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any of a class of organic compounds having a carbonyl group linked to a carbon atom in each of two hydrocarbon radicals

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Caspase-3 is Involved in Aluminum-Induced Impairment of Long-Term Potentiation in Rats Through the Akt/GSK-3β Pathway.

Zhang H1, Yang X1, Qin X1, Niu Q2.
Neurotoxicity research.Neurotox Res.2016 Jan 19. [Epub ahead of print]
A number of studies have indicated that aluminum (Al) exposure can impair learning and memory function. The ability of Al to inhibit hippocampal long-term potentiation (LTP) suggests the possibility of Al impairing synaptic plasticity. LTP is dependent on the externalization of alpha-amino-3-hydroxy
PMID 26787483

Features of cell death, mitochondrial activation and caspase dependence of rabbit anti-T-lymphocyte globulin signaling in lymphoblastic Jurkat cells are distinct from classical apoptosis signaling of CD95.

Ziegler C1,2,3, Finke J2, Grüllich C1,2.
Leukemia & lymphoma.Leuk Lymphoma.2016 Jan;57(1):177-82. doi: 10.3109/10428194.2015.1044449. Epub 2015 May 25.
Rabbit anti-T-lymphocyte-globulin (ATG) is used for immunosuppression in organ and stem cell transplantation. The aim of this study was to investigate ATG-induced cell death compared to CD95-signaling of apoptosis. We measured features of cell death at the cell membrane, mitochondria, nuclei and cas
PMID 25927246

Benzophenone 1 induced photogenotoxicity and apoptosis via release of cytochrome c and Smac/DIABLO at environmental UV radiation.

Amar SK1, Goyal S1, Dubey D2, Srivastav AK2, Chopra D2, Singh J2, Shankar J3, Chaturvedi RK4, Ray RS5.
Toxicology letters.Toxicol Lett.2015 Dec 15;239(3):182-93. doi: 10.1016/j.toxlet.2015.09.024. Epub 2015 Oct 9.
Solar UV radiation is main factor of photocarcinogenesis, photoageing, and phototoxicity; thus, protection from UV radiation is major concern. Sunscreens containing UV filters are suggested as sun safe practices, but safety of UV filters remains in controversies. Benzophenone-1 (BP1) is commonly use
PMID 26440554

The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis

Sulphur Antioxidants Inhibit Oxidative Stress Induced Retinal Ganglion Cell Death by Scavenging Reactive Oxygen Species but Influence Nuclear Factor (Erythroid-Derived 2)-Like 2 Signalling Pathway Differently