神経節細胞傍神経節腫
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/09/02 16:46:39」(JST)
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Gangliocytic paraganglioma |
Micrograph of a gangliocytic paraganglioma. H&E stain.
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Classification and external resources |
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A gangliocytic paraganglioma, abbreviated GP, is a rare tumour that is typically found in the duodenum and consists of three components: (1) ganglion cells, (2) epithelioid cells (paraganglioma-like) and, (3) spindle cells (schwannoma-like).[1]
Contents
- 1 Symptoms
- 2 Pathology
- 3 See also
- 4 Additional images
- 5 References
Symptoms
The most common presentation is gastrointestinal bleed (~45% of cases), followed by abdominal pain (~43% of cases) and anemia (~15% of cases).[2]
Pathology
GP consist of three components (1) ganglion cells, (2) epithelioid cells (neuroendocrine-like), and (3) spindle cells (schwannoma-like). The microscopic differential diagnosis includes poorly differentiated carcinoma, neuroendocrine tumour and paraganglioma.[1]
GPs may be sporadic or arise in the context neurofibromatosis type 1.
See also
Additional images
References
- ^ a b Wong, A.; Miller, AR.; Metter, J.; Thomas, CR. (Mar 2005). "Locally advanced duodenal gangliocytic paraganglioma treated with adjuvant radiation therapy: case report and review of the literature". World J Surg Oncol. 3 (1): 15. doi:10.1186/1477-7819-3-15. PMC 554089. PMID 15740625.
- ^ Okubo, Y.; Wakayama, M.; Nemoto, T.; Kitahara, K.; Nakayama, H.; Shibuya, K.; Yokose, T.; Yamada, M.; Shimodaira, K.; Sasai, Daisuke; Ishiwatari, Takao; Tsuchiya, Masaru; Hiruta, Nobuyuki (2011). "Literature survey on epidemiology and pathology of gangliocytic paraganglioma". BMC Cancer. 11: 187. doi:10.1186/1471-2407-11-187. PMC 3141762. PMID 21599949.
UpToDate Contents
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English Journal
- Primary cervical ganglioneuroblastoma.
- Manjaly JG1, Alexander VR2, Pepper CM2, Ifeacho SN2, Hewitt RJ2, Hartley BE2.
- International journal of pediatric otorhinolaryngology.Int J Pediatr Otorhinolaryngol.2015 Jul;79(7):1007-12. doi: 10.1016/j.ijporl.2015.04.012. Epub 2015 Apr 22.
- OBJECTIVES: Ganglioneuroblastomas represent a histological subgroup of the rare neuroblastic tumours with intermediate malignant potential arising from neural crest progenitor cells of sympathetic nerves. Diagnosis can often be difficult based on imaging alone. We describe 4 cases of children presen
- PMID 25921075
- Paraganglioma in pregnancy: A case series and review of the literature.
- Wing LA1, Conaglen JV1,2, Meyer-Rochow GY3,2, Elston MS1,2.
- The Journal of clinical endocrinology and metabolism.J Clin Endocrinol Metab.2015 Jun 17:jc20152122. [Epub ahead of print]
- CONTEXT: Pregnancies complicated by a phaeochromocytoma or paraganglioma are very rare, being estimated to occur in 0.007% of all pregnancies. Both the wellbeing of the mother and fetus need to be considered, and management can be challenging. The optimal management of women with a phaeochromocytoma
- PMID 26083822
- Gangliocytic Paraganglioma With Atypical Immunohistochemical Features Presenting as Extrahepatic Biliary Obstruction.
- Sharma S1, Gaspar BL1, Kumar P1, Yadav TD1, Vasishta RK2.
- International journal of surgical pathology.Int J Surg Pathol.2015 Jun 16. pii: 1066896915589969. [Epub ahead of print]
- Gangliocytic paraganglioma is a rare benign tumor of upper gastrointestinal tract that most commonly involves the second part of duodenum. The tumor is detected incidentally on imaging in most of the cases. However, presentation with extrahepatic biliary obstruction is extremely rare. We recently en
- PMID 26081293
Japanese Journal
- リンパ節転移を伴った十二指腸原発gangliocytic paragangliomaの1例
- 内視鏡的切除術を施行した十二指腸乳頭部gangliocytic paragangliomaの1例
- 急性膵炎を契機に発見された十二指腸gangliocytic paragangliomaの1例
Related Links
- 日消外会誌 29(12):2284∼. 2288,1996年. 十二指腸乳頭部 gangliocytic paragangliomaの 1例. 国府. 彰. 門根. はじめに. 十二十旨ル易字L頭部 gangliocytic paragangliomaは,一十. 二指腸にできるまれな腫瘍で1957年Dahlら 1)がgan‐ glioneuromaと ...
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