濾過率
WordNet
- a component of a mixture that has been separated by a fractional process
- the quotient of two rational numbers
- a small part or item forming a piece of a whole
- the process whereby fluids pass through a filter or a filtering medium
- the act of changing a fluid by passing it through a filter
PrepTutorEJDIC
- 『破片』,断片;(…の)一部,わずか《+『of』+『名』》 / 『分数』
- ろ過,ろ過作用
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/02/15 17:13:59」(JST)
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Parameter |
Value |
renal blood flow |
RBF=1000 ml/min |
hematocrit |
HCT=40% |
renal plasma flow |
RPF=600 ml/min |
filtration fraction |
FF=20% |
glomerular filtration rate |
GFR=120 ml/min |
urine flow rate |
V=1 mL/min |
Sodium |
Inulin |
Creatinine |
PAH |
SNa=150 mEq/L |
SIn=1 mg/mL |
SCr=0.01 mg/ml |
SPAH= |
UNa=710 mEq/L |
UIn=150 mg/mL |
UCr=1.25 mg/mL |
UPAH= |
CNa=5 mL/min |
CIn=150 ml/min |
CCr=125 mL/min |
CPAH=420 ml/min |
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ER=90% |
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ERPF=540 ml/min |
In renal physiology, the filtration fraction is the ratio of the glomerular filtration rate (GFR) to the renal plasma flow (RPF).
Filtration Fraction, FF = GFR/RPF
The filtration fraction, therefore, represents the proportion of the fluid reaching the kidneys which passes into the renal tubules. It is normally about 20%.
The GFR on its own is the most common and important measure of renal function. However, in a condition such as renal artery stenosis, the blood flow to the kidneys is reduced. The filtration must therefore be increased in order to perform the normal tasks of the kidney in balancing fluid and electrolytes in the body. This would be reflected by a high filtration fraction, showing that the kidneys have to do more work with the fluid they are receiving. Diuretics such as loops and thiazides decrease the filtration fraction.
Catecholamines (Norepinephrine and Epinephrine) increase the filtration fraction by vasoconstriction of afferent and efferent arterioles, which is possibly activated by alpha 1 adrenergic receptors.
Severe haemorrhage will also result in an increased filtration fraction.
References
Urinary system physiology: renal physiology and acid-base physiology
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Filtration |
- Renal blood flow
- Ultrafiltration
- Countercurrent exchange
- Filtration fraction
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Hormones affecting
filtration |
- Antidiuretic hormone (ADH)
- Aldosterone
- Atrial natriuretic peptide
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Secretion /
clearance |
- Pharmacokinetics
- Clearance of medications
- Urine flow rate
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Reabsorption |
- Solvent drag
- Na+
- Cl−
- urea
- glucose
- oligopeptides
- protein
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Endocrine |
- Renin
- Erythropoietin (EPO)
- Calcitriol (Active vitamin D)
- Prostaglandins
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Assessing
renal function/
measures of dialysis |
- Glomerular filtration rate
- Creatinine clearance
- Renal clearance ratio
- Urea reduction ratio
- Kt/V
- Standardized Kt/V
- Hemodialysis product
- PAH clearance (Effective renal plasma flow
- Extraction ratio)
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|
Acid-base
physiology |
- Fluid balance
- Darrow Yannet diagram
Body water: Intracellular fluid/Cytosol
- Extracellular fluid
- (Interstitial fluid
- Plasma
- Transcellular fluid)
- Base excess
- Davenport diagram
- Anion gap
- Arterial blood gas
- Winter's formula
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Buffering/
compensation |
- Bicarbonate buffering system
- Respiratory compensation
- Renal compensation
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Other |
- Fractional sodium excretion
- BUN-to-creatinine ratio
- Tubuloglomerular feedback
- Natriuresis
- Urine
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Index of the urinary system
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Description |
- Anatomy
- Physiology
- Development
- Cells
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Disease |
- Electrolyte and acid-base
- Congenital
- Neoplasms and cancer
- Other
- Symptoms and signs
- Urine tests
- Blood tests
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Treatment |
- Procedures
- Drugs
- Intravenous fluids
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UpToDate Contents
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English Journal
- Antioxidant activities and functional properties of protein and peptide fractions isolated from salted herring brine.
