English Journal

SKF83959 suppresses excitatory synaptic transmission in rat hippocampus via a dopamine receptor-independent mechanism.

Chu HY, Wu Q, Zhou S, Cao X, Zhang A, Jin GZ, Hu GY, Zhen X.SourceState Key Laboratory of Drug Research and Department of Pharmacology II, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Journal of neuroscience research.J Neurosci Res.2011 Aug;89(8):1259-66. doi: 10.1002/jnr.22653. Epub 2011 May 2.
Dopamine (DA) profoundly modulates excitatory synaptic transmission and synaptic plasticity in the brain. In the present study the effects of SKF83959, the selective agonist of phosphatidylinositol (PI)-linked D(1) -like receptor, on the excitatory synaptic transmission were investigated in rat hipp
PMID 21538463

MPTP-meditated hippocampal dopamine deprivation modulates synaptic transmission and activity-dependent synaptic plasticity.

Zhu G, Chen Y, Huang Y, Li Q, Behnisch T.SourceInstitutes of Brain Science, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, PR China; State Key Laboratory of Medical Neurobiology, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, PR China.
Toxicology and applied pharmacology.Toxicol Appl Pharmacol.2011 Aug 1;254(3):332-41. Epub 2011 May 14.
Parkinson's disease (PD)-like symptoms including learning deficits are inducible by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Therefore, it is possible that MPTP may disturb hippocampal memory processing by modulation of dopamine (DA)- and activity-dependent synaptic plasticity. We demons
PMID 21605582

Japanese Journal

Yang Jung-Hwa,Han Sang-Jun,Ryu Jong Hoon,Jang Il-Sung,Kim Dong-Hyun
Biological & Pharmaceutical Bulletin 32(10), 1710-1715, 2009
… It recovered field excitatory post synaptic potential (fEPSP) amplitude potentiation to 152.3±8.7% of the control (p<0.05). …
NAID 130000116931

中島龍一,中村健,宮川博義,工藤佳久
日本薬理学雑誌 : FOLIA PHARMACOLOGICA JAPONICA 123(6), 413-419, 2004-06-01
浮腫は，傷害後に起こる様々な細胞内分子反応経路の集約点である．浮腫を観察し，定量化することで，障害の程度を把握することができれば，様々な保護薬の作用を簡便に評価することができる．我々は，急性スライス標本における細胞の浮腫を定量化することが出来る新しい測定系を開発したので本稿で紹介する．この測定系は，赤外線微分干渉顕微鏡（infrared differential interference cont …
NAID 10013601982