ferredoxin-nitrite reductase

• フェレドキシン亜硝酸還元酵素

WordNet

1. an enzyme that catalyses the biochemical reduction of some specified substance
2. the radical -NO2 or any compound containing it (such as a salt or ester of nitrous acid)

PrepTutorEJDIC

1. 亜硝酸塩

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/02/03 20:50:42」(JST)

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ferredoxin—nitrite reductase
Identifiers
EC number	1.7.7.1
CAS number	37256-44-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a ferredoxin—nitrite reductase (EC 1.7.7.1) is an enzyme that catalyzes the chemical reaction

NH₃ + 2 H₂O + 6 oxidized ferredoxin nitrite + 6 reduced ferredoxin + 7 H⁺

The 3 substrates of this enzyme are NH₃, H₂O, and oxidized ferredoxin, whereas its 3 products are nitrite, reduced ferredoxin, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is ammonia:ferredoxin oxidoreductase. This enzyme participates in nitrogen metabolism and nitrogen assimilation. It has 3 cofactors: iron, Siroheme, and Iron-sulfur.

This enzyme can use many different isoforms of ferredoxin. In photosynthesizing tissues, it uses ferredoxin that is reduced by PSI and in the root it uses a form of ferredoxin (FdIII) that has a less negetive midpoint potential and can be reduced easily by NADPH.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1ZJ8, 1ZJ9, and 2AKJ.

References

• Joy KW, Hageman RH (1966). "The purification and properties of nitrite reductase from higher plants, and its dependence on ferredoxin". Biochem. J. 100 (1): 263–73. PMC 1265119. PMID 4381617. 
• Ramirez JM, Del Campo FF, Paneque A, Losada M (1966). "Ferredoxin-nitrite reductase from spinach". Biochim. Biophys. Acta. 118 (1): 58–71. PMID 5954064. 
• Zumft WG, Paneque A, Aparicio PJ, Losada M (1969). "Mechanism of nitrate reduction in Chlorella". Biochem. Biophys. Res. Commun. 36 (6): 980–6. doi:10.1016/0006-291X(69)90300-3. PMID 4390523. 

UpToDate Contents

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English Journal

• Ectopic expression of a cyanobacterial flavodoxin in creeping bentgrass impacts plant development and confers broad abiotic stress tolerance.

• Li Z1,2, Yuan S2, Jia H2,3, Gao F2,4, Zhou M2, Yuan N2, Wu P2, Hu Q2, Sun D5, Luo H6.
• Plant biotechnology journal.Plant Biotechnol J.2016 Sep 16. doi: 10.1111/pbi.12638. [Epub ahead of print]
• Flavodoxin (Fld) plays a pivotal role in photosynthetic microorganisms as an alternative electron carrier flavoprotein under adverse environmental conditions. Cyanobacterial Fld has been demonstrated to be able to substitute ferredoxin of higher plants in most electron transfer processes under stres
• PMID 27638479

• Arabidopsis Root-Type Ferredoxin:NADP(H) Oxidoreductase 2 Is Involved in Detoxification of Nitrite in Roots.

• Hachiya T1, Ueda N2, Kitagawa M3, Hanke G4, Suzuki A5, Hase T6, Sakakibara H7.
• Plant & cell physiology.Plant Cell Physiol.2016 Sep 11. pii: pcw158. [Epub ahead of print]
• Ferredoxin : NADP(H) oxidoreductase (FNR) plays a key role in redox metabolism in plastids. Whereas leaf FNR (LFNR) is required for photosynthesis, root FNR (RFNR) is believed to provide electrons to ferredoxin (Fd)-dependent enzymes, including nitrite reductase (NiR) and Fd-glutamine-oxoglutarate a
• PMID 27615794

• Remembering David B. Knaff (1941-2016).

• Malkin R1.
• Photosynthesis research.Photosynth Res.2016 Jul;129(1):1-12. doi: 10.1007/s11120-016-0265-7. Epub 2016 Apr 29.
• David Knaff began his scientific career in the Department of Cell Physiology at the University of California, Berkeley. At Berkeley, he worked on chloroplast electron carriers such as the cytochromes and plastocyanin and applied redox potentiometry to characterize these carriers in situ. He moved to
• PMID 27130553

Japanese Journal

• Cloning and Nucleotide Sequence of a Leaf Ferredoxin-Nitrite Reductase cDNA of Rice

• Bioscience, biotechnology, and biochemistry 59(11), 2183-2185, 1995-11-23
• NAID 110002677866

• Primary Structure and Transcriptional Regulation of the Gene for Nitrite Reductase from the Cyanobacterium Synechococcus PCC 7942 :

• Plant and cell physiology 34(8), 1311-1320, 1993
• NAID 110003720398

• 藍藻Spirulina platensisのフェレドキシン依存性亜硝酸還元酵素〔英文〕

• 藻類 39(4), p337-345, 1991-12
• NAID 40002239208

Related Links

• NIR1 - Ferredoxin--nitrite reductase, chloroplastic precursor ...

Catalyzes the six-electron reduction of nitrite to ammonium. ... « Hide 10 20 30 40 50 MTSFSLTFTS PLLPSSSTKP KRSVLVAAAQ TTAPAESTAS VDADRLEPRV 60 70 80 90 100 ELKDGFFILK EKFRKGINPQ EKVKIEREPM KLFMENGIEE LAKKSMEELD ...

• Ferredoxin-nitrite reductase from spinach

FERREDOXIN-NITRITE REDUCTASE FROM SPINACH J. M. RAMIREZ, F. F. DEL CAMPO, A. PANEQUE AND M. LOSADA Seccion de Fisiologla Celular, Instituto de Biologla Celular, C.S.I.C., Madrid (Spain) (Received July 9th ...

Related Pictures

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★リンクテーブル★

リンク元	「フェレドキシン亜硝酸還元酵素」
関連記事	「reductase」「nitrite reductase」「ferredoxin」

「フェレドキシン亜硝酸還元酵素」

　　[★]

英

ferredoxin-nitrite reductase

「reductase」

　　[★]

• n.

(酵素)還元酵素、レダクターゼ、リダクターゼ

関

dehydrogenase、oxidase、oxidoreductase、reducing enzyme

　

「nitrite reductase」

　　[★]

亜硝酸還元酵素、亜硝酸レダクターゼ

「ferredoxin」

　　[★]

フェレドキシン

関

Fd