- Taheri A, Sabeena Farvin KH, Jacobsen C, Baron CP.SourceDepartment of Seafood Sciences, Faculty of Marine Sciences, Chabahar Maritime University, P.O. Box 99717-65499, Chabahar, Iran.
- Food chemistry.Food Chem.2014 Jan 1;142:318-26. doi: 10.1016/j.foodchem.2013.06.113. Epub 2013 Jul 4.
- In the present study proteins isolated from herring brine, which is a by-product of marinated herring production were evaluated for their functional properties and antioxidant activity. Herring brine was collected from the local herring industry and proteins were precipitated by adjusting the pH to
- PMID 24001848
- Novel UMOD mutations in familial juvenile hyperuricemic nephropathy lead to abnormal uromodulin intracellular trafficking.
- Liu M, Chen Y, Liang Y, Liu Y, Wang S, Hou P, Zhang H, Zhao M.SourceRenal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of Chronic Kidney Disease Prevention and Treatment, Ministry of Education, Beijing 100034, China.
- Gene.Gene.2013 Dec 1;531(2):363-9. doi: 10.1016/j.gene.2013.08.041. Epub 2013 Aug 27.
- BACKGROUND: Familial juvenile hyperuricemic nephropathy (FJHN) is an autosomal dominant disorder characterized by hyperuricemia and progressive chronic kidney disease. Uromodulin gene (UMOD) mutations, leading to abnormalities of uromodulin intracellular trafficking contribute to the progress of the
- PMID 23988501
- Glucogalactan: a polysaccharide isolated from the cell-wall of Verticillium lecanii.
- Corradi da Silva ML, Exposti DT, Vasconcelos AF, Alexandre SM, Silveira JL, Ducatti DR.SourceDepartamento de Física, Química e Biologia, Faculdade de Ciências e Tecnologia, Universidade Estadual Paulista, CEP 19060-900, Presidente Prudente, São Paulo, Brazil. Electronic address: corradi@fct.unesp.br.
- Carbohydrate polymers.Carbohydr Polym.2013 Nov 6;98(2):1353-9. doi: 10.1016/j.carbpol.2013.07.075. Epub 2013 Aug 3.
- A water-soluble polysaccharide was extracted with alkali from the cell wall of Verticillium lecanii (also called Lecanicillium lecanii). After freezing and thawing, the water-soluble fraction was purified by gel filtration chromatography on Sepharose CL-6B and eluted as one peak by HPSEC/RID. Monosa
- PMID 24053813
Japanese Journal
- Effects of Mixing Ratio of Binary Fine Particles on the Packing Density and Filtration Characteristics
- Combined Global Longitudinal Strain and Intraventricular Mechanical Dyssynchrony Predicts Long-Term Outcome in Patients With Systolic Heart Failure
- Prognostic Impact of New-Onset Atrial Fibrillation in Patients With Chronic Heart Failure – A Report From the CHART-2 Study –
Related Links
- fil·tra·tion frac·tion (FF), the fraction of the plasma entering the kidney that filters into the lumen of the renal tubules, determined by dividing the glomerular filtration rate by the renal plasma flow; normally, it is around 0.17. filtration ...
- filtration fraction n. The portion of blood plasma that enters the kidney and filters through the renal glomerular membranes.
★リンクテーブル★
[★]
- 英
- filtration fraction, FF
- 関
- 糸球体濾過値、腎血漿流量
[★]
濾過率 filtration fraction
[★]
- (数学)分数、(整数以外の)有理数。端数
- はした。断片、破片、小部分。ほんの少し
- (化学)留分。(化学)画分
- 分割
- 関
- fractional、fractionate、fractionation、percentage、proportion、rate、ratio
[★]
- 関
- filter、filtrate、leach