glycogenolytic

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Model analysis of the relationship between intracellular PO2 and energy demand in skeletal muscle.

Spires J, Gladden LB, Grassi B, Saidel GM, Lai N.SourceDept. of Biomedical Engineering, Case Western Reserve Univ., 10900 Euclid Ave., Wickenden Bldg. Rm. 524, Cleveland, OH 44106-7207. nicola.lai@case.edu.
American journal of physiology. Regulatory, integrative and comparative physiology.Am J Physiol Regul Integr Comp Physiol.2012 Dec;303(11):R1110-26. doi: 10.1152/ajpregu.00106.2012. Epub 2012 Sep 12.
On the basis of experimental studies, the intracellular O(2) (iPo(2))-work rate (WR) relationship in skeletal muscle is not unique. One study found that iPo(2) reached a plateau at 60% of maximal WR, while another found that iPo(2) decreased linearly at higher WR, inferring capillary permeability-su
PMID 22972834

Ali SA, Aly HF, Faddah LM, Zaidi ZF.SourceSanaa Ahmed Ali, Hanan Farouk Aly, Department of Therapeutic Chemistry, Division of Pharmaceutical and Drug Industries, National Research Center, Cairo 12622, Egypt.
World journal of gastroenterology : WJG.World J Gastroenterol.2012 Nov 28;18(44):6379-86. doi: 10.3748/wjg.v18.i44.6379.
The present study aims to clarify the protective effect of supplementation with some antioxidants, such as idebenone (200 mg/kg, ip), melatonin (10 mg/kg, ip) and arginine (200 mg/kg, ip) and their combination, on liver function (T. protein, albumin, alanine aminotransferase, aspartate aminotransfer
PMID 23197883

Combination of N-Methyl-1-Deoxynojirimycin and Ischemic Preconditioning Markedly Reduces the Size of Myocardial Infarcts in Rabbits

Wu Der-Jinn,Minatoguchi Shinya,Uno Yoshihiro,Arai Masazumi,Wang Ningyuan,Nishida Yoshio,Hashimoto Kazuaki,Hashimoto Yasuko,Takemura Genzou,Fujiwara Takako,Fujiwara Hisayoshi
Japanese circulation journal 65(7), 673-677, 2001-06-20
… N-methyl-1-deoxynojirimycin (NMDN), an α-glucosidase inhibitor, reduces myocardial infarct size by reducing the glycogenolytic rate through inhibition of the α-1, 6-glucosidase of glycogen-debranching enzyme in the heart, in addition to possessing an antihyperglycemic action by blocking α-1, 4-glucosidase in the intestine. … Ischemic preconditioning (PC), which markedly reduces the size of the myocardial infarct, is known to reduce the activity of phosphorylase and reduce the glycogenolytic rate. …
NAID 110002568060