ガレクチン2
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English Journal
- Comparative lectinology: Delineating glycan-specificity profiles of the chicken galectins using neoglycoconjugates in a cell assay.
- Rapoport EM1, Matveeva VK1, Kaltner H2, André S2, Vokhmyanina OA1, Pazynina GV1, Severov VV1, Ryzhov IM1, Korchagina EY1, Belyanchikov IM1, Gabius HJ2, Bovin NV3.
- Glycobiology.Glycobiology.2015 Jul;25(7):726-34. doi: 10.1093/glycob/cwv012. Epub 2015 Feb 13.
- A major aspect of carbohydrate-dependent galectin functionality is their cross-linking capacity. Using a cell surface as biorelevant platform for galectin binding and a panel of 40 glycans as sensor part of a fluorescent polyacrylamide neoglycopolymer for profiling galectin reactivity, properties of
- PMID 25681326
- Galectin 2 (gal-2) expression is downregulated on protein and mRNA level in placentas of preeclamptic (PE) patients.
- Hutter S1, Martin N2, von Schönfeldt V3, Messner J1, Kuhn C1, Hofmann S1, Andergassen U1, Knabl J4, Jeschke U5.
- Placenta.Placenta.2015 Apr;36(4):438-45. doi: 10.1016/j.placenta.2015.01.198. Epub 2015 Feb 7.
- INTRODUCTION: Galectin 2 (gal-2) belongs to the proto type group and consists of two homologous carbohydrate recognition domains (CRDs) resulting in multiple sugar binding sites. The expression of gal-2 has been shown to be involved in processes of angiogenesis and inflammation but was not analyzed
- PMID 25707742
- S-nitrosylation of mouse galectin-2 prevents oxidative inactivation by hydrogen peroxide.
- Tamura M1, Saito M1, Yamamoto K1, Takeuchi T1, Ohtake K2, Tateno H3, Hirabayashi J3, Kobayashi J2, Arata Y4.
- Biochemical and biophysical research communications.Biochem Biophys Res Commun.2015 Feb 20;457(4):712-7. doi: 10.1016/j.bbrc.2015.01.055. Epub 2015 Jan 22.
- Galectins are a group of animal lectins characterized by their specificity for β-galactosides. Galectin-2 (Gal-2) is predominantly expressed in the gastrointestinal tract. A proteomic analysis identified Gal-2 as a protein that was S-nitrosylated when mouse gastric mucosal lysates were reacted with
- PMID 25619132
Japanese Journal
- Engineering of a 3'-sulpho-Galβ1-4GlcNAc-specific probe by a single amino acid substitution of a fungal galectin
- Hu Dan,Huang Hang,Tateno Hiroaki [他]
- The journal of biochemistry 157(4), 197-200, 2015-04
- NAID 40020428719
- TIM-3分子の基礎と臨床応用 (特集 免疫チェックポイントの基礎と臨床)
- Prognostic Value of Plasma Galectin-3 Levels in Patients With Coronary Heart Disease and Chronic Heart Failure
- , , , , , , , , , ,
- International Heart Journal 56(3), 314-318, 2015
- … In this study, we evaluated the prognostic value of plasma galectin-3 levels in patients with coronary heart disease (CHD) and chronic heart failure (HF) and selected 261 CHD patients who were consecutively admitted to our hospital. … Galectin-3 and B-type natriuretic peptide (BNP) levels were determined and the primary endpoint was the composite of all-cause mortality and rehospitalization with 12-month follow-up. …
- NAID 130005070018
Related Links
- 15 Sep 2004 ... Galectin-2 is structurally closely related to galectin-1, but has a distinct expression profile primarily confined to the gastrointestinal tract. Prominent differences in the proximal promoter regions between galectins-2 and -1 ...
- Results 1 - 7 of 7 ... The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) ...
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- S-type lectin