Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.Nephrol Dial Transplant.2015 Jul 13. pii: gfv277. [Epub ahead of print]
BACKGROUND: Administration of ferric pyrophosphate citrate (FPC, Triferic™) via hemodialysate may allow replacement of ongoing uremic and hemodialysis-related iron losses. FPC donates iron directly to transferrin, bypassing the reticuloendothelial system and avoiding iron sequestration.METHODS: Tw
Ferric pyrophosphate citrate administered via dialysate reduces erythropoiesis-stimulating agent use and maintains hemoglobin in hemodialysis patients.
Ferric pyrophosphate citrate (FPC) is a water-soluble iron salt administered via dialysate to supply iron directly to transferrin. The PRIME study tested whether treatment with FPC could reduce prescribed erythropoiesis-stimulating agent (ESA) use and maintain hemoglobin in hemodialysis patients. Th
Iron deficiency anemia is one of the major nutritional deficiency disorders. Iron deficiency anemia occurs due to decreased absorption of iron from diet, chronic blood loss and other associated diseases. The importance of iron and deleterious effects of iron deficiency anemia are discussed briefly i
Journal of Nutritional Science and Vitaminology 56(3), 191-197, 2010
… The volunteers were randomly assigned into four groups, i.e., Group A: received 15 mg Fe as ferricpyrophosphate; … Group B: received 15 mg Fe as ferricpyrophosphate and 1.25 g DFAIII; …
Ferric Pyrophosphate. Fe4(P2O7)3. Mol. Wt. 745.22 iron(Ⅲ) diphosphate. Content Ferric Pyrophosphate, when ignited, contains not less than 95.0% of ferric pyrophosphate (Fe4(P2O7)3). Description Ferric Pyrophosphate occurs as a yellow ...
The iron bioavailability from ferric pyrophosphate was investigated by hemoglobin repletion assay. Three iron sources were prepared from the aqueous suspension of ferric pyrophosphate: mixed with skim milk and dehydrated (FPl), directly ...