WordNet
- a steroid hormone that is produced by the adrenal cortex of animals; affects functioning of gonads and has anti-inflammatory activity
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English Journal
- The utility of three different methods for measuring urinary 18-hydroxycortisol in the differential diagnosis of suspected primary hyperaldosteronism.
- Reynolds RM1, Shakerdi LA, Sandhu K, Wallace AM, Wood PJ, Walker BR.Author information 1Endocrinology Unit, School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK. r.reynolds@ed.ac.ukAbstractOBJECTIVE: Urine 18-hydroxycortisol (18-OHF) measurements are claimed to discriminate between primary hyperaldosteronism due to Conn's syndrome/adrenal adenoma or idiopathic bilateral adrenal hyperplasia (BAH), and also to identify cases of glucocorticoid-suppressible hyperaldosteronism (GSH). We have evaluated three urine 18-OHF methods using a panel of urine samples from patients with hypertension.
- European journal of endocrinology / European Federation of Endocrine Societies.Eur J Endocrinol.2005 Jun;152(6):903-7.
- OBJECTIVE: Urine 18-hydroxycortisol (18-OHF) measurements are claimed to discriminate between primary hyperaldosteronism due to Conn's syndrome/adrenal adenoma or idiopathic bilateral adrenal hyperplasia (BAH), and also to identify cases of glucocorticoid-suppressible hyperaldosteronism (GSH). We ha
- PMID 15941931
- Primary aldosteronism--actual epidemics or false alarm?
- Gordon RD.Author information Endocrine Hypertension Research Unit, University of Queensland, Greenslopes Hospital, Greenslopes, Queensland, Australia. gordon.rd@bigpond.comAbstractThe prevalence of "primary aldosteronism" (PAL) cannot be precisely determined at this time, given 1) lack of a universally accepted definition, and 2) normotensive as well as normokalemic phases in the evolutionary development of a disease eventually characterized by hypertension and hypokalemia. The exception is fully genetically characterised forms such as glucocorticoid-suppressible hyperaldosteronism, the true prevalence of which could be proven today by universal screening using a single blood sample, but this is neither practical nor appropriate. Controversy has arisen regarding the rareness, or otherwise, of PAL because of 1) rediscovery in the last 12 years of the normokalemic phase described by Conn, 2) application of widely available methods for measurement of aldosterone and renin to "screening", 3) variable quality of these methods, and of their application, and 4) lack of the necessary "diagnostic", in addition to "screening", tests in some studies. PAL is significantly more common than previously thought, and a very important potentially curable form of hypertension. Early diagnosis and specific treatment avoids morbidity. The current focus on increased detection is essential, and will help to resolve the question of prevalence.
- Arquivos brasileiros de endocrinologia e metabologia.Arq Bras Endocrinol Metabol.2004 Oct;48(5):666-73. Epub 2005 Mar 7.
- The prevalence of "primary aldosteronism" (PAL) cannot be precisely determined at this time, given 1) lack of a universally accepted definition, and 2) normotensive as well as normokalemic phases in the evolutionary development of a disease eventually characterized by hypertension and hypokalemia. T
- PMID 15761537
Japanese Journal
- 特発性アルドステロン症と糖質コルチコイド奏効性アルドステロン症
- Normotensive Glucocorticoid-Suppressible Hyperaldosteronism in Adult.
- MAEDA TSUYOSHI,ASHIE TAKESHI,KIKUIRI KUNIYASU,TAKAKURA MASAYUKI,HIKITA NOBUICHI,NAKAGAWA HIDEHISA,SHIMAMOTO KAZUAKI
- Endocrinologia Japonica 36(6), 817-825, 1989
- … Metabolic alkalosis, ACTH dependent hyperaldosteronism (18ng/dl) and over-response to synthetic ACTH were observed. … These results led us to suggest that this case might be normotensive glucocorticoid-suppressible hyperaldotseronism. …
- NAID 130000952712
Related Links
- Glucocorticoid-suppressible hyperaldosteronism information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues. ... Glucocorticoid-suppressible hyperaldosteronism: Related Topics ...
- Glucocorticoid-suppressible hyperaldosteronism: effects of crossover site and parental origin of chimaeric gene on phenotypic expression. Clin Sci (Lond). 1995 May; 88(5):563-70. [Clin Sci (Lond). 1995] Glucocorticoid-suppressible ...
★リンクテーブル★
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- 英
- glucocorticoid-suppressible hyperaldosteronism
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- 関
- repressible
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糖質コルチコイド
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高アルドステロン症