UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. メトトレキサートを使用した関節リウマチ治療 use of methotrexate in the treatment of rheumatoid arthritis
2. 高用量メトトレキサートの治療使用および毒性 therapeutic use and toxicity of high dose methotrexate

English Journal

Neurological improvement following intravenous high-dose folinic acid for cerebral folate transporter deficiency caused by FOLR-1 mutation.

Delmelle F1, Thöny B2, Clapuyt P1, Blau N3, Nassogne MC4.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.Eur J Paediatr Neurol.2016 Jun 13. pii: S1090-3798(16)30078-2. doi: 10.1016/j.ejpn.2016.05.021. [Epub ahead of print]
BACKGROUND: Cerebral folate transporter deficiency caused by FOLR-1 mutations has been described in 2009. This condition is characterized by a 5MTHF level <5 nmol/l in the CSF, along with regression of acquisition in the second year of life, ataxia, and refractory myoclonic epilepsy. Oral or int
PMID 27328863

Protective effect of mesoporous silica particles on encapsulated folates.

Ruiz-Rico M1, Daubenschüz H2, Pérez-Esteve É2, Marcos MD3, Amorós P4, Martínez-Máñez R3, Barat JM2.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.Eur J Pharm Biopharm.2016 May 25. pii: S0939-6411(16)30181-3. doi: 10.1016/j.ejpb.2016.05.016. [Epub ahead of print]
Mesoporous silica particles (MSPs) are considered suitable supports to design gated materials for the encapsulation of bioactive molecules. Folates are essential micronutrients which are sensitive to external agents that provoke nutritional deficiencies. Folates encapsulation in MSPs to prevent degr
PMID 27235728

Enzymes required for the biosynthesis of N-formylated sugars.

Holden HM1, Thoden JB2, Gilbert M3.
Current opinion in structural biology.Curr Opin Struct Biol.2016 May 19;41:1-9. doi: 10.1016/j.sbi.2016.04.003. [Epub ahead of print]
The N-formyltransferases, also known as transformylases, play key roles in de novo purine biosynthesis where they catalyze the transfer of formyl groups to primary amine acceptors. These enzymes require N10-formyltetrahydrofolate for activity. Due to their biological importance they have been extens
PMID 27209114

Japanese Journal

Changes in the Acetogenic Population in a Mesophilic Anaerobic Digester in Response to Increasing Ammonia Concentration

Microbes and environments 26(4), 347-353, 2011-12-01
NAID 10029978254

Changes in the Acetogenic Population in a Mesophilic Anaerobic Digester in Response to Increasing Ammonia Concentration

Microbes and Environments 26(4), 347-353, 2011
NAID 130001024018

Identification of differentially expressed genes in Sulfobacillus sp. TPY grown on either elemental sulphur or Fe2+

The Journal of General and Applied Microbiology 56(5), 389-397, 2010
NAID 130004719793

Related Pictures

Tetrahydrofolate Reductase Dihydrofolate 10 -formyltetrahydrofolate donor n 10 formyl tetrahydrofolate by a Acids; N(10)-Formyltetrahydrofolate 10-Formyltetrahydrofolate - Wikipedia, the of the 10-formyltetrahydrofolate molecule methylene tetrahydrofolate