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infectious disease characterized by inflammation of the meninges (the tissues that surround the brain or spinal cord) usually caused by a bacterial infection; symptoms include headache and stiff neck and fever and nausea
of or relating to fungi (同)fungous

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脳膜炎

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/11/06 10:51:49」(JST)

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Fungal meningitis refers to meningitis caused by a fungal infection.

One form of fungal meningitis is cryptococcal meningitis.^[1] Patients treated for cancer or chronic illnesses where treatments and/or the disease itself compromise the patient's immune system are particularly vulnerable. Most common in AIDS patients, cryptococcal fungal meningitis cases have increased globally during the past decade. National health data estimates the incidence to be approximately 1,500 cases annually in the U.S.^[2]^[3]^[4]

New England Compounding Center meningitis outbreak

As of November 5, 2012, the CDC reported that 409 patients had laboratory-confirmed fungal meningitis caused by injections with contaminated medication.There had been 30 fatalities. A black mold, Exserohilum rostratum, was found in 45 of these cases. Aspergillus fumigatus was found in one case, and a Cladosporium species was found in one case.^[5] Aspergillus has been very rarely associated with meningitis^[6] while cases caused explicitly by Exserohilum in otherwise healthy individuals have not been previously reported.^[7]

References

^ Safdieh JE, Mead PA, Sepkowitz KA, Kiehn TE, Abrey LE (March 2008). "Bacterial and fungal meningitis in patients with cancer". Neurology. 70 (12): 943–7. doi:10.1212/01.wnl.0000305960.85546.5f. PMID 18347316.
^ Jaiswal SP, Hemwani N, Sharma N, Athale S, Chitnis DS (July 2002). "Prevalence of fungal meningitis among HIV positive & negative subjects in Indore (MP state)". Indian J Med Sci. 56 (7): 325–9. PMID 12645168.
^ Slavoski LA, Tunkel AR (April 1995). "Therapy of fungal meningitis". Clin Neuropharmacol. 18 (2): 95–112. doi:10.1097/00002826-199504000-00001. PMID 8635178.
^ Long Island Man and Grandfather Beats Fungal Meningitis
^ "Current Situation:CDC Responds to Multistate Fungal Meningitis Outbreak". CDC. 18 October 2012. Retrieved 21 October 2012.
^ Badiee P, Alborzi A (2011). “Assessment of a real-time PCR method to detect human non-cryptococcal fungal meningitis”. Arch Iran Med.14(6):381-4. PMID 22039841
^ A Adler, I Yaniv, Z Samra, J Yacobovich, S Fisher, G Avrahami, I Levy (2006). “Exserohilum: an emerging human pathogen.” Eur J Clin Microbiol Infect Dis. 2006 Mar 2;: 16511679

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1. 米国における真菌による中枢神経系感染症および骨関節感染症のアウトブレイク：疫学、臨床症状および診断 outbreak of fungal central nervous system and osteoarticular infections in the united states epidemiology clinical manifestations and diagnosis
2. 米国における真菌による中枢神経系感染症および骨関節感染症のアウトブレイク：治療 outbreak of fungal central nervous system and osteoarticular infections in the united states treatment
3. HIV血清陰性患者におけるクリプトコッカス-ネオフォルマン髄膜脳炎および播種性感染症の治療 treatment of cryptococcus neoformans meningoencephalitis and disseminated infection in hiv seronegative patients
4. 中枢神経系のカンジダ感染症 candida infections of the central nervous system
5. コクシジオイデス性髄膜炎 coccidioidal meningitis

English Journal

Cerebrospinal fluid cytology in nonmalignant aseptic meningeal disorders.

Martínez-Girón R1, Pantanowitz L2.
Diagnostic cytopathology.Diagn Cytopathol.2017 Nov;45(11):1020-1029. doi: 10.1002/dc.23797. Epub 2017 Aug 16.
PMID 28816034

First report of urease activity in the novel systemic fungal pathogen Emergomyces africanus: a comparison with the neurotrope Cryptococcus neoformans.

Lerm B1, Kenyon C2,3, Schwartz IS4,5, Kroukamp H1, de Witt R1, Govender NP3,6, de Hoog GS7, Botha A1.
FEMS yeast research.FEMS Yeast Res.2017 Nov 1;17(7). doi: 10.1093/femsyr/fox069.
PMID 28934415

Cryptococcosis in patients with diabetes mellitus II in mainland China: 1993-2015.

