グリクロピラミド
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/06 07:51:41」(JST)
[Wiki en表示]
Glyclopyramide
|
| Systematic (IUPAC) name |
|
4-chloro-N-[(pyrrolidin-1-ylamino)carbonyl]benzenesulfonamide
|
| Clinical data |
| Legal status |
|
Routes of
administration |
Oral |
| Identifiers |
| CAS Number |
631-27-6 N |
| ATC code |
None |
| PubChem |
CID: 71793 |
| ChemSpider |
64820 N |
| UNII |
KE474IKG1W Y |
| KEGG |
D01799 Y |
| Chemical data |
| Formula |
C11H14ClN3O3S |
| Molecular mass |
303.76 g/mol |
SMILES
-
C1CCN(C1)NC(=O)NS(=O)(=O)C2=CC=C(C=C2)Cl
|
InChI
-
InChI=1S/C11H14ClN3O3S/c12-9-3-5-10(6-4-9)19(17,18)14-11(16)13-15-7-1-2-8-15/h3-6H,1-2,7-8H2,(H2,13,14,16) N
-
Key:HNSCCNJWTJUGNQ-UHFFFAOYSA-N N
|
| N (what is this?) (verify) |
Glyclopyramide (INN, marketed under the tradename Deamelin-S) is a sulfonylurea drug used in the treatment of diabetes. It has been marketed in Japan since 1965.
It is classified as second generation.[1]
References
- ^ Ozawa H, Murai Y, Ozawa T (2003). "[A 50-year history of new drugs in Japan-the development and progress of anti-diabetic drugs and the epidemiological aspects of diabetes mellitus]". Yakugaku Zasshi (in Japanese) 38 (1): 11–27. PMID 14570054.
- (Japanese) Deamelin-S 250 mg Tablets
|
Oral anti-diabetic drugs and Insulin analogs (A10)
|
|
| Insulin |
| Sensitizers |
| Biguanides |
- Metformin#
- Buformin‡
- Phenformin‡
|
|
| TZDs/"glitazones" (PPAR) |
- Ciglitazone§
- Darglitazone§
- Englitazone§
- Lobeglitazone
- Netoglitazone§
- Pioglitazone
- Rivoglitazone†
- Rosiglitazone
- Troglitazone‡
|
|
| Dual PPAR agonists |
- Aleglitazar†
- Muraglitazar§
- Saroglitazar
- Tesaglitazar§
|
|
|
| Secretagogues |
| K+ ATP |
| Sulfonylureas |
- 1st generation: Acetohexamide
- Carbutamide
- Chlorpropamide
- Metahexamide
- Tolbutamide
- Tolazamide
- 2nd generation: Glibenclamide (Glyburide)#
- Glibornuride
- Glipizide
- Gliquidone
- Glisoxepide
- Glyclopyramide
- Glimepiride
- Gliclazide
|
|
| Meglitinides/"glinides" |
- Nateglinide
- Repaglinide
- Mitiglinide
|
|
|
| GLP-1 agonists |
- Exenatide
- Liraglutide
- Taspoglutide†
- Albiglutide†
- Lixisenatide
- Dulaglutide
- Semaglutide
|
|
| DPP-4 inhibitors |
- Alogliptin
- Anagliptin
- Gemigliptin
- Linagliptin
- Omarigliptin
- Saxagliptin
- Sitagliptin
- Teneligliptin
- Vildagliptin
|
|
| GPR40 Free fatty acid receptor 1 |
|
|
|
| Analogs/other insulins |
- fast-acting (Insulin lispro
- Insulin aspart
- Insulin glulisine)
- short-acting (Regular insulin)
- long-acting (Insulin glargine
- Insulin detemir
- NPH insulin)
- ultra-long-acting (Insulin degludec†)
- inhalable Exubera
- Afrezza
|
|
|
| Other |
| Alpha-glucosidase inhibitors |
- Acarbose
- Miglitol
- Voglibose
|
|
| Amylin analog |
|
|
| Gliflozins |
- Canagliflozin
- Dapagliflozin
- Empagliflozin
- Remogliflozin§
- Sergliflozin§
- Tofogliflozin†
|
|
| Other |
- Bromocriptine
- Benfluorex‡
- Tolrestat‡
|
|
|
-
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
|
|
|
Index of hormones
|
|
| Description |
- Glands
- Hormones
- thyroid
- mineralocorticoids
- Physiology
- Development
|
|
| Disease |
- Diabetes
- Congenital
- Neoplasms and cancer
- Other
- Symptoms and signs
|
|
| Treatment |
- Procedures
- Drugs
- calcium balance
- corticosteroids
- oral hypoglycemics
- pituitary and hypothalamic
- thyroid
|
|
|
English Journal
- [A 50-year history of new drugs in Japan-the development and progress of anti-diabetic drugs and the epidemiological aspects of diabetes mellitus].
- Ozawa H1, Murai Y, Ozawa T.
- Yakushigaku zasshi. The Journal of Japanese history of pharmacy.Yakushigaku Zasshi.2003;38(1):11-27.
- The development and progress of antidiabetic drugs (e.g., insulin preparations and hypoglycemic drugs) are retrospectively investigated in Japan. Their influences on the treatment of diabetes mellitus (DM) and its epidemiological aspects are also discussed. 1) Insulin preparations: Insulin was intro
- PMID 14570054
- Clinical evaluation of the effect of glyclopyramide in diabetes mellitus.
- Yamagata S, Goto Y, Oneda A, Kikuchi J, Toyota T.
- The Tohoku journal of experimental medicine.Tohoku J Exp Med.1969 Jun;98(2):155-69.
- PMID 5811101
Japanese Journal
- 酒井 清,中谷 真理子,山崎 みどり
- 藥學雜誌 101(4), 354-359, 1981-04-25
- … Buformin hydrochloride, glymidine sodium and glyclopyramide were used as a hypoglycemic agent. …
- NAID 110003650156
- Permeation of Sulfonylureas through Cellulose and Dimethylpolysiloxane Membranes
- 上田 晴久,南部 直樹,永井 恒司
- Chemical & pharmaceutical bulletin 29(4), 1140-1146, 1981-04-25
- … In the case of dimethylpolysiloxane membrane, at pH 2,the permeability constants, P, of tolbutamide, chlorpropamide, glyclopyramide and tolazamide were 16.15,5.13,2.33 and 0.95×10^<-8> …
- NAID 110003633791
Related Links
- Definition of Glyclopyramide ... Common Diseases Swine Flu - Updates and information on H1N1 2009 (AKA Swine Influenza) pandemic. Ankylosing spondylitis - Current protocols for diagnosis and treatment options.
- Structure, properties, spectra, suppliers and links for: Glyclopyramide, 631-27-6. ... Predicted data is generated using the US Environmental Protection Agency’s EPISuite Log Octanol-Water Partition Coef (SRC): Log Kow ...
Related Pictures
