Nanoparticles in Porous Microparticles Prepared by Supercritical Infusion and Pressure Quench Technology for Sustained Delivery of Bevacizumab.
Yandrapu SK, Upadhyay AK, Petrash JM, Kompella UB.SourceNanomedicine and Drug Delivery Laboratory, Department of Pharmaceutical Sciences, ‡Department of Ophthlamology, and §Department of Bioengineering University of Colorado Anschutz Medical Campus , Aurora, Colorado 80045, United States.
Molecular pharmaceutics.Mol Pharm.2013 Nov 12. [Epub ahead of print]
Nanoparticles in porous microparticles (NPinPMP), a novel delivery system for sustained delivery of protein drugs, was developed using supercritical infusion and pressure quench technology, which does not expose proteins to organic solvents or sonication. The delivery system design is based on the a
A sensitive and selective sensor for oxidized glutathione (GSSG) detection based on the recovered fluorescence of naphthalimide-DPA (NDPA)-Fe₃O₄@SiO₂-Cu(II) system is reported. NDPA-Fe3Fe₃O₄@SiO₂ was characterized by X-ray power diffraction (XRD), transmission electron microscopy (TEM),
Potential of nonoral α-lipoic acid aqueous formulations to reduce ocular microvascular complications in a streptozotocin-induced diabetic rat model.
Chen CL, Cheng WS, Chen JL, Chiang CH.Source1 Far Eastern Memorial Hospital , New Taipei City, Taiwan .
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.J Ocul Pharmacol Ther.2013 Oct;29(8):738-45. doi: 10.1089/jop.2012.0147. Epub 2013 Jul 13.
PURPOSE: α-Lipoic acid (LA) aqueous formulations were studied for nonoral administration, including intravitreal and intraperitoneal preparations and topical eyedrops. The potential retinoprotective effects of these LA preparations were also evaluated in streptozotocin (STZ)-induced diabetic rats f
A novel fluorophotometric method was established for the determination of serotonin on the heating in propylene glycol. In the determination of serotonin, the calibration curve exhibited linearity …
fluorophotometry [floor″o-fo-tom´ĕ-tre] fluorometry. vitreous fluorophotometry the measurement of light given off by intravenously injected fluorescein that has leaked through the retinal vessels into the vitreous; done to detect the ...
fluorophotometry fluor·o·pho·tom·e·try (flur'ō-fō-tŏm'ĭ-trē, flôr'-) n. Measurement of the light emitted by a fluorescent substance, especially that emitted from the interior of the eye after intravenous injection of fluorescein to test the ...