WordNet

the membrane that forms the wall of the blastocyst in early development; aids implantation in the uterine wall; "after implantation of the blastocyst in the uterine wall the trophoblast divides into two layers, the chorion and the placenta"

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Gonadotropin-Releasing Hormone Regulates Human Trophoblastic Cell Invasion via TWIST-Induced N-cadherin Expression.

Peng B1, Zhu H, Leung PC.
The Journal of clinical endocrinology and metabolism.J Clin Endocrinol Metab.2015 Jan;100(1):E19-29. doi: 10.1210/jc.2014-1897.
CONTEXT: GnRH and its receptor, GnRHR, were shown to promote trophoblastic cell invasion. Detection of elevated early development-related transcription factor TWIST and adhesion molecule N-cadherin in the invasive trophoblastic cells could suggest that GnRH promotes trophoblastic cell invasion throu
PMID 25313909

Excessive autophagy induces the failure of trophoblast invasion and vasculature: possible relevance to the pathogenesis of preeclampsia.

Gao L1, Qi HB, Kc K, Zhang XM, Zhang H, Baker PN.
Journal of hypertension.J Hypertens.2015 Jan;33(1):106-17. doi: 10.1097/HJH.0000000000000366.
INTRODUCTION: Preeclampsia affects 5-7% of all healthy pregnancies and is characterized by hypertension and proteinuria. Although the pathogenesis of preeclampsia is still not fully understood, a failure of spiral artery transformation and aberrant placental vasculature are considered to be facets o
PMID 25318653

Elastin-derived peptides stimulate trophoblast migration and invasion: a positive feedback loop to enhance spiral artery remodelling.

Desforges M1, Harris LK1, Aplin JD2.
Molecular human reproduction.Mol Hum Reprod.2015 Jan;21(1):95-104. doi: 10.1093/molehr/gau089. Epub 2014 Sep 22.
Elastin breakdown in the walls of uterine spiral arteries during early pregnancy facilitates their transformation into dilated, high-flow, low-resistance channels. Elastin-derived peptides (EDP) can influence cell migration, invasion and protease activity, and so we hypothesized that EDP released du
PMID 25245255

IS-AC-4-6 The differential expression of microRNA between human first trimester villous and extravillous trophoblast cells : PCR array-based approach(Group 4 Perinatology 2,International Session Award Candidate)

Differential Expression of ADAM (a Disintegrin and Metalloproteinase) Genes between Human First Trimester Villous and Extravillous Trophoblast Cells

2) 妊娠高血圧症候群における炎症とアディポサイトカイン : 着床機構と病態発現への関与(シンポジウム2:周産期「妊娠高血圧症候群の基礎と臨床-予防・治療の新戦略に向けて」,第65回日本産科婦人科学会・学術講演会)