
「granulomatous」
- adj.
- 肉芽腫性の、肉芽腫の
「amebic」
- アメーバ性の
- 関
- amoebic