Li Y1,2, Fang W1,2, Jiang W1,2, Hagen F3, Liu J1,2, Zhang L1,2, Hong N1,2, Zhu Y1,2, Xu X1,2, Lei X4, Deng D5, Xu J6, Liao W1,2, Boekhout T2,7,8, Chen M1,2,8, Pan W1,2.
Mycoses.Mycoses.2017 Nov;60(11):706-713. doi: 10.1111/myc.12645. Epub 2017 Aug 30.
PMID 28857298

Japanese Journal

Successful Treatment of Serial Opportunistic Infections Including Disseminated Nocardiosis and Cryptococcal Meningitis in a Patient with ANCA-associated Vasculitis

Iwazu Kana,Iwazu Yoshitaka,Takeda Shin-ichi,Akimoto Tetsu,Yumura Wako,Takahashi Hideaki,Ito Chiharu,Kanai Kuniyuki,Taniguchi Nobuyuki,Hirai Yoshikazu,Kusano Eiji
Internal Medicine 51(21), 3051-3056, 2012
… We herein present a case of serial opportunistic infections that included disseminated nocardiosis and cryptococcal meningitis in a 67-year-old man who was diagnosed with ANCA-associated vasculitis and treated with corticosteroids. … Anti-fungal treatment resulted in the remission of cryptococcal meningitis. …
NAID 130002061954

Lymphocytic Hypophysitis Accompanied by Aseptic Meningitis Mimics Subacute Meningoencephalitis

Suzuki Keisuke,Izawa Naoki,Nakamura Toshiki,Hashimoto Kenichi,Ouchi Keita,Sakuta Hideki,Asakawa Yohei,Numao Ayaka,Hirata Koichi
Internal Medicine 50(18), 2025-2030, 2011
… The tests for tuberculous, fungal and carcinomatous meningitis and herpetic meningoencephalitis were negative. … A diagnosis of lymphocytic hypophysitis with aseptic meningitis was made after the exclusion of secondary hypophysitis. … Lymphocytic hypophysitis with aseptic meningitis can mimic subacute meningoencephalitis. …
NAID 130000969317

肺クリプトコックス症に対する外科切除例の検討

竹中賢,花桐武志,岡壮一,馬場哲郎,安田学,小野憲司,浦本秀隆,宗知子,竹之山光広,山田壮亮,安元公正
産業医科大学雑誌 32(3), 237-243, 2010-09-01
肺クリプトコックス症は,Cryptococcus neoformansが吸入されることによって生じる肺真菌症であり,免疫能が低下した易感染性宿主に発生する日和見感染症とされるが,健常人における罹患も知られており,近年では健康診断および他疾患精査中などで偶然発見されることが増加している.今回,外科治療を施行した肺クリプトコックス症8例について検討した.年齢は49歳から85歳,男性4例,女性4例であっ …
NAID 110007700769

「真菌性髄膜炎」

Fungal meningitis
	Fungus (black) in brain tissue
Classification and external resources
MeSH	D016921
	[edit on Wikidata]

　　[★]

英: fungal meningitis
関: 亜急性髄膜炎、髄膜炎

「fungal」

　　[★]

adj.

真菌の

関: fungi、fungus、myco

[pmid18347316-1] Safdieh JE, Mead PA, Sepkowitz KA, Kiehn TE, Abrey LE (March 2008). "Bacterial and fungal meningitis in patients with cancer". Neurology. 70 (12): 943–7. doi:10.1212/01.wnl.0000305960.85546.5f. PMID 18347316.

[pmid12645168-2] Jaiswal SP, Hemwani N, Sharma N, Athale S, Chitnis DS (July 2002). "Prevalence of fungal meningitis among HIV positive & negative subjects in Indore (MP state)". Indian J Med Sci. 56 (7): 325–9. PMID 12645168.

[pmid8635178-3] Slavoski LA, Tunkel AR (April 1995). "Therapy of fungal meningitis". Clin Neuropharmacol. 18 (2): 95–112. doi:10.1097/00002826-199504000-00001. PMID 8635178.

[4] Long Island Man and Grandfather Beats Fungal Meningitis

[5] "Current Situation:CDC Responds to Multistate Fungal Meningitis Outbreak". CDC. 18 October 2012. Retrieved 21 October 2012.

[6] Badiee P, Alborzi A (2011). “Assessment of a real-time PCR method to detect human non-cryptococcal fungal meningitis”. Arch Iran Med.14(6):381-4. PMID 22039841

[7] A Adler, I Yaniv, Z Samra, J Yacobovich, S Fisher, G Avrahami, I Levy (2006). “Exserohilum: an emerging human pathogen.” Eur J Clin Microbiol Infect Dis. 2006 Mar 2;: 16511679

v t e Meningitis and other diseases of meninges (G00–G03, 320–322)
Meningitis	Arachnoiditis Bacterial Tuberculous Haemophilus Pneumococcal Viral Herpesviral Fungal Cryptococcal Aseptic Drug-induced
Other	Meningoencephalitis

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案内

fungal meningitis